CAS: 17110-51-9; Cholesterol Oleyl Carbonate

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15455-83-1 15455-82-0 23836-43-3

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CAS号143-28-2 油醇 | CAS号23836-43-3 胆固醇乙基碳酸酯 | CAS号57-88-5 胆固醇

胆固醇置于lipozyme Im,4 A Molecular Sieve体系中,60.0~80.0 °C,40.0 Kpa 条件下,反应 96.0H,反应生成胆固醇油醇碳酸酯
参考文献:Steryl And Stanyl Esters Of Fatty Acids By Solvent-Free Esterification And Transesterification In Vacuo Using Lipases From Rhizomucor Miehei,Candida Antarctica,And Carica Papaya
标题:Steryl And Stanyl Esters Of Fatty Acids By Solvent-Free Esterification And Transesterification In Vacuo Using Lipases From Rhizomucor Miehei,Candida Antarctica,And Carica Papaya
摘要:Sitostanol Has Been Converted In High To Near-Quantitative Extent To The Corresponding Long-Chain Acyl Esters Via Esterification With Oleic Acid Or Transesterification With Methyl Oleate Or Trioleoylglycerol Using Immobilized Lipases From Rhizomucor Miehei (Lipozyme Im) And Candida Antarctica (Lipase B,Novozym 435) As Biocatalysts In Vacuo (20-40 Mbar) At 80 Degreesc,Whereas The Conversion Was Markedly Lower At 60 And 40 Degreesc. Corresponding Conversions Observed With Papaya (Carica Papaya) Latex Lipase Were Generally Lower. High Conversion Rates,Observed In Transesterification Of Sitostanol With Methyl Oleate At 80 Degreesc Using Lipozyme Im Were Retained Even After 10 Repeated Uses Of The Biocatalyst. Saturated Sterols Such As Sitostanol And 5 Alpha-Cholestan-3 Beta-Ol Were The Preferred Substrates As Compared To Delta (5)-Unsaturated Cholesterol In Transesterification Reactions With Methyl Oleate Using Lipozyme Im. Transesterification Of Cholesterol With Dimethyl 1,8-octanedioate Using Lipozyme Im In Vacuo Yielded Methylcholesteryl 1,8-octanedioate (75%) And Dicholesteryl 1,8-octanedioate (5%). However,Transesterification. Of Cholesterol With Diethyl Carbonate And That Of Oleyl Alcohol With Ethylcholesteryl Carbonate,Both Catalyzed By Lipozyme Im,Gave Ethylcholesteryl Carbonate And Oleylcholesteryl Carbonate,Respectively,In Low Yield (20%). Moreover,Cholesterol Was Transesterified With Ethyl Dihydrocinnamate Using Lipozyme Im To Give Cholesteryl Dihydro Cinnamate In Moderate Yield (56%),Whereas The Corresponding Reaction Of Lanosterol Gave Lanosteryl Oleate In Low Yield (14%).
Doi:10.1021/jf0107407