CAS: 23504-03-2; 4-Isopropylbenzene-1,3-Diol

上下游产品

2,4-dimethoxy-1-(prop-1-en-2-yl)benzene isopropyl alcohol recorcinol 2',4'-dimethoxyacetophenone 1-(2,4-Dihydroxy-5-isopropyl-phenyl)-2,2,2-trifluoro-ethanone 4-bromo-6-isopropyl-benzene-1,3-diol 1-{3-[2,6-Dihydroxy-3-isopropyl-5-(2,2,2-trifluoro-acetyl)-benzyl]-2,4-dihydroxy-5-isopropyl-phenyl}-2,2,2-trifluoro-ethanone 1-(2,4-dihydroxy-5-isopropylphenyl)ethan-1-one

2-(2,4-Dimethoxyphenyl)Propan-2-Ol置于三乙基硅烷,三溴化硼体系中,用 二氯甲烷,三氟乙酸 用作溶剂,化学反应 3.0H,反应生成4-异丙基苯-1,3-二醇
参考文献:在环境条件下由有机碱介导的kolbe-schmitt型反应†
标题:在环境条件下由有机碱介导的kolbe-schmitt型反应†
摘要:间苯二酚有机碱的组合使用在环境条件下实现了kolbe-Schmitt型反应.当将间苯二酚(3-羟基苯酚衍生物)在二氧化碳气氛下用dbu处理时,亲核加成反应继续进行,从而以高收率得到了相应的水杨酸衍生物.
Doi:10.1039/c9Cc04550C

专利信息

专利号:US-2008125587-A1
优先权日:2006-05-25
标 题 :Synthesis of triazole compounds that modulate HSP90 activity
发明人：CHIMMANAMADA DINESH U; LEE CHI-WAN; JAMES DAVID; ZHANG SHIJIE; YING WEIWEN; CHAE JUNGHYUN; PRZEWLOKA TERESA
权利人:CHIMMANAMADA DINESH U; LEE CHI-WAN; JAMES DAVID; ZHANG SHIJIE; YING WEIWEN; CHAE JUNGHYUN; PRZEWLOKA TERESA
摘要:The present invention provides novel methods of preparing triazole compounds which inhibit the activity of Hsp90. One embodiment of the invention is directed to methods for preparing a triazole compound represented by the following Structural Formula: n n n n n n n n n n or a tautomer, a pharmaceutically acceptable salt, solvate, or clathrate, or a prodrug thereof, comprising the steps of: a) reacting an amide represented by the following Structural Formula: n n n n n n n n n n with a thionation reagent to form a thioamide; b) reacting the thioamide of step a) with hydrazine to form a hydrazonamide; c) reacting the hydrazonamide of step b) with a carbonylation or a thiocarbonylation reagent. n In one embodiment, the present invention is a method of synthesis of a compound of formula (IA) n n n n n n n n n n or a tautomer, a pharmaceutically acceptable salt, solvate, or clathrate, or a prodrug thereof, comprising reacting a compound of formula (IIA) n n n n n n n n n n with an oxidizing agent, thereby producing a compound of formula (IA). n The present invention is also directed to a method of preparing a compound or a tautomer thereof represented by the following Structural Formula: n n n n n n n n n n or a tautomer, a pharmaceutically acceptable salt, solvate, or clathrate, or a prodrug thereof. The method comprises the step of reacting a first starting compound represented by the following Structural Formula: n n n n n n n n n n in the presence of a mercuric salt, with a second starting compound represented by the following Structural Formula:

专利号:WO-2025181827-A2
优先权日:2024-02-26
标 题:Process development for substituted resorcinol production from cyclohexane-1,3-diones
发明人：DAS PRALAY; YAMINI; MEHRA PUSHKAR; KUMAR ASHISH; BAINS ROHIT; KUMAR AJAY; RAM SHANKAR; SHARMA DHARMINDER; CHAUHAN ARVIND SINGH
权利人:COUNCIL SCIENT IND RES
摘要:The invention provides a scalable and low cost process for synthesis of different high value 4-alkyl resorcinols such as 3-(2,4-dihydroxyphenyl)propanoic acid, 3-(2,4- dihydroxy-5-methylphenyl)-2-methylpropanoic acid, 4-methyl resorcinol, 4-isopropyl resorcinol and 4-hexyl resorcinol from their corresponding cyclohexane-1,3-diones. The present invention also provides a process for preparing cyclohexane-1,3-diones which is the starting materials for the synthesis of resorcinols.

专利号:WO-2009075890-A2
优先权日:2007-12-12
标题 :Method for synthesis of triazole compounds that modulate hsp90 activity

专利号:WO-2016009359-A1
优先权日:2014-07-15
标 题:Synthesis of 2,2-bis(3-phenyl-4-hydroxyphenyl) propane (php)

专利号:US-10793848-B2
优先权日:2014-01-31
标题 :Immobilized proteins and use thereof
发明人：CASSIMJEE KARIM ENGELMARK; BÄCKVALL JAN-ERLING
权利人:ENGINZYME AB
摘要:The invention relates to an immobilized protein material comprising a protein that is immobilized on a glass material or organic polymer through affinity tag binding. The glass material may be a porous glass material such as (hybrid) controlled porosity glass. The invention also relates to the use of an immobilized enzyme material as a heterogeneous biocatalyst in chemical synthesis. The invention further relates to a method for the immobilization of affinity tagged proteins on a glass material or organic polymer, and to a method for the purification and isolation of affinity tagged proteins by the immobilization of such proteins on a glass material or organic polymer.

专利号:CN-107556164-B
优先权日:2017-09-15
标 题:Synthesis method of 4-isopropylresorcinol