专利号:CN-107325130-A 优先权日:2016-12-30 标 题 :Synthesis of Novel Perylimide Cyclometallic Iridium Complexes and Its Application of Fluorescence-Phosphorescence Dual Emission Controlled by Solution Concentration
专利号:CN-107325130-B 优先权日:2016-12-30 标 题:Synthesis of Novel Peryleneimide Cyclometallic Iridium Complexes and Their Application in Controlling Fluorescence-Phosphorescence Dual Emission by Solution Concentration
专利号:US-4588732-A 优先权日:1982-12-21 标题:Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors 发明人:BROWNE LESLIE J 权利人:CIBA GEIGY CORP 摘要:Disclosed are compounds of the formula I (I) or a 5,6,7,8-tetrahydro derivative thereof, wherein R1 is hydrogen, halogen, lower alkyl, lower alkoxy, hydroxy, or aryl-lower alkoxy in which aryl represents phenyl or phenyl substituted by lower alkoxy, lower alkyl, halogen or trifluoromethyl; R2 represents hydrogen, halogen, or lower alkyl; C represents carboxy, lower alkoxycarbonyl, unsubstituted or mono- or di-(lower alkyl) substituted carbamoyl, cyano, formyl, hydroxymethyl, 5-tetrazolyl, dihydro-2-oxazolyl, dihydro-2-oxazolyl substituted by lower alkyl, or hydroxycarbamoyl; and (a) A represents ethenylene or ethenylene substituted by lower alkyl; B is straight chain or branched alkylene of 1 to 12 carbon atoms, alkynylene or alkenylene of 2 to 12 carbon atoms, phenylene-lower alkylene, phenylene-lower alkenylene, phenylene, or phenylene-(thio or oxy)-lower alkylene; or (b) A represents a direct bond; B represents lower alkylenephenylene, phenylene lower alkylene, phenylene, lower alkylene-(thio or oxy)-lower alkylene, lower alkylene-(thio or oxy)-phenylene, phenylene-(thio or oxy)-lower alkylene, phenylene-lower alkenylene, lower alkylenephenylene-lower alkenylene, or straight chain or branched alkadienylene of 5 to 12 carbon atoms; or a pharmaceutically acceptable salt thereof; and methods of synthesis thereof. Said compounds are useful as selective thromboxane synthetase inhibitors for the treatment of diseases such as cerebral ischaemia, shock, thrombosis and ischaemic heart disease.