CAS: 64963-01-5; 2-[[2-[[2-[2-[[2-Amino-3-(4-Hydroxyphenyl)Propanoyl]Amino]Propanoylamino]Acetyl]Amino]-3-Phenylpropanoyl]Amino]-4-Methylpentanoic Acid

上下游产品

2,4,5-didehydro-L-Leu5>Leu-enkephalin2,4,5-didehydro-L-Leu5Leu-enkephalin α-(tert-butoxycarbonyl)-2,Leu5>enkephalinNα-(tert-butoxycarbonyl)-2,Leu5enkephalin N-benzyloxycarbonyl-O-benzyl-L-tyrosine {(R)-2-[(S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionylamino]-propionylamino}-acetic acid methyl ester

专利信息

专利号:US-11612556-B2
优先权日:2014-12-16
标 题:Peptidic compounds, compositions comprising them and uses of said compounds, in particular cosmetic uses
发明人：PESCHARD OLIVIER; DOUCET ANNE; LEROUX RICHARD; MONDON PHILIPPE
权利人:SEDERMA SA
摘要:The peptidic compound comprises at least an aminoacid which is lysine, ornithine, diaminopropionic acid or diaminobutyric acid or a derivative of these aminoacids, on which a carboxylic acid is grafted via a peptidic bound on the nitrogen of the lateral chain, said carboxylic acid comprising a (poly)cycle or (poly)heterocycle. Preferably, the grafted carboxylic acid is an aminoacid or a derivative, in particular selected from, a proline, a hydroxyproline or pyroglutamic acid.The peptidic compound can stimulate the synthesis of the main molecules constituting the extracellular matrix of the skin, especially collagen 1 and 4 and elastin. It can be used for topical cosmetic treatment such as a global anti-aging treatment, or for specific activities, including anti-wrinkles, moisturizing, to improve the mechanical properties of the skin, firmness/tone/elasticity/flexibility, to increase density and volume of the skin, improve skin radiance, for a restructuring effect and/or to fight stretch marks.

专利号:US-4629784-A
优先权日:1983-08-16
标 题:Synthesis of cyclopropane amino acids
发明人：STAMMER CHARLES H
权利人:UNIV GEORGIA RES FOUND
摘要:Cyclopropane ('Cyclopropyl') amino acids and peptides containing at least one cyclopropyl amino acid are disclosed. The processes for synthesizing cyclopropyl amino acids and peptides containing at least one cyclopropyl amino acid are also disclosed. Cyclopropyl amino acids are useful as enzyme inhibitors and as substitutes for natural amino acids in peptide hormones such as regulators of bodily functions to enhance bioactivity, to stabilize the peptide into which it is incorporated to cleavage by enzymes and to convert such peptides into enzyme inhibitors.

专利号:US-12161745-B2
优先权日:2019-03-28
标题:Peptides and compositions for use in cosmetics
发明人：GRAU-CAMPISTANY ARIADNA; PASTOR SILVIA; CARULLA PATRICIA; ESCUDERO JUAN CARLOS; BORAS JULIA A; KLEIN MARCO JAN
权利人:LIPOTRUE S L
摘要:A family of peptides which are able to increase synthesis of homeodomain protein Mohawk and useful as anti-aging agents and as rejuvenating agents.

专利号:US-10668000-B2
优先权日:2014-05-22
标题:Peptides, compositions comprising them and uses in particular cosmetic uses
发明人：PESCHARD OLIVIER; DOUCET ANNE; LEROUX RICHARD; MONDON PHILIPPE
权利人:SEDERMA SA
摘要:The peptides have the general following formula: X-Pro*-Pro*-Xaa-Y in which: •Xaa is selected from Leucine (Leu, L), Arginine (Arg, R), Lysine (Lys, K), Alanine (Ala, A), Serine (Ser, S), and Aspartic acid (Asp, D); •At the N terminal end of the peptide, X is selected from H, —CO—R1 and —SO 2 —R 1 ; •At the C terminal end of the peptide, Y is selected from OH, OR 1 , NH 2 , NHR 1 and NR 1 R 2 ; •R 1 and R 2 are, independently from each other, selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy and aryloxy group, that can be linear, branched, cyclic, poly-cyclic, non-saturated, hydroxylated, carbonylated, phosphorylated and/or sulfured, and which skeletum can comprise an heteroatom, in particular an O, S and/or N atom; •Pro* correspond to a Proline, an analogue or derivative thereof; •if X is H then Y is selected from OR 1 , NH 2 , NHR 1 and NR 1 R 2 , and if Y is OH then X is —CO— or —SO 2 —R 1 ; and the peptide hypoxanthine-Pro-Pro-Arg being excluded. The invention provides the use of the peptides of above formula I to stimulate the synthesis of the molecules constituting the dermal extracellular matrix, including collagen I and IV and elastin. A cosmetic treatment according to the invention includes anti-aging, anti-wrinkles, improving mechanical properties of the skin, firmness/tone/elasticity/suppleness/flexibility, increasing density and volume of the skin, restructuring effect, fighting stretch marks, improving skin barrier and/or skin hydration.

专利号:BR-112016022455-B1
优先权日:2014-03-31
标 题 :use of a supernatant from cultures of a strain of bacillus pumilus species, unnatural cosmetic or dermopharmaceutical composition; skin, stimulate collagen synthesis and / or hyaluronic acid synthesis, treatment of skin tightening and / or prevention of loss of skin firmness

专利号:US-2015183823-A1
优先权日:2009-04-17
标题:Cosmetic or pharmaceutical compositions including tripeptides capable of stimulating cyclic adenosine monophosphate synthesis and their use in the treatment and/or care of the skin and/or hair