3-甲基噻吩置于磺酰氯体系中,化学反应生成2-氯-3-甲基噻吩 参考文献:Chlorination Of Thiophenes With Sulfuryl Chloride 标题:Chlorination Of Thiophenes With Sulfuryl Chloride 摘要: Doi:10.1021/ja01181A505
专利信息
专利号:US-4221915-A 优先权日:1977-03-11 标题:Process for preparing thiophene derivatives and thiophene derivatives obtained thereby 发明人:KONDO KIYOSHI; TSUNEMOTO DAIEI; FUJISAWA TAMOTSU 权利人:SAGAMI CHEM RES 摘要:Process for the preparation of a series of thiophene derivatives, from which 2-thiopheneacetic acid derivatives can easily be prepared, in high yields and selectivity by using substituted or unsubstituted thiophenes as the starting materials by easy operations. 2-Thiopheneacetic acid derivatives are very useful compounds as the chemical modifier of penicillin and cephalosporin. Novel compounds, i.e. α-arylthio-2-thiopheneacetic acids are also disclosed. These compounds are useful as the intermediates of the synthesis of 2-thiopheneacetic acids.
摘要:Ouali, A.; Taillefer, M., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 2, 103. 摘要:Harris, P. A., Science of Synthesis: Knowledge Updates, (2024) 1, 76.