CAS: 6381-59-5; Potassium Sodium (2R,3R)-2,3-Dihydroxysuccinate Tetrahydrate

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CAS号87-69-4 酒石酸 | CAS号868-14-4 酒石酸氢钾 | CAS号6106-24-7 L-酒石酸二钠二水合物 | CAS号526-94-3 酒石酸氢钠 | CAS号4958-46-7 potassium racem...

专利信息

专利号:US-8796454-B2
优先权日:2012-05-04
标 题 :Synthesis of [2.2.2]-diazabicyclic ring systems
发明人：SCHEERER JONATHAN R
权利人:COLLEGE WILLIAM & MARY
摘要:Herein we describe compositions and methods for the synthesis of [2.2.2]-diazabicyclic structures comprising a domino reaction sequence involving aldol condensation, alkene isomerization, and intramolecular hetero-Diels-Alder cycloaddition. Excellent diastereofacial control during the cycloaddition is enforced with a removable chiral phenyl aminal diketopiperazine substituent. The reaction sequence rapidly generates molecular complexity and is competent with both enolizable and non-enolizable aldehyde substrates. This method provides an efficient route to [2.2.2]-diazabicyclic structures, common to bioactive prenylated indole alkaloids such as the brevianamides and stephacidins.

专利号:US-7884128-B2
优先权日:2005-10-13
标题:Process for total synthesis of pladienolide B and pladienolide D
发明人：KANADA REGINA MIKIE; ITO DAISUKE; SAKAI TAKASHI; ASAI NAOKI; KOTAKE YOSHIHIKO; NIIJIMA JUN
权利人:EISAI R&D MAN CO LTD
摘要:Process for producing compound of Formula: n nwherein P 2 , P 3 and R 2 are the same as defined below, characterized by comprising reacting a compound represented by Formula (7):n n nwherein P 3 means a protecting group for hydroxy group; and Het means a 1-phenyl-1H-tetrazol-5-yl group, with a compound represented by Formula (8):n n nwherein P 2 means a protecting group for hydroxy group; and R 2 means a phenyl group which may be substituted, in the presence of a base.

专利号:US-11149024-B2
优先权日:2017-03-31
标 题 :Synthesis of Mcl-1 inhibitor
发明人：STEWART CRAIG ROBERT; HARDY SIMON; STARK ANDREW; HIRD ALEXANDER; YE QING; ZHENG XIAOLAN; FERRAR CATI; KOEK JAN; HAZRA DEBASIS
权利人:ASTRAZENECA AB
摘要:Disclosed are intermediates and methods of synthesizing Compound 1.

专利号:CN-108601760-A
优先权日:2016-02-12
标 题 :Intermediates in the synthesis of eribulin and related synthesis methods

专利号:US-2005020512-A1
优先权日:2002-10-02
标 题:Synthesis of oligomeric epicatechin and catechin-derived procyanidins

专利号:US-2004116718-A1
优先权日:2002-10-02
标题 :Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4beta,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest