CAS: 21770-81-0; 1-Methylguanidine Hydrochloride

上下游产品

methylamine hydr°Chloride N-Cyanoguanidine 5-Ethoxy-2-methylamino-1H-pyrimidine-4,6-dione 2-amino-1-methyl-5,6-dihydro-1H-pyrimidin-4-one 1-(3-Ethoxypropionyl)-3-methyl-guanidin 2-methylamino-1H-imidazole-4,5-dione

专利信息

专利号:US-9085538-B2
优先权日:2010-07-26
标题:Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof
发明人：CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO
权利人:CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO; LEK PHARMACEUTICALS
摘要:The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.

专利号:WO-2014080341-A1
优先权日:2012-11-21
标题 :New process for the synthesis of trichloropyrimidine-amine derivatives
发明人：Czibula László; Dobay László; SZAVICSKÓ KRISZTINA; KISS-BARTOS DOROTTYA; Nagyné Bagdy Judit
权利人:RICHTER GEDEON NYRT
摘要:The invention relates to a new process for the synthesis of 2-(N-methyl)-amino-4,5,6- trichloro-l,3-pyrimidine, which is more economical than the known process, as well as the new compounds synthesized as intermediates in the process: 2-(N',N'-dimethylamino- methylene)-amino-4,5,6-trichloro-l,3-pyrimidine and 2-(N-formyl)-amino-4,5,6-trichloro-l,3- pyrimidine.

专利号:US-2014051854-A1
优先权日:2010-07-26
标题 :Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof

专利号:WO-2012013325-A1
优先权日:2010-07-26
标题 :Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof

专利号:EP-2598484-A1
优先权日:2010-07-26
标 题:Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof

专利号:EP-2922824-A1
优先权日:2012-11-21
标题 :New process for the synthesis of trichloropyrimidine-amine derivatives