CAS: 56309-94-5; Bicyclohexane-4,4-Dione Monoethylene Ketal

相似化合物

4746-97-8 51716-62-2 93245-98-8

4,4'-二氧代联环己烷,乙二醇置于硫酸体系中,用 氯仿 作为反应溶剂,化学反应 10.5H,反应生成 双环己酮乙二醇单缩酮
参考文献:塩,酸発生剤,レジスト組成物及びレジストパターンの製造方法
标题:塩,酸発生剤,レジスト組成物及びレジストパターンの製造方法
摘要:本发明旨在提供一种含有盐和该盐的光阻组合物,可用于制造具有非常好掩模误差因子(mef)的光刻图案.解决方案是提供式(i)所表示的盐,酸发生剂和包含它们的光阻组合物.其中,Q1和q2分别表示氟原子或全氟烷基等,R1和r2分别表示氢原子,氟原子或全氟烷基等,Z表示0-6的整数,X1表示*-Co-O-,*-O-Co-,*-O-Co-O-或*-O-,L1表示单键或饱和碳氢基,A1表示带有取代基的二价脂环式碳氢基,Ra表示带有取代基的脂环式碳氢基,其中包含的-Ch2-可以替换为-O-,-S-,-So2-或-Co-.但是,该脂环式碳氢基中至少有一个-Ch2-被替换为-O-或-Co-.z +表示有机阳离子.[选择图]无.

专利信息

专利号:US-8222458-B2
优先权日:2008-06-13
标题 :Process or synthesis of (3S)- and (3R)-3-hydroxy-beta-ionone, and their transformation to zeaxanthin and beta-cryptoxanthin
发明人：KHACHIK FREDERICK; CHANG AN-NI
权利人:KHACHIK FREDERICK; CHANG AN-NI; UNIV MARYLAND
摘要:Disclosed is a process for the synthesis of (3R)-3-hydroxy-β-ionone and its (3S)-enantiomer in high optical purity from commercially available (rac)-α-ionone. The key intermediate for the synthesis of these hydroxyionones is 3-keto-α-ionone ketal that was prepared from (rac)-α-ionone after protection of this ketone as a 1,3-dioxolane. Reduction of 3-keto-α-ionone ketal followed by deprotection, lead to 3-hydroxy-α-ionone that was transformed into (rac)-3-hydrox-β-ionone by base-catalyzed double bond isomerization in 46% overall yield from (rac)-α-ionone. The racemic mixture of these hydroxyionones was then resolved by enzyme-mediated acylation in 96% ee. (3R)-3-Hydroxy-β-ionone and its (3S)-enantiomer were respectively transformed to (3R)-3-hydroxy-(β-ionylideneethyl)triphenylphosphonium chloride [(3R)-C 15 -Wittig salt] and its (3S)-enantiomer [(3S)-C 15 -Wittig salt] according to known procedures. Double Wittig condensation of these Wittig salts with commercial available 2,5- dimethtylocta-2,4,6-triene-1,8-dial provided all 3 stereoisomers of zeaxanthin. Similarly, (3R)-C 15 -Wittig and its (3S)-enantiomer were each coupled with β-apo-12′-carotenal.

专利号:US-4322353-A
优先权日:1980-04-18
标题:Synthesis of dioxabicyclo(3.2.1)octanes and oxepanes
发明人：HAJOS ZOLTAN G; WACHTER MICHAEL P
权利人:ORTHO PHARMA CORP
摘要:The synthesis of C-4 alkyl homologs of racemic (1RS, 4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid and the corresponding (1RS,4RS,5RS) - derivative is described. The dioxabicylo[3.2.1]octanes are useful as contragestational agents.

专利号:US-5597931-A
优先权日:1992-03-30
标 题:Total synthesis of taxol and analogues thereof
发明人：DANISHEFSKY SAMUEL J; MASTERS JOHN; YOUNG WENDY; LINK J THOMAS; ISAACS RICHARD; SNYDER LAWRENCE B
权利人:SLOAN KETTERING INST CANCER
摘要:The present invention provides three basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogues of taxol and nortaxol.

专利号:US-4482730-A
优先权日:1981-09-24
标题:Synthesis of dioxabicyclo[3.2.1]octanes and oxepanes
发明人：HAJOS ZOLTAN G; WACHTER MICHAEL P
权利人:ORTHO PHARMA CORP
摘要:The synthesis of C-4 alkyl homologs of racemic (1RS,4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid and the corresponding (1RS,4RS,5RS) - derivative is described. The dioxabicylo[3.2.1]octanes are useful as contragestational agents.

专利号:US-5488116-A
优先权日:1992-03-30
标 题:Total synthesis of taxol and analogues thereof
发明人：DANISHEFSKY SAMUEL J; BORNMANN WILLIAM G; QUENEAU YVES; MAGEE THOMAS V; KROL WALTER J; MASTERS JOHN J; JUNG DAVID K
权利人:SLOAN KETTERING INST CANCER
摘要:The present invention provides three basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogues of taxol and nortaxol.

专利号:US-5527924-A
优先权日:1992-03-30
标题 :Total synthesis of taxol
发明人：DANISHEFSKY SAMUEL J; BORNMANN WILLIAM G; QUENEAU YVES; MAGEE THOMAS V; KROL WALTER J
权利人:SLOAN KETTERING INST CANCER
摘要:The present invention provides two basic routes for the total synthesis of taxol having the structure: The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogs to taxol. Both the intermediates and analogs to taxol may prove to be valuable anticancer agents.