CAS: 98-91-9; Benzothioic S-Acid

上下游产品

CAS号98-88-4 苯甲酰氯 | CAS号65-85-0 苯甲酸 | CAS号644-32-6 二硫化二苯甲酰 | CAS号618-32-6 苄氧基溴 | CAS号62-55-5 硫代乙酰胺 | CAS号93-97-0 苯甲酸酐 | CAS号1850-15-3 硫化苯甲酰 | CAS号1356496-19-9 thiobenzoic aci... | CAS号936-61-8 Thiobenzoic aci... | CAS号150-60-7 二苄基二硫 | CAS号52772-11-9 硫化水杨酸乙醋 | CAS号3393-96-2 4'-硝基苯甲酰苯胺 | CAS号39251-01-9 Benzenecarbothi... | CAS号55-21-0 苯甲酰胺 | CAS号455-32-3 苯甲酰氟 | CAS号2992-86-1 Pentafluorosulf... | CAS号94-50-8 苯甲酸辛酯 | CAS号939-52-6 4-氯-1-羰基-1-苯基丁烷 | CAS号139-66-2 苯硫醚 | CAS号1884-68-0 四苯基噻吩

苯甲酰氯置于lismgbr体系中,用 四氢呋喃,乙醚,环己烷 作为反应溶剂,化学反应 2.0H,以92%的收率获得产物硫代苯甲酸
参考文献:硫代甲酰胺与有机锂和格氏试剂的三组分偶联反应导致叔胺和硫醇化剂的形成
标题:硫代甲酰胺与有机锂和格氏试剂的三组分偶联反应导致叔胺和硫醇化剂的形成
摘要:开发了硫代甲酰胺与有机锂和格氏试剂之间的高效三组分偶联反应.已通过使用反应物和试剂的各种组合证明了该方法的通用性.关于反应机理的信息来自关键中间体的 1H 和 13C NMR 光谱检测.通过将有机锂试剂加入硫代甲酰胺而反应生成的中间体中的 Lis 基团用作离去基团.在这些反应中形成的固体副产物,配制成 [lismgbr],可用作硫醇化剂,将酰氯转化为硫代酸和硫代酸酐.
DOI:10.1021/ja068523F

专利信息

专利号:US-6013829-A
优先权日:1996-02-05
标 题 :Process for the asymmetric synthesis of S-acyl derivatives of 2-mercaptomethyl -3- phenyl propanoic acid, application to the synthesis of N-(mercaptoacyl) amino acid derivatives
发明人：DANVY DENIS; MONTEIL THIERRY; DUHAMEL PIERRE; DUHAMEL LUCETTE; LECOMTE JEANNE-MARIE; SCHWARTZ JEAN-CHARLES; NOEL-LEFEBVRE NADINE; GROS CLAUDE; PLAQUEVENT JEAN-CHRISTOPHE
权利人:BIOPROJET SOC CIV
摘要:PCT No. PCT/FR97/00218 Sec. 371 Date Nov. 26, 1997 Sec. 102(e) Date Nov. 26, 1997 PCT Filed Feb. 4, 1997 PCT Pub. No. WO97/29086 PCT Pub. Date Aug. 14, 1997Process for the asymmetric synthesis of S-acyl derivatives of 2-mercaptomethyl-3-phenylpropanoic acid of formula (I): characterized in that it comprises the steps consisting in: a) preparing the diol (VI) by reduction of a malonic ester (V) in the presence of a hydride; b) preparing the monoacetates (VII R) or (VII S) respectively; c) subjecting these monoacetates to an oxidation in order to form the acids (IX S) or (IX R); d) saponifying the compounds (IX S) or (IX R) in order to form the hydroxy acids (X S) or (X R); e) thioacylating the hydroxy acids (X S) or (X R) with a mercapto acid R1SH (XI), according to a Mitsunobu-type reaction, in order to lead to the desired acids (I R) (I S) respectively and application to the synthesis of N-(mercaptoacyl)amino acid derivatives (II).

