CAS: 1009-35-4; 4-Fluoro-3-Nitrobenzonitrile

相似化合物

42564-51-2 453-71-4 859855-53-1

上下游产品

4-chloro-3-nitrobenzonitrile 4-fluorobenzonitrile 4-fluoro-3-nitrobenzaldehyde Diphenylmethyl-2-nitro-4-cyano-phenolat 4-(methylamino)-3-nitrobenzonitrile 4-(isopropylamino)-3-nitrobenzonitrile 3-amino-4-fluorobenzonitrile

对氟苯腈置于nitronium Tetrafluoborate体系中,用 环丁砜 用作溶剂,化学反应生成4-氟-3-硝基苯甲腈
参考文献:芳烃替代品.Vii.1Friedel-Crafts 型芳烃硝化2
标题:芳烃替代品.Vii.1Friedel-Crafts 型芳烃硝化2
摘要:在均相四亚甲基砜溶液中研究了芳烃与硝基卤化物,四氧化二氮,五氧化二氮和稳定的硝鎓盐的 Friedel-Crafts 型硝化.发现了一种由硝酸hf和bf2制备四氟硼酸硝鎓的简单新方法.氟硼酸盐硝化制备硝基硝基脲的范围扩大到各种取代芳烃.
Doi:10.1021/ja01483A016

专利信息

专利号:US-9303041-B2
优先权日:2012-08-21
标题 :Haptens of olanzapine
发明人：DONAHUE MATTHEW GARRETT; GONG YONG; SALTER RHYS; HRYHORENKO ERIC; DECORY THOMAS R; REMMERIE BART; SANKARAN BANUMATHI
权利人:JANSSEN PHARMACEUTICA NV; ORTHO CLINICAL DIAGNOSTICS INC
摘要:The invention relates to compounds of Formula I, wherein R 1 , R 2 , and R 3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from olanzapine. The invention also relates to conjugates of an olanzapine hapten and a protein.

专利号:US-12202782-B2
优先权日:2020-11-19
标 题:Processes and intermediates for preparing MCL1 inhibitors
发明人：DIXON DARRYL D; ISCHAY MICHAEL A; JOHNSON TREVOR C; MERIT JEFFREY E; REGENS CHRISTOPHER S; STANDLEY ERIC A; STEINHUEBEL DIETRICH P
权利人:GILEAD SCIENCES INC
摘要:The present disclosure relates to methods and intermediates for the synthesis of certain compounds that inhibit MCL1, for use in the treatment of cancers.

专利号:WO-2019038779-A1
优先权日:2017-08-21
标 题:NEW PROCESS FOR PREPARING ALECTINIB INTERMEDIATE
发明人：APPAYE KALIYAPERUMAL SRINIVASAN; TALASANI SHYAM SUNDER REDDY; SAMATHAM NAGALINGAM; KONDURI SRINIVASA KRISHNA MURTHY; BUDIDETI SHANKAR REDDY; MUDDASANI PULLA REDDY; NANNAPANENI VENKAIAH CHOWDARY
权利人:NATCO PHARMA LTD
摘要:The present invention relates to a new process for the preparation of 2- (4-ethyl-3-iodophenyl) -2-methylpropanoic acid of formula (I), (I) which is a key intermediate in the synthesis of Alectinib or its salt of formula (II).

专利号:CN-108997177-A
优先权日:2018-09-04
标题 :A kind of microwave-promoted method for the synthesis of N-benzenesulfonylnitroaniline compounds