CAS: 1460-57-7; Trans-Cyclohexane-1,2-Diol

该化合物是一个双环有机化合物,其特点是环氧环中相邻碳原子有两个氢氧(-OH)组,该化合物存在于一个环状环中,以跨式配置形式存在,这意味着氢氧基组位于环的对面,影响其物理和化学特性.Trans-1-2-Cyclohexanediol一般是无色的,不粘性液体或固体的,取决于温度,并且由于氢氧基组的极性,在水中可溶解.该化合物具有氢联结能力,可能影响其沸点和熔点.该化合物对各种化学应用感兴趣,包括作为有机合成和某些材料的可能的中间体,在确定其再活性和与其他物质的相互作用方面发挥着关键作用.应参考安全数据,以便处理和储存任何化学物质.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号110-83-8 环己烯 | CAS号1072-21-5 己二醛 | CAS号1759-71-3 顺式-1,2-环己二醇二乙酸酯 | CAS号286-20-4 环氧环己烷 | CAS号120-80-9 邻苯二酚 | CAS号6651-36-1 1-环己烯氧基三甲基硅烷 | CAS号122-60-1 环氧丙基苯基醚 | CAS号1792-81-0 顺式-1,2-环己二醇 | CAS号67-56-1 甲醇 | CAS号1072-21-5 己二醛 | CAS号765-87-7 1,2-环己二酮 | CAS号533-60-8 2-羟基环己酮 | CAS号124-04-9 己二酸 | CAS号928-81-4 6-Oxohexanoic acid | CAS号78002-77-4 2-hydroxy-6-hex... | CAS号108-94-1 环己酮 | CAS号872-53-7 环戊甲醛 | CAS号141-82-2 丙二酸 | CAS号110-15-6 琥珀酸; 丁二酸

合成工艺路线路线简述

  • 合成目标产物 Trans-1,2-Cyclohexanediol 主要起始原料 Cis-1,2-Cyclohexanediol
  • (文献来源)合成步骤主要原料 Cis-1,2-Cyclohexanediol

海关参考信息

专利信息


专利号:US-8642766-B2
优先权日:2008-05-05
标题 :Synthesis of (+) cortistatin A and related compounds
发明人:SHENVI RYAN A; GUERRERO CARLOS A; SHI JUN; LI CHUANG-CHUANG; BARAN PHIL S
权利人:SHENVI RYAN A; GUERRERO CARLOS A; SHI JUN; LI CHUANG-CHUANG; BARAN PHIL S
摘要:An in vitro synthesis of (+) cortistatin A from readily available precursors is disclosed, as are the syntheses of related 17-aryl substituted compounds, the 17-aryl substituted compounds themselves and novel compounds useful in their preparation.

专利号:US-4855425-A
优先权日:1986-08-27
标题:Process for the selective synthesis of ethylene diamines
发明人:MARSELLA JOHN A
权利人:AIR PROD & CHEM
摘要:The present invention is a process for the selective synthesis of alkanediamines by reacting a secondary amine with an alkanediol. High conversions and high selectivity for the production of alkanediamines is achieved by carrying out the reaction in the presence of a compound or complex of ruthenium in the absence of an organic phosphine co-catalyst.

专利号:WO-2014059961-A1
优先权日:2012-10-15
标 题 :Method for the synchronous absorption of carbon dioxide from flue gas and synthesis of dialkyl carbonates and alkylene carbonates
发明人:BÜTTNER HERMANN; Müller Jürgen; JONKER RAPHAEL; DOEDT SEBASTIAN; BOSSE TOBIAS; MAKRAN SEBASTIAN
权利人:BÜTTNER HERMANN
摘要:The invention relates to a synchronous CCU method (carbon dioxide capture and utilisation) for the absorption of carbon dioxide from flue gas and other CO 2 -containing substance sources and simultaneous synthesis of dialkyl carbonates and alkylene carbonates. The general subject matter of the invention is, in terms of a 'carbon dioxide capture' on the one hand, the absorption of CO 2 from flue gas and other CO 2 -containing substance sources with ammonia and/or amines to form ammonium carbamates or ammonium hydrogen carbonates or ureas or urea intermediates and, in terms of a 'carbon dioxide utilisation' on the other hand, the reaction of ammonium carbamates or ammonium hydrogen carbonates or ureas or urea intermediates with aliphatic, alicyclic or unsaturated alcohols, and including unsaturated aromatic alcohols to give dialkyl carbonates or alkylene carbonates in such a form that the CO 2 n absorption agent is re-released and fed back into the repetitive process again. A repetitive process control is extremely energy and CO 2 n efficient.

专利号:US-6939962-B2
优先权日:2000-07-31
标题:Method for the synthesis of sucrose-6-esters
发明人:CLARK JASON D; LEMAY JR RICHARD R
权利人:TATE & LYLE PLC
摘要:There is described a process for the synthesis of a sucrose-6-ester comprising: (a) reacting a mixture comprising sucrose and a polar aprotic solvent with an organotin-based acylation promoter, while adding a solvent capable of removing water by co-distillation, and removing water by co-distillation, to afford a first reaction mixture which is substantially free from water, followed by (b) adding a carboxylic anhydride to said first reaction mixture to afford a second reaction mixture, and maintaining said second reaction mixture at a temperature and for a period of time sufficient to produce a sucrose-6-ester, characterised in that step (a) is performed at a temperature of from 85 to 125° C. and at a pressure of from 20 to 80 kPa. In the most preferred embodiment, the polar aprotic solvent is DMF, the solvent capable of removing water by co-distillation is cyclohexane, the organotion-based acylation promoter is a 1,3-diacyloxy-1,1,3,3-tetrabutyldistannoxane, and step (a) is performed at approximately 97° C., and approximately 50 kpa, until the weight ratio of tin to water in the first reaction mixture is greater than about 26, when the tin content is measured by X-Ray Fluoresence Analyzer, and the water content is measured by the Karl-Fischer method.

专利号:US-4680393-A
优先权日:1986-05-08
标题 :Process for the selective synthesis of tertiary alkanolamines
发明人:MARSELLA JOHN A
权利人:AIR PRODUCTS AND CHAMICALS INC
摘要:The present invention is a process for the synthesis of tertiary alkanolamines by reacting a secondary amine with an alkanediol. High selectivity for the production of alkanolamines is achieved by carrying out the reaction in the presence of a compound or complex of ruthenium in chemical combination or in admixture with an organic phosphine ligand. The organic phosphine ligand is present in an amount such that the ratio of gram mole ligand/gram atom ruthenium is greater than 5.

专利号:US-9981935-B2
优先权日:2013-07-05
标 题:Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of acids
发明人:MEDLOCK JONATHAN ALAN; LETINOIS ULLA; NETSCHER THOMAS; BONRATH WERNER
权利人:DSM IP ASSETS BV
摘要:The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of a specific type and of at least one Bransted acid or in the presence a specific chiral compound having a Bransted acid functional group in the molecule.
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合成参考文献


参考文献:10.1107/s1600536811009950
摘要:Biermann M, Hardcastle KI, Moskalev NV, Crooks PA. (S)-2-Amino-2-(2-chloro-phen-yl)cyclo-hexa-none. Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 01;67(Pt 4):o936.
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