CAS: 118-45-6; 5-Chloroisobenzofuran-1,3-Dione

相似化合物

942-06-3 117-21-5 4466-59-5

上下游产品

4-氯邻苯二酸 4-Chlorophthalic Acid 89-20-3
苯酐 Phthalic Anhydride 85-44-9
3-氯邻苯二甲酸 3-Chlorobenzene-1,2-Dicarboxylic Acid 27563-65-1
氯化偏苯三酸酐 Trimellitic Anhydride Acid Chloride 1204-28-0

4-氯邻苯二酸 100.0 °C,5.33 Kpa 条件下,反应生成4-氯代苯酐
参考文献:一种4-卤代苯酐的制备方法及利用该方法得到的4-卤代苯酐
标题:一种4-卤代苯酐的制备方法及利用该方法得到的4-卤代苯酐
摘要:本发明公开了一种4‑卤代苯酐的制备方法及利用该方法得到的4‑卤代苯酐,所述制备方法包括:(1)将2‑卤代丁二烯和融化的顺酐引入微通道反应器内,经反应得到中间产物i;(2)在过渡金属盐催化剂,碱性物质和含氧气体存在下,所述中间产物i在溶剂中进行反应得到中间产物ii,对所述中间产物ii进行后处理得到中间产物iii;(3)对所述中间产物iii进行熔融脱水,得到所述4‑卤代苯酐.本发明提供的以2‑卤代丁二烯和顺酐为原料,采用连续环加成‑氧化芳构化制备4‑卤代苯酐的方法,该方法反应效率高,所得产品无需异构体分离.

专利信息

专利号:US-2017267706-A1
优先权日:2014-08-19
标 题:Method for the synthesis of heterocyclic hydrogen phosphine oxide
发明人：BRUYNEEL FREDERIC; NOTTE PATRICK PIERRE
权利人:STRAITMARK HOLDING AG
摘要:A method for the synthesis of a heterocyclic hydrogen phosphine oxide, having the general formula: n n n n n n n n n n wherein:n nR is a aliphatic or aromatic divalent group optionally including one or more heteroatoms and optionally having one or more substituents andn nX and Y are independently selected from —O—, —C(O)O— and —NR′—n nwherein R′ is a monovalent group optionally having one or more heteroatoms including the steps of:n na) forming a reaction mixture by mixing a compound having the general formula HX—R—YH and tetraphosphorus hexaoxide; andn nb) recovering the resulting compound comprising the heterocyclic hydrogen phosphine oxide.

专利号:US-9181237-B2
优先权日:2013-10-04
标 题 :Substituted berbines and their synthesis
发明人：GROTE CHRISTOPHER W
权利人:MALLINCKRODT LLC
摘要:The present invention provides substituted berbines, processes for the synthesis of substituted berbine compounds, as well as intermediates used in the synthesis of substituted berbine compounds. Also provided are methods for using the substituted berbines to inhibit cancer cell growth.

专利号:US-6096900-A
优先权日:1999-05-07
标 题 :Solventless preparation of phthalimides
发明人：NICK ROBERT JOSEPH; NELSON MARK ERIK; CARINGI JOSEPH JOHN; WILLIAMS DREW ELLIOT
权利人:GEN ELECTRIC
摘要:A method for the solventless synthesis of a phthalimide or phthalimide mixture is provided comprising contacting at least one amine reactant and at least one anhydride reactant in a solventless environment at a first temperature sufficient to allow the reactants to at least partially condense; and increasing the temperature to a second temperature sufficient to melt the reaction mixture, thereby allowing the reaction to go essentially to completion and form the reaction product.

专利号:EP-1599438-B1
优先权日:2003-02-04
标题 :Preparation of substituted phthalic anhydride, especially 4-chlorophtalic anhydride
发明人：ODLE ROY RAY; GUGGENHEIM THOMAS LINK
权利人:GEN ELECTRIC
摘要:A method for the synthesis of substituted phthalic anhydrides (IV) wherein R' is a halogen, aromatic or aliphatic group comprising 1-18 carbons, hydrogen or nitro group is the transimidation between a substituted N-alkyl phthalimide (V) wherein R is an alkyl having from 1 to 18 carbons, and a substituted tetrahydrophthalic anhydride (VI): The by product of this reaction, a substituted N-alkyl tetrahydrophthalimide (VII), may be converted by aromatization to the substituted N-alkyl phthalimide (V).

专利号:US-11220480-B2
优先权日:2016-12-31
标题 :Synthesis of reactive intermediates for polyetherimides, and uses thereof
发明人：GUGGENHEIM THOMAS LINK; CHIONG HENDRICH; QUEVEDO SANCHEZ BERNABE; MISIEGO ARPA CARMEN ROCIO; RODRIGUEZ ORDONEZ JUAN JUSTINO; NIEVES REMACHA JAVIER
权利人:SHPP GLOBAL TECH BV
摘要:A method for producing a reactive intermediate composition, including: reacting a substituted phthalic anhydride of the formula (I) with a diamine of the formula H 2 N—R—NH 2 in the presence of an aromatic dianhydride in an amount of 10 to 50 mole percent based on the total moles of anhydride functionality in the reaction; wherein the reacting is conducted in an aprotic solvent in a reactor, under conditions effective to produce the reactive intermediate composition; and wherein X comprises a halogen or a nitro group, and R comprises a C 6-36 aromatic hydrocarbon group or a halogenated derivative thereof, a straight or branched chain C 2-20 alkylene or a halogenated derivative thereof, or a C 3-8 cycloalkylene or a halogenated derivative thereof.

专利号:US-6528663-B1
优先权日:2001-12-05
标 题 :Methods for the preparation of 4-chlorophthalic anhydride
发明人：ODLE ROY RAY; GUGGENHEIM THOMAS LINK
权利人:GEN ELECTRIC
摘要:A method for the synthesis of substituted phthalic anhydrides (IV) n wherein R′ is a halogen, aromatic or aliphatic group comprising 1-18 carbons, hydrogen or nitro group is the transimidation between a substituted N-alkyl phthalimide (V) n wherein R is an alkyl having from 1 to 18 carbons, and a substituted tetrahydrophthalic anhydride (VI): n The by-product of this reaction, a substituted N-alkyl tetrahydrophthalimide (VII), may be converted by aromatization to the substituted N-alkyl phthalimide (V).