专利号:US-9102708-B2 优先权日:2006-02-17 标 题:Methods for the synthesis of dicarba bridges in organic compounds 发明人:ROBINSON ANDREA JANE; JACKSON WILLIAM ROY; PATEL JIM; ELARIDI JOMANA 权利人:ROBINSON ANDREA JANE; JACKSON WILLIAM ROY; PATEL JIM; ELARIDI JOMANA; SYNGENE LTD 摘要:The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis.
专利号:US-8759480-B2 优先权日:2006-02-17 标题:Contoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides 发明人:ROBINSON ANDREA; ELARIDI JOMANA 权利人:ROBINSON ANDREA; ELARIDI JOMANA; SYNGENE LTD 摘要:According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.
专利号:US-2008227851-A1 优先权日:2007-03-12 标题 :Laulimalide and laulimalide analogs 发明人:WENDER PAUL A 权利人:WENDER PAUL A 摘要:Novel laulimalide analogs, methods for the treatment of proliferative disease and processes for the synthesis of laulimalide and novel laulimalide analogs are described.
专利号:US-2007197429-A1 优先权日:2006-02-17 标 题:Conotoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides
专利号:US-7745573-B2 优先权日:2006-02-17 标题:Conotoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides
专利号:US-2013123463-A1 优先权日:2006-02-17 标题:Methods for the synthesis of two or more dicarba bridges in organic compounds