CAS: 128249-70-7; 2,6-Bis((R)-4-Phenyl-4,5-Dihydrooxazol-2-yl)Pyridine

上下游产品

CAS号3739-94-4 2,6-吡啶二甲酰氯 | CAS号56613-80-0 D-苯甘氨醇 | CAS号661464-60-4 N,N'-bis[(1R)-2... | CAS号5431-44-7 2,6-吡啶二甲醛 | CAS号5453-67-8 2,6-吡啶二甲酸二甲酯 | CAS号499-83-2 2,6-吡啶二羧酸

吡啶-2.6-二羧酸二甲酯置于三乙胺,对甲苯磺酰氯体系中,用 二氯甲烷 用作溶剂,化学反应 36.0H,反应生成2,6-二[(4R)-4-苯基-2-恶唑啉基]吡啶
参考文献:Asymmetric Catalysis In A Micro Reactor-ce,Yb And Lu Catalysed Enantioselective Addition Of Trimethylsilyl Cyanide To Benzaldehyde
标题:Asymmetric Catalysis In A Micro Reactor-ce,Yb And Lu Catalysed Enantioselective Addition Of Trimethylsilyl Cyanide To Benzaldehyde
摘要:A T-Shaped Micro Reactor Was Used For The Optimisation Of Reaction Conditions For The Enantioselective Silyleyanation Of Benzaldehyde Catalysed By Lanthanide-Pybox Complexes. Compared To A Conventional Batch Procedure,Higher Conversion Was Observed Within Shorter Reaction Time. The Micro Reactor Process Involving Lu(III) Afforded Essentially The Same Enantioselectivity As The Batch Process (73 Vs 76% Ee),Whereas The Enantioselectivity Was Lower In The Micro Reactor For Catalysts Containing Yb(III) (53 Compared To 72%). Ce(III) Provided Very Low Selectivity In Both Types Of Processes (1 And 11 % Ee,Respectively). A Study Of The Effect Of Additives Showed That The Enantioselectivity In The Yb Catalysed Reaction Performed In The Micro Reactor Could Be Increased To 66%,Whereas Only A Minor Improvement,To 78% Ee,Was Observed In The Reaction With Lu. (C) 2004 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tet.2004.08.080

专利信息

专利号:US-11926589-B2
优先权日:2019-07-09
标 题 :Process for the synthesis of non-racemic cyclohexenes
发明人：REISMAN SARAH; ROMBOLA MICHAEL; LADD CAROLYN L; MCLAUGHLIN MARTIN JOHN; ZUEND STEPHAN; GOETZ ROLAND
权利人:BASF CORP; CALIFORNIA INST OF TECHN
摘要:This invention relates to a process for the synthesis of a non-racemic cyclohexene compound of formula (I) by a Diels-Alder reaction of a compound of formula (II) with a compound of formula (III) wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 and Y have the meanings as defined in the description in the presence of a catalyst comprising at least one m-valent metal cation M m+ wherein the metal M is selected from Scandium (Sc), Yttrium (Y), Lanthanum (La), Cerium (Ce), Praseodymium (Pr), Neodymium (Nd), Promethium (Pm), Samarium (Sm), Europium (Eu), Gadolinium 15 (Gd), Terbium (Tb), Dysprosium (Dy), Holmium (Ho), Erbium (Er), Thulium (Tm), Ytterbium (Yb), Lutetium (Lu), Gallium (Ga) and Indium (In), and m is an integer of 1, 2 or 3, and a chiral ligand of the formula (IV) wherein R 10a , R 10b , R 10c , R 10d , R 10a′ , R 10b′ , R 10c′ , R 10d′ , Z and Z′ have the meanings as defined in the description.

专利号:US-8431745-B2
优先权日:2006-03-29
标题 :Process for preparation of HIV protease inhibitors
发明人：CRAWFORD KENNETH R; DOWDY ERIC D; GUTIERREZ ARNOLD; POLNIASZEK RICHARD P; YU RICHARD HUNG CHIU
权利人:CRAWFORD KENNETH R; DOWDY ERIC D; GUTIERREZ ARNOLD; POLNIASZEK RICHARD P; YU RICHARD HUNG CHIU; GILEAD SCIENCES INC
摘要:A process for the synthesis of bisfuran intermediates useful for preparing antiviral HIV protease inhibitor compounds is hereby disclosed.

专利号:WO-2021007141-A1
优先权日:2019-07-09
标 题 :Process for the synthesis of non-racemic cyclohexenes

专利号:US-2022267247-A1
优先权日:2019-07-09
标题:Process for the synthesis of non-racemic cyclohexenes

专利号:US-11459287-B1
优先权日:2021-10-06
标题 :Arene-immobilized ru(II)TsDPEN complexes: synthesis and applications to the asymetric transfer hydrogenation of ketones
发明人：ALSHAIKH HIND FAISAL; KNIGHT JULIAN
权利人:UNIV KING ABDULAZIZ
摘要:Arene-immobilized Ru(II)TsDPEN Noyori-Ikariya catalysts anchored to silica through the coordinated η6-arene are provided. The catalysts efficiently catalyze many reactions, including the asymmetric transfer hydrogenation of ketones to alcohols.

专利号:EP-3997082-A1
优先权日:2019-07-09
标 题 :Process for the synthesis of non-racemic cyclohexenes