CAS: 32673-41-9; 4-Imidazolemethanol Hydrochloride

相似化合物

822-55-9 33769-07-2 1072-84-0

上下游产品

CAS号50-00-0 甲醛 | CAS号6347-01-9 D-Fructopyranose | CAS号38585-61-4 4-(氯甲基)-1H-咪唑盐酸盐 | CAS号38993-84-9 (1-甲基-1H-咪唑-5-基)甲醇 | CAS号33769-07-2 (1-三苯甲基-1H-咪唑-4-基)甲醇 | CAS号226930-88-7 (1-异丁基-1H-咪唑-5-基)甲醇 | CAS号80304-50-3 1-苄基-5-羟甲基-1H-咪唑 | CAS号85102-84-7 (1-benzylimidaz... | CAS号3034-50-2 4-咪唑甲醛 | CAS号23785-22-0 4-氯甲基咪唑 | CAS号120277-50-1 4-(羟基甲基)-1H-咪唑-... | CAS号196298-99-4 [1-(2-氟-4-硝基苯基)...

4-(Fluoromethyl)-1-Trityl-1H-Imidazole置于盐酸体系中,用 溶剂黄146 作为反应溶剂,化学反应 1.0H,以99%的收率获得产物4-(Fluoromethyl)Imidazole Hydrochloride
参考文献:Preparation Of (Fluoromethyl)-And (Difluoromethyl)Imidazoles
标题:Preparation Of (Fluoromethyl)-And (Difluoromethyl)Imidazoles
摘要:2-(氟甲基)-和2-(二氟甲基)咪唑,以及4-(氟甲基)-和4-(二氟甲基)咪唑已通过对(羟甲基)咪唑或甲酰咪唑前体进行脱氧氟化制备.
DOI:10.1135/cccc20021335

专利信息

专利号:US-5521179-A
优先权日:1991-04-18
标题 :Heterocyclic amides
发明人：BERNSTEIN PETER R; SHAW ANDREW; THOMAS ROYSTON M; WARNER PETER; WOLANIN DONALD J
权利人:ZENECA LTD
摘要:The present invention relates to certain novel heterocyclic amides which are 1-pyridylacetamide compounds of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic amides, processes for preparing the heterocyclic amides, pharmaceutical compositions containing such heterocyclic amides and methods for their use.

专利号:US-5728695-A
优先权日:1994-12-23
标题 :Spiroketal derivatives, compositions containing them and their use as therapeutic agents
发明人：HARRISON TIMOTHY; OWEN SIMON NEIL; SEWARD EILEEN MARY; SWAIN CHRISTOPHER JOHN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to spiroketal derivatives of formula (I) and pharmaceutically acceptable salts thereof wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 9a , R 9b , m and n are as defined in the specification, and to processes for their preparation, to intermediates used in their synthesis, to pharmaceutical compositions containing them, and to their use in therapy. The compounds are of particular use in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia. ##STR1##

专利号:EP-0693287-A1
优先权日:1994-07-18
标 题:RNA cleaving or binding oligonucleotides
发明人：PEYMAN ANUSCHIRWAN DR; UHLMANN EUGEN DR
权利人:HOECHST AG
摘要:There are therapeutic agents for inhibiting protein synthesis containing two antisense oligonucleotides AO-1 and AO-2 with about 6-100 nucleotides, which bind to the target RNA at an adjacent site and at the 5 'end or 3' -Ends are linked via suitable spacers to conjugate molecules A and B, the conjugate molecules A and B each not being reactive per se, but brought into spatial proximity, forming a unit, and thus able to cleave the RNA catalytically or activated by the spatial proximity leads to the covalent binding of RNA.

专利号:CN-106632268-A
优先权日:2016-11-18
标 题 :Synthesis method of calmodulin inhibitor for treating brain-derived diseases