CAS: 88-68-6; 2-Aminobenzamide

• 英文名称2-Aminobenzamide
• 中文名称2-氨基苯甲酰胺
• IUPAC名称2-aminobenzamide
• 其它别名邻氨基苯甲酰胺; 2氨基苯甲酰胺; 2-Aminobenzamide; 2-Aminobenzenecarboxamide; 2-Carbamoylaniline; Anthranilamide; Anthranilimidic Acid; Nsc 38768; Sr 4327; O-Aminobenzamide; Anthranilic Acid Amide
• CAS编号88-68-6
• MFCD编号:MFCD00007981
• EINECS号:201-851-2
• FDA UNII编号:Q1M2WEK6VA
• 分子式:C7H8N2O
• 分子量:136.15
• 产品CID: 1904786
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• 产品信息参考;;;;
• InChIKey: PXBFMLJZNCDSMP-UHFFFAOYSA-N
• InChI=1S/C7H8N2O/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H2,9,10)…
• 计算化学: 氢键受体数2.0氢键供体数2.0可旋转键数1.0

物理性质

• 熔点111-113°C
• 沸点300.9°C at 760 mmHg
• 闪点198°C
• 密度1.2±0.1 g/cm3
• pKa:15.77±0.50(预测)
• PSA:69.11
• LogP:0.3677
• 折射率1.633
• 蒸汽压0.0±0.6 mmHg at 25°C
• 溶解性<5G/l
• 敏感性1.对眼睛有刺激性，避免吸入本品的粉尘，避免与眼睛及皮肤接触。
• 外观形态浅棕色至灰棕色结晶粉末或薄片状物
• 储存条件请置于阴暗处, 惰性气氛中,室温
• 产品应用该化合物用于油脂,润滑油和不饱和橡胶的抗氧化剂.

MSDS等安全信息

• GHS象形图
• GHS符号GHS05;
  注释: Corrosion
• 危险类别严重眼损伤 类别1
  急性毒性 类别4(经口)
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
  呼吸道致敏 类别1
  皮肤致敏 类别1
  严重眼刺激 类别2A
• 警示词Danger(危险)
• 危险描述H318 |造成严重眼损伤.
  H302 |吞咽有害.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H334 |吸入可能引起过敏或哮喘症状或呼吸困难.
  H317 |可能引起皮肤过敏反应.
• 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
• 危险等级IRRITANT
• UN编号NONH for all modes of transport
• 危险品标志Xn,Xi
• 安全声明26-36/37
• 危险类别码22-36/37/38-43
• WGK Germany1

欧盟法规

上下游产品

合成工艺路线路线简述

• 1885-29-6 = 88-68-6
  反应条件:1.1 Reagents: Water Catalysts: 2853616-75-6 Solvents: Isopropanol; 2 H,80 °C
  标题:Hydration Of Nitriles Catalyzed By Ruthenium Complexes: Role Of Dihydrogen Bonding Interactions In Promoting Base-Free Catalysis
  作者:Yadav,Samanta; Gupta,Rajeev
  参考文献:Inorganic Chemistry 日期:2022 卷标:61(39) 页码:15463-15474]
  
  610-15-1 = 88-68-6
  反应条件:1.1 Reagents: Hydrogen Catalysts: Cobalt (Nanoparticle Supported On Ordered Mesoporous Carbon) Solvents: 2-Methyltetrahydrofuran,Water; 20 Bar,Rt -> 40 °C; 24 H,20 Bar,40 °C
  标题:Superior Activity And Selectivity Of Heterogenized Cobalt Catalysts For Hydrogenation Of Nitroarenes
  作者:Li,Wu; Artz,Jens; Broicher,Cornelia; Junge,Kathrin; Hartmann,Heinrich; Et Al
  参考文献:Catalysis Science & Technology 日期:2019 卷标:9(1) 页码:157-162]
  
  615-43-0 = 88-68-6
  反应条件:1.1 Reagents: Ammonium Bicarbonate Catalysts: Palladium,Bis(Acetonitrile)Dichloro-,1,1′-(9,9-Dimethyl-9H-Xanthene-4,5-Diyl)Bis[1,1-Diphenylphosphine] Solvents: Acetonitrile; 3 H,1 Mpa,120 °C
  标题:Aminocarbonylation Of Aryl Halides To Produce Primary Amides By Using Nh4Hco3 Dually As Ammonia Surrogate And Base
  作者:Wang,Dong-Liang; Liu,Huan; Yang,Da; Wang,Peng; Lu,Yong; Et Al
  参考文献:Chemcatchem 日期:2017 卷标:9(22) 页码:4206-4211]
  
