苯并呋喃-3-羧酸置于sodium Hydroxide,Aluminum Nickel体系中,化学反应生成氢化肉桂酸内酯 参考文献:Reductions With Nickel-Aluminum Alloy And Aqueous Alkali. Part Viii. Hydrogenolysis Of Furan Derivatives1 标题:Reductions With Nickel-Aluminum Alloy And Aqueous Alkali. Part Viii. Hydrogenolysis Of Furan Derivatives1 摘要: Doi:10.1021/jo01142A015
专利号:US-11858953-B2 优先权日:2018-04-04 标 题:Compositions and methods for synthesis of phosphorylated molecules 发明人:CHAPUT JOHN; LIAO JEN-YU; BALA SAIKAT 权利人:UNIV CALIFORNIA 摘要:The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.
专利号:US-11401235-B2 优先权日:2015-09-22 标 题 :Synthesis of terphenyl compounds 发明人:KAYE ANTHONY; QUAZI NURUL; FEAST GEORGE; LAKSHMAN MARSHNIL 权利人:VECTUS BIOSYSTEMS LTD 摘要:The present invention relates novel methods of synthesizing terphenyl compounds and in particular to novel methods for the synthesis of a compound of Formula I n nor intermediates thereof.
专利号:US-8987493-B2 优先权日:2010-05-20 标题 :Process for synthesis of silane dipeptide analogs 发明人:SIEBURTH SCOTT MCNEILL; BO YINGJIAN 权利人:SIEBURTH SCOTT MCNEILL; BO YINGJIAN; Temple University—Of the Commonwealth System of Higher Education 摘要:The invention provides a method of preparing silane dipeptide analogs, comprising the steps of treating a solution of a substituted 1,2-oxasilolane with lithium metal to form a solution of the dilithium salt of a substituted 3-hydroxypropylsilanol, and reacting the solution of the dilithium salt of the substituted 3-hydroxypropylsilanol with a substituted enamine.
专利号:US-10745354-B2 优先权日:2017-11-01 标题 :Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols 发明人:STOLTZ BRIAN M; NGAMNITHIPORN AURAPAT; JETTE CARINA I; BACHMAN SHOSHANA; VIRGIL SCOTT C; LACKNER SEBASTIAN 权利人:CALIFORNIA INST OF TECHN 摘要:The present disclosure provides methods for enantioselective synthesis of cyclic and acyclic α-quaternary carboxylic acid derivatives via nickel-catalyzed allylic alkylation.
专利号:US-2004044225-A1 优先权日:2001-06-01 标 题:Chiral and achiral synthesis of 2-acyl substituted chromanes and their derivatives 发明人:KANTER JAMES; MARLOWE CHARLES; PANDEY ANJALI; MULLINS JOHN J G; SCARBOROUGH ROBERT; BUTKE GREG; JACOBSON BARRY; WALKER DEREK 摘要:Disclosed are processes for producing a (2S) or (2R) 4-oxo-chroman-2-yl acyl compounds and chroman-2-yl acyl compounds, esters or amides thereof as well as derivatives thereof. Such processes may involve chiral synthesis or achiral synthesis, preferably coupled with a resolution procedure. Such compounds, particularly (2S) or (2R) acetic acid esters, are useful intermedates for producing platelet aggregation inhibitors and/or are themselves potent platelet aggregation inhibitors. Further disclosed are processes for making derivatives of such substantially pure, or enhanced compositions of single (2R) or (2S) enantiomer intermediates or processes for producing final products or salts from such desired enantiomers.
专利号:US-9981935-B2 优先权日:2013-07-05 标 题:Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of acids 发明人:MEDLOCK JONATHAN ALAN; LETINOIS ULLA; NETSCHER THOMAS; BONRATH WERNER 权利人:DSM IP ASSETS BV 摘要:The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of a specific type and of at least one Bransted acid or in the presence a specific chiral compound having a Bransted acid functional group in the molecule.
1: Xie CC, Zhang BP, Wang HN, Li WY, Cai ZL, He Y, Ji K, Chen JJ. Flavoring agent dihydrocoumarin alleviates IgE-mediated mast cell activation and allergic inflammation. Food Funct. 2022 Mar 21;13(6):3621-3631. doi: 10.1039/d2fo00190j. 18(12):2655. doi: 10.3390/ijms18122655. 3: Yang H, Zhou S, Wu L, Wang L. Interference of Dihydrocoumarin with Hormone Transduction and Phenylpropanoid Biosynthesis Inhibits Barnyardgrass (Echinochloa crus-galli) Root Growth. Plants (Basel). 2022 Sep 26;11(19):2505. doi: 10.3390/plants11192505. 4: Hou HM, Jiang F, Zhang GL, Wang JY, Zhu YH, Liu XY. Inhibition of Hafnia alvei H4 Biofilm Formation by the Food Additive Dihydrocoumarin. J Food Prot. 2017 May 1;80(5):842-847. doi: 10.4315/0362-028X.JFP-16-460. 156 Suppl
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