CAS: 35386-24-4; 1-(2-Methoxyphenyl)Piperazine

上下游产品

CAS号110-85-0 哌嗪 | CAS号578-57-4 邻溴苯甲醚 | CAS号821-48-7 二(2-氯乙基)胺盐酸盐 | CAS号90-04-0 邻氨基苯甲醚 | CAS号766-51-8 邻氯苯甲醚 | CAS号7542-23-6 piperazinium ch... | CAS号5464-78-8 1-(2-甲氧基苯基)哌嗪盐酸盐 | CAS号115755-26-5 1-(2-methoxyphe... | CAS号6163-58-2 三(2-甲苯基)膦 | CAS号144649-74-1 1-(2-methoxyphe... | CAS号146714-63-8 4-(2-Methoxyphe... | CAS号219125-59-4 2-[4-(2-甲氧基苯基)哌... | CAS号21091-60-1 2-(4-苄基-1-哌嗪)甲氧基苯 | CAS号21103-33-3 4-4 -(2-甲氧基-苯基)-... | CAS号21057-39-6 2-chloro-1-[4-(... | CAS号58260-69-8 2-piperazin-1-y... | CAS号57149-07-2 萘哌地尔 | CAS号127931-16-2 S-(-)-Naftopidil | CAS号127931-15-1 R-(+)-Naftopidil

N1-(2-Methoxyphenyl)Ethane-1,2-Diamine置于碳酸氢钠,N,N'-二环己基碳二亚胺,Sodium Iodide,Diborane(6)体系中,用 四氢呋喃,二氯甲烷,丙酮 用作溶剂,化学反应 55.5H,反应生成1-(2-甲氧苯基)哌嗪
参考文献:Cossec,B.; Marsura,A.; Luu-Duc,C.,Pharmazie,1989,Vol. 44,# 9,P. 643
标题:Cossec,B.; Marsura,A.; Luu-Duc,C.,Pharmazie,1989,Vol. 44,# 9,P. 643

专利信息

专利号:US-11912647-B2
优先权日:2020-05-22
标 题:Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation
发明人：CRICH DAVID; HETTIKANKANAMALAGE ASIRI; HILL JARVIS
权利人:UNIV GEORGIA
摘要:In one aspect, the disclosure relates to a method for the direct synthesis of complex N,N,O-trisubstituted hydroxylamines by N—O bond formation. In another aspect, the method can successfully be employed using a wide variety of commercially available alcohols and secondary amines and enables the construction of large fragment-based libraries of trisubstituted hydroxylamines for drug discovery purposes. Also disclosed are N,N,O-trisubstituted hydroxylamines having low basicity, high stability at ambient temperatures, and an inherent lack of reactivity towards acetylating and sulfonylating enzymes that confer mutagenicity on less-substituted hydroxylamines.

专利号:US-2005019747-A1
优先权日:2002-08-07
标 题 :Nanoliter-scale synthesis of arrayed biomaterials and screening thereof
发明人：ANDERSON DANIEL G; LEVENBERG SHULAMIT; LANGER ROBERT S
摘要:A method of screening cell-polymer interactions. The method includes depositing monomers as a plurality of discrete elements on a substrate, causing the deposited monomers to polymerize, thereby creating an array of discrete polymer elements on the substrate, incubating the substrate in a cell-containing culture medium, and characterizing a predetermined cell behavior on each polymer element.

专利号:WO-2005021522-A1
优先权日:2003-08-28
标 题:Synthesis of 1-‘4-(2-methoxyphenyl) piperazin-1-yl !-3-(2,6-dioxopiperidin-1-yl) propane
发明人：SALMAN MOHAMMAD; SHARMA SOMESH; YADAV GYAN CHAND
权利人:RANBAXY LAB LTD; SALMAN MOHAMMAD; SHARMA SOMESH; YADAV GYAN CHAND
摘要:The present invention relates to processes for the syntheses of 1-[4-(2-methoxyphenyl)piperazin-1-yl]-(2,6-dioxopiperidin-1-yl)propane and its pharmaceutically acceptable salts, preferably hydrochloride having uro-selective α1-adrenoceptor antagonistic activity. The compound holds promise for treating benign prostatic hyperplasia (BPH).

专利号:WO-2005021521-A1
优先权日:2003-08-28
标题:Preparation of 1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-3-(2,6-dioxopiperidin-1-yl) propane hydrochloride
发明人：ANAND NITYA; SINHA NEELIMA; JAIN SANJAY; MEHTA ANITA
权利人:RANBAXY LAB LTD; ANAND NITYA; SINHA NEELIMA; JAIN SANJAY; MEHTA ANITA
摘要:The present invention relates to processes for the synthesis of 1-[4-(2­methoxyphenyl)piperazin-1-yl]-3-(2,6-dioxopiperidin-1-yl) propane hydrochloride having protracted uro-selective (α1-adrenoceptor antagonistic activity. The compound holds promise for treating benign prostatic hyperplasia (BPH).

专利号:WO-9919297-A9
优先权日:1997-10-15
标题 :Synthesis of azetidine derivatives
发明人：CHEN ZHENGMING; KOLB HARTMUTH C; RICHARDSON PAUL; HUANG ZHI-MIN
权利人:COELACANTH CHEMICAL CORP; CHEN ZHENGMING; KOLB HARTMUTH C; RICHARDSON PAUL; HUANG ZHI MIN
摘要:The present invention provides compound having formula (I) useful as building blocks for combinatorial libraries and methods of making such compounds. Also provided are compositions comprising the compounds.

专利号:US-6313297-B1
优先权日:1998-01-17
标题:Base-catalyzed synthesis of 1-aryl-4-(aryl ethyl)piperazines from aromatic olefins and 1-arylpiperazines
发明人：HERWIG JUERGEN; BELLER MATTHIAS; BREINDL CLAUDIA
权利人:AVENTIS RES & TECHNOLOGIES; GMBH & CO KG
摘要:A process for preparing a 1-aryl-4-(arylethyl)piperazine of the formula (I)by reacting a 1-arylpiperazine of the formula (II)with an aromatic olefin of the formula (III)in an inert solvent in the presence of at least one basic catalyst, where in the formulae (I) to (III)Ar and Ar' independently of one another are an aryl radical, selected from the group of the fused and unfused C6-C22-aromatics and the fused or unfused C5-C22-heteroaromatics which have at least one nitrogen, oxygen or sulfur atom in the ring; andR1 and R2 independently of one another are a hydrogen atom, a C1-C8-alkyl radical or an aryl radical Ar.