专利号:US-2022219156-A1 优先权日:2019-04-29 标题:Catalyst for the catalytic synthesis of urea 发明人:GLOTZBACH CHRISTOPH; TENHUMBERG NILS; EL HAWARY TAREK; MAKHYNYA YEVGENY; LEITNER WALTER; KLANKERMAYER JÜRGEN; SCHUMACHER HANNAH 权利人:THYSSENKRUPP IND SOLUTIONS AG; THYSSENKRUPP AG 摘要:A ruthenium-phosphine complex can be used as a catalyst in a method for the catalytic synthesis of urea. The method may comprise more particularly a reaction of formamide or of formamide with ammonia in the presence of the catalyst to form urea and hydrogen. Through the use of the ruthenium-phosphine complex as the catalyst, catalytic preparation of urea from formamide or from formamide with ammonia is provided for the first time. This allows for synthesis under mild conditions and virtually no formation of byproducts. Further, using an acid as a cocatalyst in the catalytic synthesis or the reaction can lead to an improvement in urea yield.
专利号:US-2024368099-A1 优先权日:2022-01-18 标 题:Methods for the synthesis of di(hydroxymethyl)tetrahydrofuran and its application in polyesters and polyurethanes 发明人:SPIEGELBERG BRIAN; BRANDT ADRIAN; BECK HORST; KUX ALEXANDER; TIN SERGEY; DE VRIES JOHANNES GERARDUS 权利人:HENKEL AG & CO KGAA 摘要:The present invention relates to the synthesis of di(hydroxymethyl)tetrahydrofuran (DHMTHF) and the preparation of trans-enriched mixtures of DHMTHF. The invention further refers to polyester polyols which are obtained by reaction of cis/trans DHMTHF mixtures with a dicarboxylic acid. The invention further relates to polyurethanes and compositions containing a polyester polyol comprising DHMTHF, in particular to such polyurethane-containing (adhesive) compositions.
专利号:US-11407993-B2 优先权日:2017-02-14 标 题 :Method for the synthesis of DNA conjugates by micellar catalysis 发明人:BHAT AVINASH SHASHIDHAR; KLIKA SKOPIC MATEJA; BRUNSCHWEIGER ANDREAS; WEBERSKIRCH RALF 权利人:UNIV DORTMUND TECH 摘要:A method for the synthesis of a chimeric conjugate molecule by micellar catalysis that may form part of DNA-encoded compound libraries. A DNA-coupled organic starter molecule may be reacted with another organic compound, using a catalyst located within a micelle, to form a conjugate of an organic candidate compound coupled to a DNA identifier tag.
专利号:US-4891442-A 优先权日:1987-03-09 标 题 :Process for synthesis of β-phenylalanine 发明人:LIN JIANG-JEN; KNIFTON JOHN F 权利人:TEXACO INC 摘要:N-acetyl-β-phenylalanine is synthesized by reacting phenylacetaldehyde, acetamide and synthesis gas with a catalyst comprising a cobalt-containing compound in conjunction with a cocatalyst that may be either a Group VB or VIB containing ligand, or a rhodium compound optionally bonded to one or more Group VB or VIB donor ligands, at a temperature of at least 50° C. and a pressure of at least 500 psi.
专利号:WO-2019020508-A1 优先权日:2017-07-26 标 题 :PROCESS FOR THE PREPARATION OF HIGH-PURITY RUCAPARIB 发明人:BELOGI GIANLUCA; MAZZONI ANDREA; SERRA STEFANO; NOVO BARBARA 权利人:OLON SPA 摘要:The present invention relates to a new low environmental impact method for the synthesis of rucaparib with high yield and purity, said process comprising a regioselective coupling reaction between indole and iodo-aryl, carried out in water in the presence of a catalyst. The process of the invention is industrially advantageous because in the key coupling step, high regioselectivity is achieved without the use of complex intermediates or potentially toxic and environmentally harmful solvents.
专利号:US-8877977-B2 优先权日:2011-11-25 标题 :Synthesis of polyalkylenepolyamines having a low color index by homogeneously catalyzed alcohol amination in the presence of hydrogen 发明人:STRAUTMANN JULIA; SCHAUB THOMAS; HUEFFER STEPHAN; MAAS STEFFEN; PACIELLO ROCCO 权利人:STRAUTMANN JULIA; SCHAUB THOMAS; HUEFFER STEPHAN; MAAS STEFFEN; PACIELLO ROCCO; BASF SE 摘要:Process for the preparation of polyalkylenepolyamines by homogeneously catalyzed alcohol amination, in which aliphatic amino alcohols are reacted with one another or aliphatic diamines or polyamines are reacted with aliphatic diols or polyols with the elimination of water in the presence of a homogeneous catalyst and in the presence of hydrogen gas. Polyalkylenepolyamines obtainable by such processes and polyalkylenepolyamines comprising hydroxy groups, secondary amines or tertiary amines. Uses of such polyalkylenepolyamines as adhesion promoters for printing inks, adhesion promoters in composite films, cohesion promoters for adhesives, crosslinkers/curing agents for resins, primers for paints, wet-adhesion promoters for emulsion paints, complexing agents and flocculating agents, penetration assistants in wood preservation, corrosion inhibitors, immobilizing agents for proteins and enzymes.
参考标题:Homogeneous Catalytic Hydrogenation Of Amides To Amines 作者:Jacorien Coetzee,Deborah L. Dodds,Jürgen Klankermayer,Sandra Brosinski,Walter Leitner,Alexandra M. Z. Slawin,David J. Cole-Hamilton |发布日期:2013.8.12 摘要:Hydrogenation Of Amides In The Presence Of [ru(Acac)3] (Acach=2,4‐pentanedione), Triphos [1,1,1‐tris‐ (Diphenylphosphinomethyl)Ethane] And Methanesulfonic Acid (Msa) Produces Secondary And Tertiary Amines With Selectivities As High As 93 % Provided That There Is At Least One Aromatic Ring On N. The System Is Also Active For The Synthesis Of Primary Amines. In An Attempt To Probe The Role Of Msa And
合成参考文献
摘要:Stanforth, S. P., Science of Synthesis Knowledge Updates, (2014) 3, 5. 摘要:Demchuk, O. M.; Stankevič, M.; Pietrusiewicz, K. M., Science of Synthesis Knowledge Updates, (2015) 1, 364. 摘要:Nahra, F.; Cazin, C. S. J., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 310. 摘要:Shi, Y.; Cole-Hamilton, D. J.; Kamer, P. C. J., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 2, 204. 摘要:Shi, Y.; Cole-Hamilton, D. J.; Kamer, P. C. J., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 2, 239.