CAS: 1077-94-7; 5-Bromo-1H-Indazole-3-Carboxylic Acid

相似化合物

201227-38-5 78155-74-5 201227-39-6

上下游产品

吲唑-3-羧酸 1H-Indazole-3-Carboxylic Acid 4498-67-3

Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于铬,溶剂黄146体系中,化学反应生成5-溴吲唑-3-甲酸
参考文献:Fischer,E.; Tafel,Justus Liebigs Annalen Der Chemie,1885,Vol. 227,P. 305,316
标题:Fischer,E.; Tafel,Justus Liebigs Annalen Der Chemie,1885,Vol. 227,P. 305,316

专利信息

专利号:WO-2011050245-A1
优先权日:2009-10-23
标 题:Bicyclic heteroaryls as kinase inhibitors
发明人：FENG YANGBO; CHEN YEN TING; SESSIONS HAMPTON; MISHRA JITENDRA K; CHOWDHURY SARWAT; YIN YAN; LOGRASSO PHILIP; LUO JUN-LI; BANNISTER THOMAS; SCHROETER THOMAS
权利人:FENG YANGBO; CHEN YEN TING; SESSIONS HAMPTON; MISHRA JITENDRA K; CHOWDHURY SARWAT; YIN YAN; LOGRASSO PHILIP; LUO JUN-LI; BANNISTER THOMAS; SCHROETER THOMAS
摘要:The invention is directed to heteroaryl compounds useful as inhibitors of various kinase enzymes. In various embodiments, the invention provides a heteroaryl compound having inhibitory bioactivity with respect to a Rho kinase, an AKT kinase, a p70S6K kinase, a LIM kinase, an IKK kinase, a Flt kinase, an Aurora kinase, or a Src kinase, or any combination thereof. Compounds of the invention include bicyclic heteroaryl compounds of formula (I), which can contain a bridging nitrogen atom at a ring junction. The invention further provides methods of synthesis of compounds of the invention, pharmaceutical compositions, pharmaceutical combinations, and methods of treatment of malconditions using compounds of the invention.