专利号:US-2024239737-A1 优先权日:2023-01-13 标题 :Synthesis of Triisoamyl Citrate (Triisopentanol) and its Applications as a Solvent, Plastizer and Component of Cosmetic and Aerosol Formulations 发明人:SATO SETSUO 权利人:BRASIL BIO FUELS S A 摘要:The present invention is based on the synthesis of triisoamyl citrate (triisopentanol citrate) and its applications as a plasticizer for polyvinyl chloride polymers, natural and synthetic rubbers, industrial solvents, replacing petrochemical-based products such as Phthalates (Dioctyl Phthalate, Diisononyl Phthalate, Dibutyl Phthalate), Acetylated tributylcitrate, epoxidized fatty esters, isoparaffins. It is a 100% renewable, high-performance, non-toxic, biodegradable product with an extremely competitive cost. With the increase in corn alcohol production in Brazil, this technology and product adds value to the fusel oil co-product generated in corn alcohol plants.
专利号:US-11745159-B2 优先权日:2017-10-20 标题:Heated nanowells for polynucleotide synthesis 发明人:MARSH EUGENE P; INDERMUHLE PIERRE F; PECK BILL JAMES 权利人:TWIST BIOSCIENCE CORP 摘要:Defined sequence RNA synthesis by 3′→5′ direction is now well established and currently in use for synthesis and development of vast variety of therapeutic grade RNA and Si RNA etc. A number of such synthetic RNA requires a modification or labeling of 3′-end of an oligonucleotide. The synthesis of 3′-end modified RNA requiring lipophilic, long chain ligands or chromophores, using 3′→5′ synthesis methodology is challenging, requires corresponding solid support and generally results in low coupling efficiency and lower purity of the final oligonucleotide in general because of large amount of truncated sequences containing desired hydrophobic modification. We have approached this problem by developing reverse RNA monomer phosphoramidites for RNA synthesis in 5′→3′-direction. They lead to very clean oligonucleotide synthesis allowing for introduction of various modifications at the 3′-end.
专利号:US-11512347-B2 优先权日:2015-09-22 标 题 :Flexible substrates for nucleic acid synthesis 发明人:PECK BILL JAMES 权利人:TWIST BIOSCIENCE CORP 摘要:Provided herein are compositions, devices, systems and methods for the generation and use of biomolecule-based information for storage. Further described herein are highly efficient methods for long term data storage with 100% accuracy in the retention of information. Additionally, devices described herein for de novo synthesis of oligonucleic acids encoding information related to the original source information may have a flexible material for oligonucleic acids extension.
专利号:US-7749300-B2 优先权日:2008-06-05 标题 :Photochemical synthesis of bimetallic core-shell nanoparticles 发明人:CHRETIEN MICHELLE N; WU YILIANG; CHOPRA NAVEEN 权利人:XEROX CORP 摘要:A method of forming bimetallic core-shell metal nanoparticles including a core of a first metal material and a shell of a second metal material, the method including photochemically producing metallic nanoparticle cores of the first metal material, and forming a shell of the second metal material around the cores. The shell can be formed by adding shell-forming precursor materials to a solution or suspension of the cores and photochemically forming the shells around the cores, or by separately photochemically producing metallic nanoparticles of the second metal material and mixing the metallic nanoparticles of the second metal material and the metallic nanoparticle cores to cause the metallic nanoparticles of the second metal material to form a shell around the metallic nanoparticle cores.
专利号:US-5662898-A 优先权日:1990-08-20 标 题 :Genes for the synthesis of antipathogenic substances 发明人:LIGON JAMES M; HILL DWIGHT STEVEN; LAM STEPHEN TING; HAMMER PHILIP E 权利人:CIBA GEIGY CORP 摘要:The present invention is directed to the production of an antipathogenic substance (APS) in a host via recombinant expression of the polypeptides needed to biologically synthesize the APS. Genes encoding polypeptides necessary to produce particular antipathogenic substances are provided, along with methods for identifying and isolating genes needed to recombinantly biosynthesize any desired APS. The cloned genes may be transformed and expressed in a desired host organisms to produce the APS according to the invention for a variety of purposes, including protecting the host from a pathogen, developing the host as a biocontrol agent, and producing large, uniform amounts of the APS.
专利号:US-8673260-B2 优先权日:2012-01-04 标 题 :Development of earth-abundant mixed-metal sulfide nanoparticles for use in solar energy conversion 发明人:PLASS KATHERINE 权利人:FRANKLIN AND MARSHALL COLLEGE 摘要:This invention relates to a process for the phase-controlled synthesis of ternary and quaternary mixed-metal sulfide nanoparticles by reacting soft metal ions with hard metal ions in a high-boiling organic solvent in the presence of a complexing and activating ligands to control the reactivity of the metal ions. Ternary and quaternary mixed metal sulfides nanoparticles of copper, sulfur, and iron, aluminum, tin, and silicon are preferred. This invention also relates to the phase controlled preparation of polymorphs of bornite nanoparticles and the phase controlled preparation of stabilized α- and γ-chalconite nanoparticles.
1: Santana-Mayor Á, Socas-Rodríguez B, Afonso MDM, Palenzuela-López JA, Rodríguez-Delgado MÁ. Reduced graphene oxide-coated magnetic-nanoparticles as sorbent for the determination of phthalates in environmental samples by micro-dispersive solid-phase extraction followed by ultra-high-performance liquid chromatography tandem mass spectrometry. J Chromatogr A. 2018 Jun 13. pii: S0021-9673(18)30773-8. doi: 10.1016/j.chroma.2018.06.031. [Epub ahead of print] doi: 10.1016/j.envpol.2018.05.089. [Epub ahead of print] doi: 10.1007/s10661-018-6665-8. doi: 10.1002/jssc.201800192. Epub 2018 May 14. doi: 10.1155/2018/9470254. eCollection 2018. 7: Salaudeen T, Okoh O, Agunbiade F, Okoh A. Fate and impact of phthalates in activated sludge treated municipal wastewater on the water bodies in the Eastern Cape, South Africa. Chemosphere. 2018 Jul;203:336-344. doi: 10.1016/j.chemosphere.2018.03.176. Epub 2018 Mar 28. doi: 10.1007/s11356-018-1845-1. Epub 2018 Mar 27. doi: 10.1007/s11356-018-1471-y. Epub 2018 Feb 22. doi: 10.1007/s10532-018-9822-4. Epub 2018 Feb 15. doi: 10.1016/j.chroma.2018.02.001. Epub 2018 Feb 6. doi: 10.1016/j.chemosphere.2017.11.163. Epub 2017 Nov 28. Review. doi: 10.1016/j.chroma.2017.11.013. Epub 2017 Nov 8. doi: 10.1016/j.fct.2017.11.005. Epub 2017 Nov 8. doi: 10.1016/j.scitotenv.2017.10.337. Epub 2017 Nov 8. doi: 10.1016/j.chemosphere.2017.10.066. Epub 2017 Oct 12. doi: 10.1016/j.chroma.2017.10.025. Epub 2017 Oct 10. doi: 10.1016/j.jchromb.2017.07.030. Epub 2017 Jul 18. doi: 10.1016/j.ultsonch.2017.03.051. Epub 2017 Mar 31.