CAS: 96-18-4; 1,2,3-Trichloropropane

上下游产品

2-iodo-propane methylene chloride propene allyl iodid 2-Methylhexane triptane 2,2-dimethylpentane tritetradecanoylglycerol

3-氯丙烯置于盐酸 氯体系中,用 甲醇 作为反应溶剂,化学反应生成 1,2,3-三氯丙烷
参考文献:烯烃氯化的极性反应常数.氯离子和溴离子的过渡态相似和不同.
标题:烯烃氯化的极性反应常数.氯离子和溴离子的过渡态相似和不同.
摘要:在25oc下通过直接动力学方法在甲醇中获得的用于将游离氯加成到烯烃中的极性反应常数ϱ * Cl 2为-2.9,而ϱ * Br 2为-3.1.从溴化到氯化的变化与大的反应性增加但选择性的小下降有关.根据harmond假设以及在卤化过渡态中电荷分布对桥连原子的依赖性来讨论此结果.
DOI:10.1016/s0040-4039(00)87590-5

专利信息

专利号:US-2023111600-A1
优先权日:2019-12-17
标题 :Polymeric fatty acid compounds for the treatment of fibrous amino acid-based substrates, especially hair
发明人：WAGNER ROLAND; STREICHER KATHARINA; ROHMANN LAURA; WENSKE CHRISTIAN; HAVELI SHRUTISAGAR DATTATRAYA
权利人:MOMENTIVE PERFORMANCE MAT GMBH
摘要:The present invention is directed at mono-, di- or polyquaternary ammonium compounds of the formula (I) wherein x is 1 to 50, and F can be the same or different and is represented by the general formula (II) wherein at least one of the optionally substituted and optionally functional-group-containing hydrocarbon radicals R 1 , R 2 , R 3 , R 4 or R 5 contains at least one estolide moiety comprising two or more ester or amide moieties. The invention also relates to a process for the synthesis of such compounds, the use of the compounds in cosmetic formulations for skin and hair care, cosmetic compositions for the treatment of fibers, and compositions containing one or more of the compounds for the treatment of hair.

专利号:WO-2009049476-A1
优先权日:2007-09-20
标题 :Process for the manufacture of (+)-biotin
发明人：CHEN FEN-ER; DAI HUI-FANG; HUANG JIAN; XIONG FEI; JING SHU-PING
权利人:DSM IP ASSETS BV; UNIV FUDAN; CHEN FEN-ER; DAI HUI-FANG; HUANG JIAN; XIONG FEI; JING SHU-PING
摘要:Disclosed are processes for preparing synthetic biotin intermediates and a process for preparing biotin using said intermediates. In particular, disclosed is a process for the stereoselective total synthesis of the natural product (+)-biotin of formula (I).

专利号:US-6472531-B1
优先权日:1994-09-19
标题 :Synthesis of 3-[4-(2-aminoethoxy)-benzoyl]-2-aryl-6-hydroxybenzo[b]thiophenes
发明人：LABELL ELIZABETH SMITH; MCGILL JOHN MCNEILL; MILLER RANDAL SCOT
权利人:LILLY CO ELI
摘要:The present invention is directed to chemical processes for preparing 2-aryl-6-hydroxy-3-[4-(2-aminoethoxy)benzoyl]benzo[b]-thiophenes. The present invention is also directed to crystalline solvates and a non-solvated crystalline form of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]-benzo[b]thiophene hydrochloride, as well as processes for their preparation.

专利号:US-5637775-A
优先权日:1994-04-28
标 题 :Process for the preparation of halogenated ethers
发明人：GALLEGRA PASQUALE; DEGISCHER GERHARD
权利人:SCHWEIZERHALL SAEUREFAB
摘要:The invention relates to a process for the preparation of compounds of formula I (I) wherein R is mono- or disubstituted lower alkyl, the substituents being selected from halogen and lower alkoxy, with the proviso that said substituents are not present at the carbon atom of the lower alkyl radical R linking the group R to the remainder of the molecule of formula I; R1 is hydrogen, lower alkyl, phenyl or phenyl-lower alkyl; and X is chloro or bromo; which comprises reacting an acetal of formula II, (II) wherein R and R1 are as defined above, with at least one compound of formula R2-X, wherein R2 is hydrogen or X-SO, in which last mentioned case the reaction mixture must contain a catalytically effective amount of N,N-di-lower alkyl-lower alkanoylamide(s) and wherein X is as defined with respect to the compounds of formula I. The compounds of formula I are useful intermediates, suitably for the synthesis of pharmaceutical or fungicidal compounds.

专利号:US-4111933-A
优先权日:1976-04-30
标题:Protection of functional groups during reaction and their subsequent restoration
发明人：ECKERT HEINER; UGI IVAR; KABBE HANS-JOACHIM
权利人:BAYER AG
摘要:In the process for preparing an organic compound of the formula n n A' -- X n n in which n X is an amino group, a hydroxyl group or a carboxyl group, and n A' is the remainder of the molecule, from an organic compound of the formula n n A -- X n n in which n A is the remainder of the molecule which can undergo reaction to form A', by converting A -- X into a compound of the formula n n A -- Z -- COOR n n in which n Z is --NH--, --O-- or a direct C--C bond, and n R is a radical of the formula ##STR1## IN WHICH Y is a direct C--C single bond, the --CHâ•?CH-- group or an arylene group, n R 1 to R 4 each independently is hydrogen, halogen or an alkyl, aryl, aralkyl, alkoxycarbonyl, alkylaminocarbonyl, arylaminocarbonyl or cycloalkylaminocarbonyl radical, or n R 1 + r 2 and R 3 + R 4 each independently completes a 5- or 6-membered carbocyclic ring, or n R 1 and R 3 conjointly with the grouping --C--Y--C-- forms a carbocyclic ring with 5 or 6 carbon atoms, and Hal is halogen, n Thereby to protect X, then converting A -- Z -- COOR into a compound of the formula n n A' -- Z -- COOR n n and then treating the compound A' -- Z -- COOR to restore the group X, the improvement which comprises effecting the treatment of the compound A' -- Z -- COOR with an alkali metal compound of a complex of monovalent cobalt. The process is applicable particularly to aminocarboxylic acids including intermediates from various stages of the synthesis of penicillins and cephalosporis.

专利号:US-3970727-A
优先权日:1973-07-30
标题:Halogenated esters of phosphorus-containing acids
发明人：D ALELIO GAETANO F
权利人:ALELIO GAETANO F D
摘要:This invention deals with new phosphorus-containing esters having the formula ##EQU1## WHEREIN N IS AN INTEGER HAVING A VALUE OF AT LEAST 2; Z represents an organic moiety having a valency of n and having a plurality of polymeric repeating units therein at least two of which have valencies attached to said --CH 2 P(O)(ORCX=CXR') 2 groups of the above formula; n R represents a divalent hydrocarbon radical containing 1-20 carbon atoms; n R' represents X, hydrogen or R'; n R' represents a monovalent hydrocarbon radical containing 1-20 carbon atoms; and n X represents chlorine or bromine. These new esters are useful particularly as fire retardants, agricultural chemicals, fuel additives, plasticizers, monomers and intermediates for the synthesis of other useful derivatives.