CAS: 619-84-1; 4-Dimethylaminobenzoic Acid

上下游产品

CAS号124-38-9 二氧化碳 | CAS号95752-87-7 4-(5,5-dimethyl... | CAS号586-77-6 4-溴-N,N-二甲基苯胺 | CAS号1703-46-4 4-(二甲氨基)苄醇 | CAS号100-10-7 对二甲氨基苯甲醛 | CAS号10287-53-3 对-N,N-二甲氨基苯甲酸乙酯 | CAS号66379-84-8 2,2,2-trichloro... | CAS号150-13-0 对氨基苯甲酸 | CAS号616-38-6 碳酸二甲酯 | CAS号50-00-0 甲醛 | CAS号4755-50-4 4-二甲氨基苯甲酰氯 | CAS号41263-74-5 4-甲氨基-3-硝基苯甲酸 | CAS号1874-35-7 N,N-dimethyl-4-... | CAS号99-98-9 对氨基-N,N-二甲基苯胺 | CAS号134868-23-8 4-dimethylamino... | CAS号109-52-4 正戊酸 | CAS号98-89-5 环己甲酸 | CAS号2562-71-2 2-[4-(二甲基氨基)苯基]苯并咪唑 | CAS号71254-71-2 4-甲氨基-3-硝基苯甲酸乙酯 | CAS号530-44-9 4-(二甲氨基)二苯甲酮

2,2,2-三氯-1-(4-(二甲氨基)苯基)乙醇置于sodium Hydroxide,双氧水体系中,用 甲醇 作为反应溶剂,化学反应 10.0H,以98%的收率获得产物4-二甲氨基苯甲酸
参考文献:Menegheli,Paulo; Rezende,Marcos Caroli; Zucco,Cezar,Synthetic Communications,1987,Vol. 17,# 4,P. 457-464
标题:Menegheli,Paulo; Rezende,Marcos Caroli; Zucco,Cezar,Synthetic Communications,1987,Vol. 17,# 4,P. 457-464

专利信息

专利号:US-7598291-B2
优先权日:2004-09-02
标题 :Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin
发明人：NIMNI MARCEL; HAN BO
权利人:NIMNI MARCEL; HAN BO
摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid, a lipoic acid analogue or derivative, a bioflavonoid, a constituent of ginkgo, or an isoflavone. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

专利号:US-2010160244-A1
优先权日:2004-09-02
标 题 :Methods and compositions for enhancing collagen, proteoglycan, and glutathione synthesis in the skin
发明人：NIMNI MARCEL; HAN BO
权利人:NIMNI MARCEL; HAN BO
摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids or hydrolyzed whey protein; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid or a lipoic acid analogue or derivative. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-9757317-B2
优先权日:2014-09-12
标题 :Cosmetic compositions and methods for inhibiting melanin synthesis
发明人：LAUGHLIN II LEO TIMOTHY; HAKOZAKI TOMOHIRO; GUPTA SHIKHAR
权利人:PROCTER & GAMBLE
摘要:A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include bisabolol, undecylenoyl phenylalanine and/or hexyldecanol, and a material selected from the group consisting of ethyl palmitate, stearyl alcohol, bis (2-ethylhexyl) adipate, bis (2-ethylhexyl) maleate, 5-pentadecanol, 1-stearoyl-rac-glycerol, bis (2-ethylhexyl) sebacate, and mixtures thereof. A method of reducing the synthesis of melanin by using the cosmetic compositions is also disclosed herein.

专利号:US-9498420-B2
优先权日:2013-05-01
标 题:Cosmetic compositions and methods for inhibiting melanin synthesis
发明人：LAUGHLIN II LEO TIMOTHY; HAKOZAKI TOMOHIRO; TANAKA SHUHEI
权利人:PROCTER & GAMBLE
摘要:A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include batyl alcohol, undecylenoyl phenylalanine, hexyldecanol, and bisabolol. A method of reducing the synthesis of melanin by using the cosmetic compositions is also disclosed herein.

专利号:US-9982072-B2
优先权日:2013-10-30
标 题 :Synthesis of acetal compounds
发明人：LOCCUFIER JOHAN
权利人:AGFA GRAPHICS NV; AGFA NV
摘要:A process for the preparation of optionally asymmetric acetal compounds includes reacting a compound containing a hydroxyl group with a vinylether compound in the presence of a zwitterionic catalyst including at least one basic nitrogen containing structural fragment and at least one sulfonic acid group in its structure, with the proviso that a molar ratio of the basic nitrogen to sulfonic acid is 1:1.