  610-15-1 = 88-68-6
  反应条件:1.1 Reagents: Hydrogen,Ammonia Catalysts: Iron Oxide (Fe2O3) (Complexes With Phenanthroline,N-Doped Graphene) Solvents: Methanol,Water; 30 H,30 Bar,90 °C
  标题:Fe2O3/ngr@c- And Co-Co3O4/ngr@c-Catalysed Hydrogenation Of Nitroarenes Under Mild Conditions
  作者:Formenti,Dario; Topf,Christoph; Junge,Kathrin; Ragaini,Fabio; Beller,Matthias
  参考文献:Catalysis Science & Technology 日期:2016 卷标:6(12) 页码:4473-4477]
  
  612-24-8 = 88-68-6
  反应条件:1.1 Reagents: Sodium Borohydride Catalysts: Gold (Zno-Supported) Solvents: Methanol; Rt; 1 H,Rt
  标题:Development Of Easily Separable Zno-Supported Au Nanocatalyst For The Oxidative Esterification Of Alcohols And Reduction Of Nitroarenes
  作者:Galani,Sunil M.; Giri,Arnab K.; Ghosh,Subhash C.; Panda,Asit B.
  参考文献:Chemistryselect 日期:2018 卷标:3(32) 页码:9414-9421]
  
  1885-29-6 = 88-68-6
  反应条件:1.1 Catalysts: Manganese Oxide (Mno2) Solvents: Isopropanol,Water; 40 Min,100 Psi,100 °C
  标题:Mild And Selective Heterogeneous Catalytic Hydration Of Nitriles To Amides By Flowing Through Manganese Dioxide
  作者:Battilocchio,Claudio; Hawkins,Joel M.; Ley,Steven V.
  参考文献:Organic Letters 日期:2014 卷标:16(4) 页码:1060-1063]
  
  612-24-8 = 88-68-6
  反应条件:1.1 Reagents: α-D-Glucose,Potassium Carbonate Solvents: Water; 3 H,100 °C
  标题:Glucose As An Eco-Friendly Reductant In A One-Pot Synthesis Of 2,3-Dihydroquinazolin-4(1H)-Ones
  作者:Dos Santos,Thiago; Grundke,Caroline; Lucas,Tobias; Grossmann,Luca; Clososki,Giuliano Cesar; Et Al
  参考文献:European Journal Of Organic Chemistry 日期:2020 卷标:2020(41) 页码:6429-6432]
  
  21563-73-5 + 75-12-7 = 88-68-6
  反应条件:1.1 5 - 6 H,Rt -> 120 °C; 120 °C -> Rt1.2 Reagents: Water; Rt
  标题:Formamide As An Ammonia Synthon In Amination Of Acid Chlorides
  作者:Srinivasan,S.; Manisankar,P.
  参考文献:Synthetic Communications 日期:2010 卷标:40(23) 页码:3538-3543]
  
  610-15-1 = 88-68-6
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Ethanol,Water; 9 H,40 °C
  标题:Effect Of The Structure Of Nitroarenes On Their Reduction By Brewers' Yeast (Saccharomyces Cerevisiae)
  作者:Begunov,R. S.; Kosareva,T. N.; Orlov,V. U.
  参考文献:Izvestiya Vysshikh Uchebnykh Zavedenii 日期:2005 卷标:48(11) 页码:56-57]
  
  4403-69-4 = 88-68-6
  反应条件:1.1 Reagents: Potassium Hydroxide Catalysts: 2506117-64-0 Solvents: Dimethyl Sulfoxide; 48 H,80 °C
  标题:A New Facet Of Amide Synthesis By Tandem Acceptorless Dehydrogenation Of Amines And Oxygen Transfer Of Dmso
  作者:Nie,Xufeng; Wang,Mei; Fu,Yihua; Xu,Jiaqi; Zheng,Xueli; Et Al
  参考文献:Journal Of Catalysis 日期:2023 卷标:417 页码:153-163]
  
  610-15-1 = 88-68-6
  反应条件:1.1 Reagents: Carbon Monoxide Catalysts: Rhodate(1-),Penta-μ-Carbonyldecacarbonylpenta-,(9Rh-Rh) Solvents: Toluene,Water; 10 H,10 Atm,80 °C
  标题:Selective Synthesis Of Rh5 Carbonyl Clusters Within A Polyamine Dendrimer For Chemoselective Reduction Of Nitro Aromatics
  作者:Maeno,Zen; Mitsudome,Takato; Mizugaki,Tomoo; Jitsukawa,Koichiro; Kaneda,Kiyotomi
  参考文献:Chemical Communications (Cambridge 日期:2014 卷标:50(49) 页码:6526-6529]
  
  1885-29-6 = 88-68-6
  反应条件:1.1 Reagents: Water Catalysts: Cesium Carbonate Solvents: Water; 30 Min,150 °C
  标题:Efficient And Practical Transition Metal-Free Catalytic Hydration Of Organonitriles To Amides
  作者:Tu,Tao; Wang,Zhixun; Liu,Zelong; Feng,Xike; Wang,Qingyi
  参考文献:Green Chemistry 日期:2012 卷标:14(4) 页码:921-924]
  
