CAS: 33509-43-2; 4-Amino-6-(Tert-Butyl)-3-Mercapto-1,2,4-Triazin-5(4H)-One

上下游产品

嗪草酮 4-Amino-6-Tert-Butyl-3-Methylthio-1,2,4-Triazin-5(4H)-One 21087-64-9

1,1-二氯频哪酮置于盐酸,双氧水,1-Butyl-3-Methylimidazolium Tetrafluoroborate体系中,用 水 作为反应溶剂,化学反应 14.0H,反应生成 4-氨基-6-叔丁基-3-巯基-1,2,4-三嗪-5(4H)-酮
参考文献:一种嗪草酮中间体的新型合成方法
标题:一种嗪草酮中间体的新型合成方法
摘要:本发明公开了一种嗪草酮中间体的新型合成方法.以频那酮(甲基叔丁基酮)为初始原料,经氯化,水解,氧化,缩合等反应步骤生产嗪草酮的中间体三嗪酮.优点为:(1)反应条件温和,总收率达92.4%;(2)采用双氧水代替次氯酸钠做为氧化剂,在室温条件下进行氧化反应,操作方便,副产物是水,减少了生产过程的含盐废水等污染物的排放;(3)反应结束后层析分离中间体和催化剂,含有催化剂的水相循环使用.

专利信息

专利号:US-4326056-A
优先权日:1980-05-29
标 题 :Process for the production of 4-amino-6-tert. butyl-3-mercapto-1,2,4-triazin-5-one
发明人：KLEEMANN AXEL; LEHAMNN BERND; KLENK HERBERT
权利人:DEGUSSA
摘要:4-amino-6-tert.butyl-3-mercapto-1,2,4-triazin-5-one of the formula is produced by reacting pivaloyl cyanide and isobutylene in the presence of acetic acid and sulfuric acid, hydrolyzing the reaction mixture in the presence of water and reacting the trimethyl pyruvic acid formed with thiocarbohydrazide. The triazinone is an important intermediate product in the synthesis of the known herbicide 4-amino-6-tert.butyl-3-methylmercapto-1,2,4-triazin-5-one.

专利号:US-4370498-A
优先权日:1980-03-08
标题 :Preparation of α-ketocarboxylic acid N-acylamides
发明人：BONSE GERHARD; BLANK HEINZ U
权利人:BAYER AG
摘要:α-Ketocarboxylic acid N-acylamides of the formula n n R.sup.1 --CO--CO--NH--CO--R.sup.2 n n in which n R 1 is an optionally substituted aliphatic radical with up to 12 carbon atoms, an optionally substituted cycloalkyl radical with 3 to 10 carbon atoms, an optionally substituted heterocyclic radical, and n R 2 is an optionally substituted aliphatic radical with up to 8 carbon atoms or an optionally substituted phenyl radical, n are prepared by reacting an acyl cyanide of the formula n n R.sup.1 --CO--CN n n with a carboxylic acid anhydride of the formula n n R.sup.2 --CO--O--CO--R.sup.2 n n in the presence of a strong acid, and then adding water to the reaction mixture. The products can be used directly in the synthesis of known herbicides.

专利号:US-4345100-A
优先权日:1980-01-22
标题 :Preparation of α-ketocarboxylic acid N-tert.-butylamides
发明人：BONSE GERHARD; BLANK HEINZ U
权利人:BAYER AG
摘要:A process for the preparation of an α-ketocarboxylic acid N-tert.-butylamide of the formula n n R--CO--CO--NH--C(CH.sub.3).sub.3 n n in which n R is an aliphatic radical with up to 8 carbon atoms, a cycloalkyl radical with 3 to 6 carbon atoms, a phenyl or naphthyl radical or a heterocyclic radical, n comprising reacting an acyl cyanide of the formula n n R--CO--CN n n with tert.-butyl methyl ether of the formula n n (CH.sub.3).sub.3 C--O--CH.sub.3 n n at a temperature between about 0° and 80° C. in the presence of an acid which is capable of activating the ether of formula (III) under the reaction conditions to give a tert.-butyl carbonium ion, and then hydrolyzing the reaction mixture. Advantageously the acyl cyanide is pivaloyl cyanide or benzoyl cyanide and is reacted with an approximately equimolar amount of the ether in the presence of about 1.1 to 1.5 times the molar amount of concentrated sulphuric acid as the activating acid. The products are useful as intermediates in the synthesis of known herbicides.

专利号:US-4057583-A
优先权日:1974-12-27
标题 :Process for the preparation of pinacolone
发明人：MERZ WALTER; NACHTSHEIM DIETER
权利人:BAYER AG
摘要:The invention provides a novel synthesis for pinacolone comprising reacting 2-methyl-but-2-ene and/or 2-methyl-but-1-ene with an aqueous inorganic acid, adding formaldehyde gradually at a temperature between 50° and 200° C at a rate of 0.5 - 1.5 moles of formaldehyde per mole of butene compound, allowing the mixture to react further, and separating the pinacolone by distillation.

专利号:DE-3115970-A1
优先权日:1981-04-22
标 题 :'5-ACYLOXY-4 (5H) -OXAZOLONIUM SALTS, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF AS INTERMEDIATE PRODUCTS FOR THE SYNTHESIS OF HERBICIDALLY ACTIVE TRIAZINONES'

专利号:EP-0063349-B1
优先权日:1981-04-22
标 题:5-acyloxy-4(5h)-oxazolonium salts, process for their preparation and their use as intermediates in the synthesis of herbicidal triazinones