3,3-二甲基环己酮置于硝酸体系中,化学反应生成 3,3-二甲基戊二酸 参考文献:Sur La Double énolisation De La Diméthyl-3,3 Cyclohexanone 标题:Sur La Double énolisation De La Diméthyl-3,3 Cyclohexanone 摘要:不可用 DOI:10.1139/v64-039
专利号:US-4341706-A 优先权日:1980-10-10 标题 :Process for the preparation of carbapenem antibiotics 发明人:CHRISTENSEN BURTON G; SHIH DAVID H 权利人:MERCK & CO INC 摘要:Disclosed is a process for the synthesis of carbapenem antibiotics I and their pharmaceutically acceptable salts and esters from 1: wherein: R7, R6, R1, R2 and R8 are selected from hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, spirocycloalkyl, cycloalkylalkyl, alkylcycloalkyl, aryl, aralkyl, aralkenyl, aralkynyl, heteroalkyl, heteroaralkyl, heterocyclyl and heterocyclyalkyl.
专利号:US-10202488-B2 优先权日:2015-02-05 标 题:Isocyanate-free synthesis of carbonate-modified polymers 发明人:CRON CHRISTINA; BRENNER GABRIELE 权利人:EVONIK DEGUSSA GMBH 摘要:The present invention relates to an isocyanate-free and preferably solvent-free process for preparing polymers containing five-membered cyclic carbonate groups. In particular, the present invention is directed to a process for preparing polymers bearing cyclic carbonate groups by reacting carboxyl-bearing polymers selected from the group including polyesters based on di- or polyols and di- or polycarboxylic acids or derivatives thereof or poly(meth)acrylates, with hydroxyl-functionalized five-membered cyclic carbonates, without addition of isocyanates.
专利号:WO-2025124564-A1 优先权日:2023-12-15 标题:Polyester synthesis based on aspartic acid modification 发明人:ZHANG KECHUN; CHEN XI; LEI TENGFEI; LIU SHENGYANG 权利人:MINT BIOTECHNOLOGIES CO LTD 摘要:Provided in the present invention is polyester synthesis based on aspartic acid modification. A monomer of a unique structure of an imide ring is obtained based on aspartic acid and a dibasic acid likely to be cyclized, the monomer is based on the aspartic acid, can be derived from biomass, is low in cost and renewable, meets the requirement of sustainable development, and the unique structure of the monomer can regulate and control various properties of polyester materials, such as the mechanics, temperature resistance, hydrophilicity and hydrophobicity, and crystallization.
专利号:WO-2012163563-A1 优先权日:2011-05-31 标题:New strontium salts, synthesis and use thereof in the treatment of osteoporosis 发明人:MOURELLE MANCINI MARISABEL; DEL CASTILLO NIETO JUAN CARLOS 权利人:LACER SA; MOURELLE MANCINI MARISABEL; DEL CASTILLO NIETO JUAN CARLOS 摘要:The present invention relates to a strontium salt (I) wherein n is an integer which can take the values of 0 or 1 m is an integer which can take the values of 0 or 1 R is hydrogen or methyl and stereoisomers or hydrates thereof, to methods for its synthesis, and use in the treatment and/or prophylaxis of a cartilage and/or bone disease and/or conditions resulting in a dysregulation of cartilage and/or bone metabolism in a mammal.
专利号:US-2022010060-A1 优先权日:2018-12-12 标题:Polycarbonate polyols 发明人:FENG XIAOSHUANG; PATIL NAGANATH; BOOPATHI Senthil; GNANOU YVES; HADJICHRISTIDIS NIKOS 权利人:UNIV KING ABDULLAH SCI & TECH 摘要:Embodiments of the present disclosure describe polymerization systems for the synthesis of polycarbonate polyols, methods of synthesizing polycarbonate polyols using the polymerization systems, methods of recovering initiators and/or activators for use or re-use in the synthesis of polycarbonate polyol, and the like. The polymerization systems can comprise an initiator including a mono- or multi-functional carboxylate or carbonate salt having an organic cation as a counter-ion; an optional co-initiator including a mono- or multi-functional protic compound selected from acids, alcohols, water, and combinations thereof; and an activator including a borane compound selected from alkyl boranes and aryl boranes; wherein the activator and one or more of the initiator and co-initiator associate to form an ate complex.
专利号:EP-0030031-B1 优先权日:1979-12-03 标 题 :6-(1-hydroxyethyl)-2-(2-aminoethylthio)-1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acids, a process for preparing the same, an antibiotic pharmaceutical composition comprising the same, intermediates useful in a synthesis of that kind and processes for preparing intermediates suitable for the synthesis of that kind
摘要:T. C. Bruice and W. C. Bradbury, J. Am. Chem. Soc. 87, 4851 (1965). 摘要:R. H. Jones and D. I. Stock, J. Chem. Soc. 1960, 1092. 参考文献:10.1023/b:boli.0000037343.90450.8d 摘要:Napolitano N, Wiley V, Pitt JJ. Pseudo-glutarylcarnitinaemia in medium-chain acyl-CoA dehydrogenase deficiency detected by tandem mass spectrometry newborn screening. J Inherit Metab Dis. 2004;27(4):465–71. doi: 10.1023/b:boli.0000037343.90450.8d.