专利号:US-8647848-B2 优先权日:2008-06-13 标题:Enzymatic synthesis of sphingolipids 发明人:HOLLMANN FRANK; THUM OLIVER; TOELLE CHRISTOPH; PROVINZANO ANGELO; KOREVAAR CORNELIS GERRIT NIJS 权利人:HOLLMANN FRANK; THUM OLIVER; TOELLE CHRISTOPH; PROVINZANO ANGELO; KOREVAAR CORNELIS GERRIT NIJS; EVONIK GOLDSCHMIDT GMBH 摘要:The invention relates to the enzymatic synthesis of sphingolipids and compositions that contain sphingolipids from lysosphingolipids and carbonic esters, and to cosmetic, dermatological or pharmaceutical formulations containing said sphingolipids or compositions.
专利号:US-9586984-B2 优先权日:2007-04-09 标题:One-pot synthesis of alpha/beta-O-glycolipids 发明人:GERVAY-HAGUE JACQUELYN; DU WENJUN; KULKARNI SUVARN S; SCHOMBS MATTHEW 权利人:UNIV CALIFORNIA 摘要:The present invention provides a one-pot method of preparing an unprotected α-O-glycolipid. The first step involves contacting a protected α-iodo sugar with a catalyst and a lipid comprising a hydroxy group, under conditions sufficient to prepare a protected α-O-glycolipid. The second step involves deprotecting the protected α-O-glycolipid under conditions sufficient to prepare the unprotected α-O-glycolipid, wherein the contacting and deprotecting steps are performed in a single vessel. The present invention also provides a one-pot method of preparing an unprotected β-O-glycolipid following the steps for the preparation of the unprotected α-O-glycolipid.
专利号:JP-H07508889-A 优先权日:1993-05-06 标题 :Enzymatic synthesis of ceramides and hybrid ceramides
专利号:EP-0651817-B1 优先权日:1993-05-06 标题 :Enzymatic synthesis of ceramides and hybrid ceramides
专利号:JP-2011522550-A 优先权日:2008-06-13 标题:Enzymatic synthesis of sphingolipids
专利号:WO-9426919-A1 优先权日:1993-05-06 标题 :Enzymatic synthesis of ceramides and hybrid ceramides