专利号:US-2004058888-A1
优先权日:2000-01-13
标题:Methods for synthesis of alpha-d-gal (1~>3) gal-containing oligosaccharides
发明人：BORNAGHI LAURENT; DEKANY GYULA; DRINNAN NICHOLAS BARRY; PAPAGEORGIOU JOHN; WEST MICHAEL LEO
摘要:This invention relates to reagents and methods for synthesis of biologically active di- and tri-saccharides comprising α-D-Gal(1→3)-D-Gal. In particular the invention provides novel reagents, intermediates and processes for the solution or solid phase synthesis of α-D-galactopyranosyl-(1→3)-D-galactose, and derivatives thereof. In one preferred embodiments the invention provides a protected monosaccharide building block of general formula (II): in which R 3 is methoxy or methyl; R 1 is H, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4-chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl; and R 2 is H, Fmoc, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4 -chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl.

专利号:US-6184168-B1
优先权日:1997-09-22
标题:Synthesis of 1,4-trans-polybutadiene using a lanthanide organic acid salt catalyst
发明人：LYNCH THOMAS J
权利人:BRIDGESTONE CORP
摘要:The invention provides a catalyst composition, comprising: (a) an organolithium compound; and, (b) an organic acid salt of lanthanide series element; wherein: (1) only components (a) and (b) are required to promote the synthesis of 1,4-trans-polybutadiene; (2) the ratio of component (a) to component (b) is selected to maximize formation of the trans structure of said 1,4-trans-polybutadiene; and, (3) components (a) and (b) are selected for enabling further diblock synthesis. The invention further contemplates a process for using the catalyst to synthesize 1,4-trans-polybutadiene and other polymers and copolymers having trans configuration in the conjugated diene monomer contributed units.

专利号:US-7122693-B2
优先权日:1988-04-11
标题 :Acetaldehyde acetal compounds, their synthesis, and uses thereof
发明人：BELLEAU EXECUTRIX OF ESTATE PI; DIXIT DILIP M; NGUYEN-BA NGHE
权利人:SHIRE BIOCHEM INC
摘要:The acetaldehyde compounds, 2-thiobenzoylacetaldehyde diethylacetal, 2-benzoyloxyacetaldehyde bis(2-methoxyethyl)acetal, 2-hydroxyacetaldehyde bis( 2-methoxyethyl)acetal, 2-thiobenzoylacetaldehyde bis(2-methoxy-ethyl)acetal, and 2-thioacetaldehyde bis(2-methoxyethyl)acetal, are useful as intermediates in the synthesis of substituted 1,3-oxathiolanes and substituted 1,3-dioxolanes.

专利号:US-7935837-B2
优先权日:2008-04-30
标 题:Process for synthesis of androstane 17-β carbothioic acid and relative compounds thereof
发明人：HSU NAI-HSUAN; PANG CHU-YI; WU CHIEN-JEN; HUANG CHI-JEN; HSU CHIA-JUNG; LEE PEIMIN
权利人:CORUM INC
摘要:A process for synthesis of androstane 17-β carbothioic acid is provided. The process includes mixing an androstane 17-β carboxylic acid and a coupling reagent, and adding an alkanethioic acid to form an androstane 17-β carbothioic acid, wherein the androstane 17-β carbothioic acid has the formula (I): n n n n n n n n n n n n wherein R 1 represents hydrogen or haloalkyl groups, R 2 represents C 1-8 linear alkyl groups, C 1-8 branched alkyl groups, C 1-6 unsaturated acyclic groups or aromatic groups, R 3 represents hydrogen or hydroxyl, R 4 represents hydrogen, bromine, chlorine or fluorine and R 5 represents hydrogen, bromine, chlorine or fluorine. The process is a one-pot reaction.

专利号:US-4022672-A
优先权日:1976-04-02
标题:Electrochemical synthesis of insecticide intermediates
发明人：ALVAREZ MANUEL; FISHMAN MORRIS L
权利人:FMC CORP
摘要:1,1,1-Trihalo-4-methylpentenes, carrying 2-substituents selected from those conjugate bases of Bronsted acids which are leaving groups in beta eliminations, are reduced electrochemically to 1,1-dihalo-4-methylpentadienes, intermediates in the synthesis of pyrethroid insecticides.