  552-89-6 = 88-68-6
  反应条件:1.1 Reagents: Urea,Oxygen Catalysts: Trifluoroacetic Acid,Cupric Acetate Solvents: Dimethyl Sulfoxide; 6 - 12 H,110 °C1.2 Reagents: Hydrazine Hydrate (1:1); < 1 Min,110 °C
  标题:Copper-Catalyzed One-Pot Synthesis Of Quinazolinones From 2-Nitrobenzaldehydes With Aldehydes: Application Toward The Synthesis Of Natural Products
  作者:Sahoo,Subrata; Pal,Shantanu
  参考文献:Journal Of Organic Chemistry 日期:2021 卷标:86(24) 页码:18067-18080]
  
  612-24-8 = 88-68-6
  反应条件:1.1 Reagents: Sodium Borohydride Catalysts: Nickel Dihydroxide (Two-Layer Mwcnt Nanohybrid With Photopolymerized Danta And Polycationic Pdadmac) Solvents: Tetrahydrofuran,Water; 10 Min,Rt1.2 4 H,Rt
  标题:Selective Conversion Of Nitroarenes To N-Aryl Hydroxylamines Catalysed By Carbon-Nanotube-Supported Nickel(Ii) Hydroxide
  作者:Prakash,Praveen; De Masi,Deborah; Geertsen,Valerie; Miserque,Frederic; Li,Haiyan; Et Al
  参考文献:Chemistryselect 日期:2017 卷标:2(21) 页码:5891-5894]
  
  612-24-8 = 88-68-6
  反应条件:1.1 Reagents: Hydrazine Hydrate (1:1) Catalysts: Nickel Solvents: Ethanol
  标题:Cyclic Amidines. Ix. Tricycloquinazoline
  作者:Butler,K.; Partridge,M. W.
  参考文献:Journal Of The Chemical Society 日期:1959 卷标:2396 页码:2396-400]
  
  117576-29-1 = 88-68-6
  反应条件:1.1 Reagents: Ammonium Hydroxide Solvents: Tetrahydrofuran; 2 H,0 °C
  标题:A New Protocol For The Synthesis Of Primary,Secondary And Tertiary Anthranilamides Utilizing N-(2-Aminoarylacyl)Benzotriazoles
  作者:Kaniskan,Nevin; Kokten,Sule; Celik,Ilhami
  参考文献:Arkivoc (Gainesville 日期:2012 卷标:(8) 页码:198-213]
  
  1885-29-6 = 88-68-6
  反应条件:1.1 Reagents: Methanesulfonic Acid Catalysts: Alumina; 120 °C; 15 Min,120 °C
  标题:A Facile Hydration Of Nitriles Into Amides By Al2O3/meso3H (Ama)
  作者:Sharghi,Hashem; Sarvari,Mona Hosseini
  参考文献:Synthetic Communications 日期:2003 卷标:33(2) 页码:207-212]
  
  118-48-9 = 88-68-6
  反应条件:1.1 Reagents: Ammonium Carbonate Solvents: 1,4-Dioxane; 8 H,60 °C
  标题:Synthesis And Nematicidal Activities Of 1,2,3-Benzotriazin-4-One Containing 4,5-Dihydrothiazole-2-Thiol Derivatives Against Meloidogyne Incognita
  作者:Chen,Xiulei; Zhou,Zhen; Li,Zhong; Xu,Xiaoyong
  参考文献:Phosphorus 日期:2020 卷标:195(3) 页码:194-200]
  
  118-48-9 = 88-68-6
  反应条件:1.1 Reagents: Ammonium Carbonate Solvents: 1,4-Dioxane; 5 - 8 H,60 °C
  标题:Synthesis And Nematicidal Activities Of 1,2,3-Benzotriazin-4-One Derivatives Against Meloidogyne Incognita
  作者:Wang,Gaolei; Chen,Xiulei; Deng,Yayun; Li,Zhong; Xu,Xiaoyong
  参考文献:Journal Of Agricultural And Food Chemistry 日期:2015 卷标:63(31) 页码:6883-6889]
  
  1885-29-6 = 88-68-6
  反应条件:1.1 Catalysts: Amberlyst A 26Oh Solvents: Ethanol,Water; 2 H,50 - 60 °C
  标题:Amberlyst A26 Oh As A Recyclable Catalyst For Hydration Of Nitriles And Water-Based Synthesis Of 4(1H)-Quinazolinones From 2-Aminobenzonitrile And Carbonyl Compounds
  作者:Tamaddon,Fatemeh; Pouramini,Farzaneh
  参考文献:Synlett 日期:2014 卷标:25(8) 页码:1127-1131

海关参考信息

• 2912110000-甲醛
  2912210000-苯甲醛
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

专利信息

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管