CAS: 141091-37-4; 2-(Cyclohex-1-En-1-yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane

相似化合物

89490-05-1 865869-26-7 859217-67-7

上下游产品

CAS号28075-50-5 1-环状己烯三氟甲烷磺酸 | CAS号73183-34-3 双戊酰二硼 | CAS号2044-08-8 1-溴环己-1-烯 | CAS号17497-53-9 1-iod°Cyclohexene | CAS号25015-63-8 频那醇硼烷 | CAS号110-83-8 环己烯 | CAS号591-49-1 1-甲基-1-环己烯 | CAS号89490-05-1 环己烯-1-基硼酸 | CAS号1821-23-4 1-(1-cyclohexen... | CAS号224-11-3 [1,3]dioxolo[4,...

1-碘环己烯置于三乙胺,N,N-二甲基甲酰胺体系中,化学反应 25.0H,反应生成环己烯-1-硼酸频哪醇酯
参考文献:烷基和芳基碘化物的金属自由基硼化
标题:烷基和芳基碘化物的金属自由基硼化
摘要:介绍了在温和条件下以双(儿茶酚)二硼(b 2 Cat 2 )作为硼源对烷基碘化物和芳基碘化物进行金属自由基硼化反应.硼化反应操作简便,具有较高的官能团耐受性和广泛的底物范围.自由基时钟实验和密度泛函理论计算提供了对 B 2 Cat 2的 C 自由基硼化的机制和速率常数的见解.
Doi:10.1002/anie.201810782

专利信息

专利号:US-12319691-B2
优先权日:2020-05-04
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：CZABANIUK LARA C; HOPPER TIMOTHY; HOUZE JONATHAN B; RESCOURIO GWENAELLA; SANTORA VINCENT; WANG HAOXUAN; WHITE RYAN D; WONG ALICE R; WU YONGWEI
权利人:AMGEN INC; VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?).This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-12150934-B2
优先权日:2016-11-30
标 题 :Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases
发明人：SIDDIQUI ARSHAD M; CIBLAT STEPHANE; CONSTANTINEAU-FORGET LEA; GRAND-MAITRE CHANTAL; GUO XIANGYU; SRIVASTAVA SANJAY; SHIPPS GERALD W; COOPER ALAN B; OZA VIBHA; KOSTURA MATTHEW W; LUTHER MICHAEL; LEVINE JEDD
权利人:BANTAM PHARMACEUTICAL LLC
摘要:Disclosed are methods of treating hyperproliferative disorders such as cancer, methods of arresting the cell cycle in cancer cells, methods of inhibiting glutathione synthesis in cancer cells, and associated compounds for use and uses in medicaments. In certain embodiments, the methods, uses and compounds are provided with reference to compounds of the structural formula (I), in which X1, X2, Z1, Z2, the ring system denoted by “aâ€?, R1, L1, L2, Q, L3, R3, L4, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein are especially active against cancers having a mutant KRAS gene.

专利号:US-9839642-B2
优先权日:2014-05-09
标 题:Beta-tetrazolyl-propionic acids as metallo-beta-lactamase inhibitors
发明人：TANG HAIFENG; YANG SHU-WEI; MANDAL MIHIR; SU JING; LI GUOQING; PAN WEIDONG; TANG HAIQUN; DEJESUS REYNALDA; PAN JIANPING; HAGMANN WILLIAM; DING FA-XIANG; XIAO LI; PASTERNAK ALEXANDER; HUANG YUHUA; DONG SHUZHI; YANG DEXI
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula I that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.

专利号:CN-116283660-B
优先权日:2023-02-28
标题:Asymmetric synthesis method of chiral cyclopropane derivative

专利号:CN-116283660-A
优先权日:2023-02-28
标题:Asymmetric synthesis method of chiral cyclopropane derivative