CAS: 21149-17-7; Methyl 2-(((Benzyloxy)Carbonyl)Amino)Acrylate

相似化合物

55477-80-0 201338-62-7 1212-53-9

上下游产品

CAS号1676-81-9 N-苄氧羰基-L-丝氨酸甲酯 | CAS号14464-15-4 N-Cbz-DL-丝氨酸甲酯 | CAS号56618-03-2 Nα-(Carbobenzyl... | CAS号124-41-4 甲醇钠 | CAS号98632-91-8 N-苄氧羰基-D-丝氨酸(Β-内酯) | CAS号82611-65-2 N-CBZ-S-苯基-L-半胱氨酸 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号1010687-16-7 Z-L-Ser(O-B°C)-OMe | CAS号28819-05-8 Z-L-丙氨酸甲酯 | CAS号39692-63-2 Z-脱氢丙氨酸

N-苄氧羰酰基-L-丝氨酸甲酯置于三乙胺,Propynoic Acid Benzylamide体系中,用 氯仿 用作溶剂,化学反应 24.0H,反应生成苄基-脱氢-丙氨酸甲酯
参考文献:将氨基酸侧链共轭添加到炔烃和炔酸衍生物中
标题:将氨基酸侧链共轭添加到炔烃和炔酸衍生物中
摘要:使用适当保护的氨基酸来研究半胱氨酸的硫烷基的迈克尔加成,丝氨酸的羟基和赖氨酸的ε-氨基与共轭炔酮,炔属酸酯和炔属酰胺的加成反应.在每种情况下均形成预期的杂取代乙烯基产物.
Doi:10.1016/s0040-4020(97)10323-4

专利信息

专利号:US-12378196-B2
优先权日:2018-12-11
标 题 :Synthesis of (S)-6-hydroxytryptophan and derivatives thereof
发明人：SIMON WERNER; WERNER-SIMON SUSANNE; MüLLER CHRISTOPH
权利人:HEIDELBERG PHARMA RES GMBH
摘要:The present invention relates to novel methods and compounds for synthesizing amanitin derivatives. The invention in particular relates to methods for synthesizing (S)-6-hydroxy-tryptophan derivatives which can be used as building blocks for synthesizing amanitin derivatives or amatoxin drug conjugates. The invention further relates to intermediate compounds of said synthesis pathways for use in amanitin derivative and amatoxin drug conjugate synthesis, and to the use of particular catalysts suited for mediating said synthesis pathways.

专利号:US-8487108-B2
优先权日:2005-11-14
标题 :Piperidinyl carbamate intermediates for the synthesis of aspartic protease inhibitors
发明人：BALDWIN JOHN J; CLAREMON DAVID A; TICE COLIN; CACATIAN SALVACION; DILLARD LAWRENCE W; ISHCHENKO ALEXEY V; YUAN JING; XU ZHENRONG; MCGEEHAN GERARD; SIMPSON ROBERT D; SINGH SURESH B; ZHAO WEI; FLAHERTY PATRICK T
权利人:BALDWIN JOHN J; CLAREMON DAVID A; TICE COLIN; CACATIAN SALVACION; DILLARD LAWRENCE W; ISHCHENKO ALEXEY V; YUAN JING; XU ZHENRONG; MCGEEHAN GERARD; SIMPSON ROBERT D; SINGH SURESH B; ZHAO WEI; FLAHERTY PATRICK T; VITAE PHARMACEUTICALS INC
摘要:The present invention is directed to aspartic protease inhibitors. Certain aspartic protease inhibitors of the invention can be represented by the following structural formula or a pharmaceutically acceptable salt thereof. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.

专利号:CN-113166057-B
优先权日:2018-12-11
标题 :Synthesis of (S) -6-hydroxytryptophan and derivatives thereof

专利号:US-2025179018-A1
优先权日:2018-12-11
标 题:Synthesis of (s)-6-hydroxytryptophan and derivatives thereof

专利号:CN-113166057-A
优先权日:2018-12-11
标题:Synthesis of (S)-6-Hydroxytryptophan and its Derivatives

专利号:US-2022024870-A1
优先权日:2018-12-11
标 题:Synthesis of (S)-6-Hydroxytryptophan and Derivatives Thereof