CAS: 459-86-9; 2,2'-(Propane-1,2-Diylidene)Bis(Hydrazinecarboximidamide)

上下游产品

aminoguanidine bicarbonate 2-oxopropanal

氨基胍碳酸氢盐,丙酮醛置于硫酸体系中,化学反应生成 米托胍腙
参考文献:甲基乙二酸双(双胍)类似物的研究.二.甲基乙二酸双(双胍)的结构变化
标题:甲基乙二酸双(双胍)类似物的研究.二.甲基乙二酸双(双胍)的结构变化
摘要:
DOI:10.1021/jm00340A020

专利信息

专利号:US-2012129939-A1
优先权日:2009-02-26
标题:Polyamine inhibitors for the treatment and prevention of parkinson's disease
发明人：SMALL SCOTT A; LEWANDOWSKI NICOLE; LANDRY DONALD W; DENG SHI-XIANG
权利人:SMALL SCOTT A; LEWANDOWSKI NICOLE; LANDRY DONALD W; DENG SHI-XIANG
摘要:Disclosed herein are methods for treating a disease involving α-synucleic aggregation using (1) a compound which reduces the amount of polyamines in an amount effective to reduce α-synucleic aggregation; (2) a compound which inhibits polyamine synthesis in an amount effective to reduce α-synucleic aggregation; or (3) a compound which inhibits α-synucleic aggregation in an amount effective to reduce α-synucleic aggregation. Also disclosed are methods for reducing the amount of α-synucleic aggregation in a brain cell using (1) a compound which reduces the amount of polyamines in an amount effective to reduce α-synucleic aggregation; (2) a compound which inhibits polyamine synthesis in an amount effective to reduce α-synucleic aggregation; or (3) a compound which inhibits α-synucleic aggregation in an amount effective to reduce α-synucleic aggregation. Disclosed herein are also compounds which can be used in the above described methods.

专利号:US-4751348-A
优先权日:1983-07-16
标题:Nicotiana plants with both altered polyamine levels and flower structures and method for obtaining these plants
发明人：MALMBERG RUSSELL L; MCINDOO JEAN
权利人:COLD SPRING HARBOR LAB
摘要:Plant cell lines with altered flower structures, and altered plant male and/or female sterility/fertility, and altered polyamine synthesis have been isolated using a UV mutagenizing light, polyamine synthesis inhibitors, and growth in the dark. Some of these cell lines are resistant to MGBG and exhibit elevated polyamine synthesis. Regenerated plants with unusual flowers are thus possible as are crop and flower plants with unusual flowers, and/or altered fertility capability by the method of the invention. These plant lines are also useful as research tools.

专利号:CN-111170991-B
优先权日:2014-07-11
标题 :Antiproliferative compounds and methods of synthesis thereof