CAS: 98-15-7; 3-Chlorobenzotrifluoride

上下游产品

CAS号98-88-4 苯甲酰氯 | CAS号98-17-9 3-三氟甲基苯酚 | CAS号98-08-8 三氟甲苯 | CAS号108-41-8 间氯甲苯 | CAS号98-16-8 间三氟甲苯胺 | CAS号401-81-0 3-碘三氟甲苯 | CAS号61841-46-1 2,3,5-Trichloro... | CAS号383-73-3 bis(trifluoroac... | CAS号108-90-7 氯苯 | CAS号328-84-7 3,4-二氯三氟甲苯 | CAS号320-50-3 2,5-二氯三氟甲苯 | CAS号54773-20-5 3,5-二氯三氟甲苯 | CAS号54773-19-2 2,3-二氯三氟甲苯 | CAS号56148-83-5 2,4,5-三氯三氟甲苯 | CAS号50594-82-6 3,4,5-三氯三氟甲苯 | CAS号61841-46-1 2,3,5-Trichloro... | CAS号454-90-0 间三氟甲基苯甲醚 | CAS号98-08-8 三氟甲苯 | CAS号325142-82-3 3-(三氟甲基)苯硼酸频哪醇酯

三氟甲苯置于氯,三氯化铁体系中,化学反应生成 间氯三氟甲苯
参考文献:Mcbee Et Al.,Journal Of The American Chemical Society,1947,Vol. 69,P. 946
标题:Mcbee Et Al.,Journal Of The American Chemical Society,1947,Vol. 69,P. 946

专利信息

专利号:US-6958420-B2
优先权日:2002-07-19
标题:Synthesis of aminoarylboronic esters and substituted anilines from arenes via catalytic C-H activation/borylation/amination and uses thereof
发明人：MALECZKA JR ROBERT E; SMITH III MILTON R; HOLMES DANIEL
权利人:UNIV MICHIGAN STATE
摘要:A process is described for synthesizing aminoarylboronic esters of the general formula n n nwherein R, R 2 , and R 3 are each an alkyl, aryl, vinyl, alkoxy, carboxylic esters, amides, or halogen; Ar is any variety of phenyl, naphthyl, anthracyl, heteroaryl; and R 1 is alkyl, hydrogen, or aryl. The aminoarylboronic esters are produced via the metal-catalyzed coupling of arylboronic esters of the general formula n n nwherein R and R 1 are any non-interfering group and X is chloro, bromo, iodo, triflates, or nonaflates to amines (primary and secondary). In particular, a process is described for the synthesis of the aminoarylboronic esters via a step-wise or tandem process in which one catalytic event is a metal-catalyzed borylation and the other catalytic event is a metal-catalyzed amination.

专利号:US-2013184465-A1
优先权日:2010-09-30
标 题:Process for the synthesis of thio-triazolo-group containing compounds
发明人：DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL
权利人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL; BASF SE
摘要:The present invention relates to a process using specific magnesium reagents for providing thio-triazolo group-containing compounds and for the synthesis of precursors therefor. The invention furthermore relates to intermediates and to their preparation.

专利号:US-6048991-A
优先权日:1990-11-16
标题:Preparation of epoxides
发明人：HAERMELING DIETER
权利人:BASF AG
摘要:Alpha-hydroxy-epoxides of alpha-alkoxy-epoxides of the formula IV ##STR1## in which the substituents have the following meanings: R 7 , R 8 , R 9 , R 10 , R 11 are independently hydrogen, C 1 -C 20 -alkyl, C 3 -C 12 -cycloalkyl, C 4 -C 20 -cycloalkylalkyl, C 1 -C 20 -hydroxy-alkyl, a heterocyclic ring, or an aryl or C 7 -C 20 -arylalkyl group optionally substituted by C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, halogen, C 1 -C 4 -haloalkyl, C 1 -C 4 -halo-alkoxy, phenyl, phenoxy, halophenyl, halophenoxy, carboxy, C 2 -C 8 -alkoxycarbonyl, or cyano, or R 7 and R 8 or R 7 and R 9 or R 7 and R 10 or R 9 and R 10 or R 10 and R 11 together form a (CH 2 ) n group in which n is an integer from 1 to 10 and which may be optionally substituted by C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, and/or halogen, and n R 12 is hydrogen, C 1 -C 8 -alkyl, or benzyl, n provided that R 10 is not hydrogen, methyl, ethyl, propyl, or cyclohexyl when R 7 , R 8 , R 9 , or R 11 is hydrogen, that R 7 is not methyl when R 8 is methyl or phenyl and R 9 , R 10 , or R 11 is hydrogen, that R 7 is not methyl when R 8 , R 9 , R 10 , or R 11 is hydrogen and R 12 is ethyl, that R 7 is not phenyl or hexyl when R 8 , R 9 , R 10 , or R 11 is hydrogen, that R 9 is not methyl when R 7 , R 8 , R 10 , or R 11 is hydrogen, that R 10 and R 11 are not methyl when R 7 , R 8 , or R 9 is hydrogen, and that R 7 and R 10 do not together form an unsubstituted cycloalkyl when R 8 , R 9 , or R 11 is hydrogen. The epoxides of the above formula serve as intermediates for the synthesis of, inter alia, perfumes, plant protectants and polymers.

专利号:WO-0021917-A1
优先权日:1998-10-13
标题 :Pharmaceutical intermediate for the synthesis of fluoxetine and a process for the preparation thereof
发明人：REITER JOZSEFNE; SIMIG GYULA; MEZEI TIBOR; IMRE JANOS; VERECZKEYNE DONATH GYOERGYI; NAGY KALMAN; NEMETH NORBERT; SZABO TIBOR
权利人:EGYT GYOGYSZERVEGYESZETI GYAR; REITER JOZSEFNE; SIMIG GYULA; MEZEI TIBOR; IMRE JANOS; VERECZKEYNE DONATH GYOERGYI; NAGY KALMAN; NEMETH NORBERT; SZABO TIBOR
摘要:The invention relates to N,N-dimethyl-{3-phenyl-3-[(4-trifluoromethyl)-phenoxy]-propyl-amine}-p-toluenesulfonate of Formula (I) and an improved process for the preparation thereof. The new compound of Formula (I) is a valuable pharmaceutical intermediate useful in the preparation of the antidepressant having the generic name fluoxetine.

专利号:US-2016073631-A1
优先权日:2013-03-04
标 题 :Process for the preparation of dihydropyrrole derivatives
发明人：EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

专利号:US-8114993-B2
优先权日:2007-02-06
标题:Use of aryl chlorides in palladium-catalyzed C-H bond functionalization
发明人：DAUGULIS OLAFS; CHIONG HENDRICH
权利人:DAUGULIS OLAFS; CHIONG HENDRICH; UNIV HOUSTON SYSTEM
摘要:A one-step method for efficiently converting carbon-hydrogen bonds into carbon-carbon bonds using chloroarenes and palladium catalysts is disclosed. This method allows faster introduction of complex molecular entities, a process that would otherwise require many more steps. This invention is particularly relevant for the organic synthesis of complex molecules such as, but not limited to, pharmacophores.