CAS: 6136-37-4; 1-Methyl-1H-Purine-2,6(3H,7H)-Dione

上下游产品

8-Chloro-1-Methyl-3,7(9)-Dihydro-Purine-2,6-Dione 6136-36-3
茶碱 Theophylline 58-55-9
咖啡因 3,7-Dihydro-1,3,7-Trimethyl-1H-Purine-2,6-Dione 58-08-2
8-氯-3,7-二氢-1,3,7-三甲基-1H-嘌呤-2,6-二酮 8-Chlorocaffeine 4921-49-7

8-氯-3,7-二氢-1,3,7-三甲基-1H-嘌呤-2,6-二酮置于碘,氯,邻二氯苯体系中,化学反应生成 1-甲基黄嘌呤
参考文献:196. 1:7-二烷基黄嘌呤的合成与性质
标题:196. 1:7-二烷基黄嘌呤的合成与性质
摘要:
DOI:10.1039/jr9450000751

专利信息

专利号:WO-2024154147-A1
优先权日:2023-01-17
标 题 :An efficient process for the synthesis of theacrine
发明人：KANUMURU RAHUL RAJU; KOCHUMALAYIL SHAJI GEORGE; SURANENI RAVIKUMAR; VANA MURALI MOHANARAO
权利人:FERTIS INDIA PVT LTD
摘要:The present invention provides an industrial process for the synthesis of Theacrine with high purity and quality.

专利号:US-7423141-B2
优先权日:1999-03-18
标题:Inhibitors of endothelin-1 synthesis
发明人：CORDER ROGER; SMITH ADRIAN P L; HIGGENBOTTAM TIMOTHY W; ROTHBLATT MARTINE; VANE JOHN; LEES DELPHINE DOMINIQUE MARTHE
权利人:WILLIAM HARVEY RES LTD
摘要:Sequences in human preproendothelin-1 mRNA are described against which antisense oligonucleotides can be used to inhibit the synthesis of endothelin-1. This inhibition of endothelin-1 synthesis may be used to treat diseases where excess production of endothelin-1 is an underlying cause of the symptoms.

专利号:US-5763625-A
优先权日:1995-04-25
标 题:Synthesis and use of β-lapachone analogs
发明人：BOOTHMAN DAVID A; FRYDMAN BENJAMIN J; WITIAK DONALD T
权利人:WISCONSIN ALUMNI RES FOUND
摘要:3-Substituted-β-lapachone analogs and their use either alone or to augment chemotherapy or radiotherapy to induce programmed neoplastic cell death without exhibiting toxicity to surrounding normal cells are disclosed. In particular, 3-allyl-β-lapachones, 3-alkyl-β-lapachones and 3-halo-β-lapachones were found to be Topoisomerase (Topo I) inhibitors. When these analogs are used alone there is a reversible single-strand break in the DNA of neoplastic cells causing apoptosis and cell death in some cells. However, when these analogs are combined with chemotherapy or X-irradiation, an irreversible Topo I-mediated break is achieved. A new and more efficient chemical synthesis of the compounds is also disclosed.

专利号:US-8415493-B2
优先权日:2005-04-22
标 题:Zeolite-like metal organic frameworks (ZMOFS): modular approach to the synthesis of organic-inorganic hybrid porous materials having a zeolite like topology
发明人：EDDAOUDI MOHAMED; LIU YUNLING
权利人:EDDAOUDI MOHAMED; LIU YUNLING; UNIV SOUTH FLORIDA
摘要:The subject invention pertains to metal organic frameworks (MOF) having zeolite-net-like topology, their methods of use, and their modes of synthesis. The ZMOFs are produced by combining predesigned tetrahedral building, generated in situ using heterochelation, with polyfunctional ligands that have the commensurate angle and the required donor groups for the chelation. Each molecular building block is contrasted of a single metal ion and ligands with both heterochelation functionality and bridging functionality. Advantageously, zeolite-net-like MOFs of the subject invention are porous and contain large functional cavities, which is useful for encapsulating large molecules.

专利号:US-5905091-A
优先权日:1996-07-03
标 题 :Enhancement of skin pigmentation by prostaglandins
发明人：FULLER BRYAN B
权利人:UNIV OKLAHOMA
摘要:A composition comprising a carrier and prostaglandin effective in stimulating synthesis of melanin in a human melanocyte thereby enhancing pigmentation of the human skin and optionally comprising a lysosomotropic agent, a phosphodiesterase inhibitor, and/or methylxanthines, and a method of use of the composition. Use of this composition promotes tanning of the human skin and increases photoprotection from ultraviolet radiation.

专利号:US-2024317750-A1
优先权日:2021-06-24
标 题 :An Efficient Process for the Synthesis of Methylliberine and Polymorphs Thereof
发明人：KANUMURU RAHUL RAJU; SHAJI GEORGE KOCHUMALAYIL; VANA MURALI MOHANARAO; SURANENI RAVIKUMAR; ANINDYA SIL
权利人:FERTIS INDIA PVT LTD
摘要:The present invention discloses a synthetic procedure for the preparation of Methylliberine and its polymorphs thereof in a simple and efficient manner.