CAS: 19472-74-3; 2-Bromobenzyl Cyanide

上下游产品

CAS号3433-80-5 邻溴溴苄 | CAS号4001-73-4 2-溴苯甲酰胺 | CAS号850335-71-6 2-bromo-1-[(eth... | CAS号10442-39-4 氰化四丁基胺 | CAS号94236-21-2 1-溴-2-((甲氧基甲氧基)甲基)苯 | CAS号151-50-8 氰化钾 | CAS号860190-08-5 3-(2-bromo-phen... | CAS号95-46-5 2-溴甲苯 | CAS号506-77-4 氯化氰 | CAS号1074-15-3 1-溴-2-(2-溴乙基)苯 | CAS号494-19-9 亚氨基二苄 | CAS号311-28-4 四丁基碘化铵 | CAS号325141-71-7 2-氰基甲基苯基硼酸频哪醇酯 | CAS号140-29-4 苯乙腈 | CAS号90841-47-7 2-溴苯丁酸 | CAS号28049-62-9 1-(2-溴苯基)-环丁烷甲腈 | CAS号304876-29-7 2',3',5',6'-四氢螺... | CAS号2510-55-6 9-氰基菲

苯乙腈置于n-溴代丁二酰亚胺(Nbs),Palladium Diacetate,Copper(II) Bis(Trifluoromethanesulfonate)体系中,用 1,2-二氯乙烷 用作溶剂,以71%的收率获得邻溴氰苄
参考文献:钯催化,苄基腈,芳基温瑞布酰胺和苯胺的邻位选择性c-h卤化反应
标题:钯催化,苄基腈,芳基温瑞布酰胺和苯胺的邻位选择性c-h卤化反应
摘要:本文报道了钯催化的邻位选择性c-h卤化方法.这项工作的重点是在存在活化的c(sp 3)-H键的情况下对苄腈进行高选择性的c(sp 2)-H官能化,这将导致卤代产物的非常好收率和极好的区域选择性.与苄基腈一起,已经评估了使用非质子条件转化的芳基weinreb酰胺和苯胺化物的转化率.机理研究在反应途径和指导小组能力方面产生了有趣的方面.
Doi:10.1021/acs.Joc.6B02731

专利信息

专利号:US-7285686-B2
优先权日:2002-11-25
标 题:Process for the preparation of 1,3-substituted indenes
发明人：HANDFIELD JR ROBERT EUGENE; WATSON TIMOTHY J N; JOHNSON PHILLIP JAMES; ROSE PETER ROBERT
权利人:PFIZER
摘要:An improved process for the preparation of 1,3 substituted indenes which are useful intermediates in the synthesis of aryl fused azapolycyclic compounds as agents for the treatment of neurological and psychological disorders.

专利号:WO-2021074309-A1
优先权日:2019-10-16
标 题:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives as fungicides for combating specific phytopathogens
发明人：WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; SEN INDIRA; BIERI STEPHANE; DIGGELMANN MARTIN
权利人:SYNGENTA CROP PROTECTION AG
摘要:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-3,4-dihydroisoquinoline derivative of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale) when spayed on plants), as well as comparative data against three prior art compounds (e.g. pages 52 to 85; formulation examples; examples A1 to A3; table E; compounds E.01 to E.187; biological examples). Exemplary compounds are e.g.: 5-bromo-1-(8-fluoro-3-quinolyl)spiro[4H-isoquinoline-3,1'- cyclopropane] (example A1) 5-bromo-1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline (example A2) 1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline-5-carbonitrile (example A3)

专利号:CN-105568312-B
优先权日:2016-01-06
标题:A kind of method of indirect electrocatalytic synthesis of 2-arylpyrrole compound

专利号:US-2008177110-A1
优先权日:2006-07-26
标题 :Processes for the synthesis of O-desmethylvenlafaxine

专利号:WO-2008013994-A2
优先权日:2006-07-26
标题:Processes for the synthesis of o-desmethylvenlafaxine

专利号:EP-1917237-A2
优先权日:2006-07-26
标 题:Processes for the synthesis of o-desmethylvenlafaxine