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CAS号884494-95-5 5-甲基-3-羧酸氯吡啶 | CAS号3222-49-9 5-甲基烟酸 | CAS号591-22-0 3,5-二甲基吡啶 | CAS号20826-02-2 5-甲基烟酸乙酯 | CAS号455-70-9 5-氟吡啶-3-甲酸甲酯 | CAS号407-21-6 3-氟-5-甲基吡啶 | CAS号3430-19-1 3-氨基-5-甲基吡啶 | CAS号42885-14-3 3-氰基-5-甲基吡啶 | CAS号39891-04-8 5-氟吡啶-3-甲醛 | CAS号402-66-4 5-氟烟酸 | CAS号22620-32-2 (5-氟吡啶-3-基)甲醇3,5-二甲基吡啶置于manganese(Iv) Oxide,氧气,尿素体系中,150.0 °C,506.66 Kpa 条件下,反应 4.0H,以80%的收率获得产物5-甲基烟酰氨
参考文献:锰代用品使氧化锰促进甲基芳烃的液相好氧氧化酰胺化为单酰胺
标题:锰代用品使氧化锰促进甲基芳烃的液相好氧氧化酰胺化为单酰胺
摘要:在无定形mno 2的存在下,各种甲基芳烃(即使具有两个或多个甲基)也可以以中等至高收率选择性地转化为相应的伯单酰胺.观测到的催化确实是非均相的,并且所回收的无定形mno 2催化剂可以重复使用而其催化性能没有明显损失.
DOI:10.1002/anie.201203098
专利信息
专利号:US-7612064-B2
优先权日:2003-05-26
标题:Sulfopyrroles
发明人:EBERLE MARTIN; ERMERT PHILIPP; OBRECHT DANIEL; LACH FRANK; LUTHER ANATOL; BACHMANN FELIX; STREBEL ALLESSANDRO
权利人:TAKEDA PHARMACEUTICAL
摘要:The invention relates to compounds of formula (I) wherein R 1 represents aryl, aralkyl or heteroaryl, R 2 is aryl or heteroaryl and R 3 is aryl, heteroaryl or optionally substituted aminomethyl, to methods of synthesis of such compounds, to pharmaceutical compositions containing compounds of formula (I), to the use of a compounds of formula (I) for the preparation of a pharmaceutical composition for the treatment of neoplastic and autoimmune diseases, and to methods of treatment of neoplastic and autoimmune diseases using compounds of formula (I) or of pharmaceutical compositions containing same.
专利号:US-8372971-B2
优先权日:2004-08-25
标 题:Heterocyclic compounds and methods of use
发明人:WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
权利人:TARGEGEN INC; WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
摘要:Heterocyclic compounds derived from benzotriazine, triazines, triazoles and oxadiazoles are disclosed. The methods of synthesis and of use of such heterocyclic compounds are also provided.
专利号:WO-2014063189-A1
优先权日:2012-10-23
标题 :Methods and products for preventing and/or treating a stress induced cardiomyopathy
发明人:HOROWITZ JOHN; CHIRKOV YULIY
权利人:ADELAIDE RES & INNOVATION PTY
摘要:The present disclosure relates to methods and products for preventing and/or treating a stress- induced cardiomyopathy. Certain embodiments of the present disclosure provide a method of preventing and/or treating a stress-induced cardiomyopathy in a subject, the method comprising administering to the subject a therapeutically effective amount of one or more of the following agents: a peroxynitrite inhibitor; an inhibitor of peroxynitrite synthesis; an inhibitor of peroxynitrite associated signalling; an inhibitor of peroxynitrite-induced DNA damage; a Tx NIP inhibitor; a beta 2 adrenoceptor antagonist; and a beta 3 adrenoceptor antagonist; thereby preventing and/or treating the stress-induced cardiomyopathy in the subject.