专利号:US-2012094919-A1 优先权日:2009-03-16 标题 :Use of tripeptides 发明人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO 权利人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO 摘要:The present invention relates to the use of tripeptide derivatives for tightening, firming and/or moisturizing skin. Furthermore, the invention relates to a method for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue and/or proteoglycans by fibroblasts and/or keratinocytes such as in particular the synthesis of Hyaluronic acid and/or of the proteoglycans Decorin and/or Lumican.
专利号:WO-9108220-A1 优先权日:1989-12-01 标 题:A method for the stepwise, controlled synthesis of chemical species, particularly peptides, coupled products obtained by the method and the use of these coupled products, e.g. as vaccines 发明人:HOUEN GUNNAR; HOLM ARNE 权利人:HOUEN GUNNAR; HOLM ARNE 摘要:Chemical species, particularly peptides, are synthesized by a stepwise, controlled process, in which a proteinaceous substance such as a protein is used as the synthesis substrate. The products obtained by the process can be used e.g. as vaccines against various diseases and as matrix materials or carrier molecules.
专利号:WO-0031134-A9 优先权日:1998-11-20 标题:Regulation of hair follicle morphogenesis based on beta-catenin 发明人:GAT URI; DASGUPTA RAMANUJ; DEGENSTEIN LINDA; FUCHS ELAINE 权利人:ARCH DEV CORP; GAT URI; DASGUPTA RAMANUJ; DEGENSTEIN LINDA; FUCHS ELAINE 摘要:The present invention provides a method for inducing hair growth by providing beta-catenin activity to a skin cell. This may be achieved by providing a beta-catenin polypeptide, providing a beta-catenin agonist, providing a polynucleotide encoding a beta-catenin polypeptide, enhancing the de novo synthesis of beta-catenin, increasing the stability or decreasing the degradation of beta-catenin polypeptides.
专利号:EP-1239813-B1 优先权日:1999-12-23 标题:Extract of blue-green alga spirulina and the use thereof in cosmetic skin-care and body care agents 发明人:SCHLOTMANN KORDULA; WALDMANN-LAUE MARIANNE; JASSOY CLAUDIA; KAETEN MELANIE; KOEHLER EVA-MARIA; PULZ OTTO; KURTH ELKE 权利人:HENKEL KGAA 摘要:The invention relates to an aqueous or aqueous-alcoholic extract of the blue-green algal taxon Spirulina, characterized in that it contains at least 10 wt. % magnesium in relation to the dry weight of said extract. The inventive blue-green alga extract is an efficacious component for stimulating intracellular synthesis of ATP and matrix proteins and differentiation of keratinozytes. The blue-green alga extract is used in topical preparations for cleaning and cosmetic care of the skin and hair, in addition to the production of agents for dermatological treatment of the skin.
专利号:US-6511832-B1 优先权日:1999-10-06 标题:In vitro synthesis of capped and polyadenylated mRNAs using baculovirus RNA polymerase 发明人:GUARINO LINDA A; DONG WEN; JIN JIANPING 权利人:TEXAS A & M UNIV SYS 摘要:The present invention relates to the use of baculovirus RNA polymerase for the production of capped and polyadenylated transcripts in vivo and especially in vitro. More particularly, the purified RNA polymerase of the present invention may be used to produce in vitro transcription and/or in vitro transcription/translation kits.
专利号:WO-2005079742-A1 优先权日:2004-02-19 标 题:Cosmetic and/or dermatological agent for increasing the endogenous lipid content of the skin 发明人:VEEGER MARCEL; KLOTZ ANDREAS; ZUR MUEHLEN ANNETTE; THOERNER BRIGITTE 权利人:STOCKHAUSEN CHEM FAB GMBH; VEEGER MARCEL; KLOTZ ANDREAS; ZUR MUEHLEN ANNETTE; THOERNER BRIGITTE 摘要:The invention relates to the use of at least one active ingredient that is selected from the water-soluble groups: (a) allantoin; (b) salts and/or esters of gluconic acid and/or aspartic acid; (c) precursors of creatine, creatine and creatinine and their derivatives; (d) glycyrrhetinic acid or the salts and/or esters thereof; (e) D-panthenol and/or at least one active ingredient that is selected from the oil-soluble groups: (f) vitamin E acetate; (g) cholesterol; (h) derivatives of glycyrrhetinic acid, in so far as they are soluble in the oils and fats that are conventionally used in the cosmetic industry; (i) vegetable oils and fats; (j) non-saponifiable fractions of vegetable fats. Said active ingredients are used alone or in combination with one or more active ingredients from the groups (a) to (j) to produce a cosmetic and/or dermatological agent for stimulating the endogenous synthesis of barrier substances, in particular for increasing the endogenous lipid content of the skin.
摘要:Lyman WJ et al; Handbook of Chemical Property Estimation Methods. Washington, DC: Amer Chem Soc pp. 7-4, 7-5, 8-12 (1990) 摘要: 摘要:Franke C et al; Chemosphere 29: 1501-14 (1994) 摘要:NTP/NIEHS; Short Term Reproductive and Developmental Toxicity of Bromochloroacetic Acid (CAS No. 5589-96-8) Administered in the Drinking Water to Sprague-Dawley Rats NTP Study Number: RDGT96001. NTIS#: PB98-172414 (August 1998). Abstract 摘要:NTP/NIEHS; TR-549 Toxicology and Carcinogenesis Studies of Bromochloroacetic Acid (CAS No. 5589-96-8) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) (Draft abstract).