CAS: 101-53-1; 4-Benzylphenol

该化合物是一种有机化合物,其特征是其酚结构,由一种苯环取代,在段落位置上,以氢氧基组(-OH)和苯基组 (-C6H5CH2)为替代,该化合物以白到光黄色固态的形式出现,以其在水中的中中溶解性而著称,同时在有机溶剂中更易溶解;该产品具有酚的典型特性,包括作为抗氧化剂和潜在抗微生物剂的能力. 4-苯酚在各种应用中被使用,包括在合成其他化学化合物,生产树脂和塑料中作为中间体,其化学再活性受到可参与氢联结并影响其物理特性的氢氧组的存在的影响.安全数据表明,应当谨慎处理,因为它可能会引起接触时对皮肤和眼睛的刺激.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号1262139-41-2 Benzene, 1-(phe... | CAS号106-41-2 对溴苯酚 | CAS号53317-09-2 B-苄基-9-硼杂双环[3.3.1]壬烷 | CAS号100-51-6 苯甲醇 | CAS号108-95-2 苯酚 | CAS号1137-42-4 4-羟基二苯甲酮 | CAS号1211394-76-1 (4-(methoxymeth... | CAS号81842-24-2 4-benzylcyclohe... | CAS号140-11-4 乙酸苄酯 | CAS号39720-27-9 4-(氯甲基)苯基乙酸酯 | CAS号98774-23-3 替米利芬 | CAS号100544-80-7 4-(cyclohexylme... | CAS号101-81-5 二苯甲烷 | CAS号101-71-3 地芬南 | CAS号31089-49-3 Phenol,2-chloro... | CAS号3178-23-2 Cyclohexane,1,1... | CAS号35883-78-4 3-(4-oxotetrali... | CAS号35672-52-7 Benzene,1-ethox... | CAS号13031-44-2 4-ACETOXYBENZOP... | CAS号37021-63-9 2-Nitro-4-benzy...

合成工艺路线路线简述

    (Benzyloxy)Benzene置于铜体系中,化学反应生成4-羟基二苯甲烷
    参考文献:Behaghel; Freiensehner,Chemische Berichte,1934,Vol. 67,P. 1368,1374
    标题:Behaghel; Freiensehner,Chemische Berichte,1934,Vol. 67,P. 1368,1374

    海关参考信息

    专利信息


    专利号:US-7674876-B2
    优先权日:2005-05-25
    标题:Synthesis of novel monomers containing the trifluorovinylidene group and the cyanato group and polymers thereof
    发明人:DREYER CHRISTIAN; BAUER MONIKA; IYER SURESH S; SMITH DENNIS W
    权利人:FRAUNHOFER GES FORSCHUNG; UNIV CLEMSON
    摘要:Novel hybrid monomers containing both the aryltrifluorovyinyloxyether-group (TFVE-group) and the cyanato-group, their synthesis, and the synthesis of polymers made from these new hybrid monomers are disclosed.

    专利号:US-5914431-A
    优先权日:1996-09-23
    标 题 :Cocatalysts for the synthesis of bisphenols
    发明人:FENNHOFF GERHARD
    权利人:BAYER AG
    摘要:The invention relates to the synthesis of bisphenols from monophenols and carbonyl compounds such as aldehydes and ketones using concentrated mineral acids such as hydrochloric acid and/or hydrogen chloride gas as acid catalysts and a mercaptan as cocatalyst, which is fixed by an ion pair bond to a matrix that is insoluble in the reaction medium.

    专利号:US-5698600-A
    优先权日:1995-10-24
    标题:Process for the production of bisphenols with the use of new cocatalysts
    发明人:WULFF CLAUS; FENNHOFF GERHARD; EITEL ALFRED
    权利人:BAYER AG
    摘要:The invention relates to the synthesis of bisphenols from monophenols and carbonyl compounds such as aldehydes and ketones with concentrated mineral acids such as hydrochloric acid and/or hydrogen chloride gas as acid catalysts and a mercaptan as cocatalyst, which is fixed by an ion-pair bond to a matrix insoluble in the reaction medium.

    专利号:US-2005080260-A1
    优先权日:2003-04-22
    标 题 :Preparation of prodrugs for selective drug delivery
    发明人:MILLS RANDELL L; WU GUO-ZHANG
    摘要:Synthesis of a chemical compound having the formula A-B-C that may serve for applications such as drug delivery where A is a chemiluminescent, moiety, B is a photochromic moiety, and C is a biologically active moiety where A-B-C may serve as a prodrug. Novel synthetic methods of the present invention to form the prodrug comprised the steps of (1) forming a benzophenone, (2) forming a diaryl ethylene, (3) attaching a phthalimide moiety to at least one of the aryl groups of the ethylene to form a phthalimide-ethylene conjugate, (4) condensing two ethylene-phthalimide conjugates to form a phthalimide-pentadiene conjugate, (5) converting the phthalimide to the phthalhydrazide by reaction with hydrazine to form a carrier compound according to the present invention, and (6) reacting the carrier compound with an nucleophilic moiety of the drug to form the corresponding prodrug. Alternatively the carrier can be prepared by using the halo-substituted diaryl ethylene to make the corresponding cationic leuco dye-like compound with known methods. The cationic compound then is protected by reacting with a nucleophile and coupled with the aminophathalimide by palladium-catalyzed amination to form the protected phthalimide-pentadiene conjugate. The latter is refluxed with hydrazine to convert its phthalimide to the phthalhydrazide and acidified to give the carrier. An additional aspect of the present invention relates to the use of these compounds as antiviral agents for the treatment of viral infections such as HIV and as anticancer agents for the treatment of cancers such as bowel, lung, and breast cancer.

    专利号:EP-0377198-A2
    优先权日:1988-12-31
    标题:Chloroformiates of aromatic ketones, and process for their preparation
    发明人:BOETTCHER ANDREAS DR; HENKELMANN JOCHEM DR
    权利人:BASF AG
    摘要:The invention relates to chloroformates of aromatic ketones and their preparation from aromatic hydroxyketones by phosgenation in the presence of acidic catalysts.n n n The chloroformates according to the invention are intermediates for the synthesis of organic compounds.

    专利号:US-2001046938-A1
    优先权日:2000-03-04
    标 题:Synthesis of dilithium initiator
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    合成参考文献


    摘要:Wicha, J., Science of Synthesis, (2009) 48, 110.
    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2014) 4, 84.
    摘要:González-Bello, C., Science of Synthesis Knowledge Updates, (2018) 1, 211.
    摘要:Kelly, C. B.; Matsui, J. K.; Phelan, J. P.; Gutiérrez Bonet, Á.; Lang, S. B.; Molander, G. A., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 342.
    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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