CAS: 34781-86-7; 4-Aminobenzene-1,3-Diol Hydrochloride

该化合物是一种有机化合物,其特点是氨基和羟基功能组,有助于其在水中产生反应和溶解,似乎是白色的脱白晶粉,以其染色中间体和各种化学合成中的角色著称,氨基氨基氨基氨组的存在允许其参与各种反应,包括电益芳香替代和混合反应,使其在产生zo染料时具有价值,其盐酸盐形式增强了其在水溶中的溶解性,促进了其在生物和化学应用中的使用.此外,4-氨基索尔盐酸盐展示了潜在的生物活动,从而导致对其药理特性进行调查.然而,在处理该化合物时,应注意安全防范,因为如果浸入或吸入,可能会对健康造成危害.

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    专利信息


    专利号:US-5194562-A
    优先权日:1989-02-22
    标题:Nucleophilic displacement method for synthesis of non-rigid PBZ polymers
    发明人:INBASEKARAN MUTHIAH N; MULLINS MICHAEL J
    权利人:DOW CHEMICAL CO
    摘要:Azole rings, such as oxazole and thiazole rings, can activate an aromatic ring bonded to a leaving group such as a halogen atom so that the aromatic ring will undergo aromatic nucleophilic substitution. The reaction is useful for making ethers, thioethers and amines containing azole rings. In particular, monomers having azole rings, activated aromatic rings with leaving groups and nucleophilic moieties can react under conditions of aromatic nucleophilic displacement to form non-rigid rob PBZ polymers. The non-rigid rod PBZ polymers can be used to form molecular composites with rigid rod PBZ polymers which molecular composites are not substantially phase separated.

    专利号:US-5216110-A
    优先权日:1989-02-22
    标题 :Monomers useful in nucleophilic displacement synthesis of polybenzazole polymers
    发明人:INBASEKARAN MUTHIAH N; MULLINS MICHAEL J
    权利人:DOW CHEMICAL CO
    摘要:Azole rings, such as oxazole and thiazole rings, can activate an aromatic ring bonded to a leaving group such as a halogen atom so that the aromatic ring will undergo aromatic nucleophilic substitution. The reaction is useful for making ethers, thioethers and amines containing azole rings. In particular, monomers having azole rings, activated aromatic rings with leaving groups and nucleophilic moieties can react under conditions of aromatic nucleophilic displacement to form non-rigid rod PBZ polymers. The non-rigid rod PBZ polymers can be used to form molecular composites with rigid rod PBZ polymers which molecular composites are not substantially phase separated.

    专利号:US-5104960-A
    优先权日:1989-02-22
    标 题:Nucleophilic displacement method for synthesis of non-rigid PBZ polymers
    发明人:INBASEKARAN MUTHIAH N; MULLINS MICHAEL J
    权利人:DOW CHEMICAL CO
    摘要:Azole rings, such as oxazole and thiazole rings, can activate an aromatic ring bonded to a leaving group such as a halogen atom so that the aromatic ring will undergo aromatic nucleophilic substitution. The reaction is useful for making ethers, thioethers and amines containing azole rings. In particular, monomers having azole rings, activated aromatic rings with leaving groups and nucleophilic moieties can react under conditions of aromatic nucleophilic displacement to form non-rigid rod PBZ polymers. The non-rigid rod PBZ polymers can be used to form molecular composites with rigid rod PBZ polymers which molecular composites are not substantially phase separated.

    专利号:US-7067554-B2
    优先权日:2000-05-30
    标 题 :Method for the synthesis of compounds of formula I and their uses thereof
    发明人:MJALLI ADNAN M M; GOPALASWAMY RAMESH; AVOR KWASI A; WYSONG CHRISTOPHER L; ANDREW PATRON
    权利人:TRANSTECH PHARMA INC
    摘要:This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, their use in treating human or animal disorders. The compounds of the invention are useful as modulators of the interaction between the receptor for advanced glycated end products (RAGE) and its ligands, such as advanced glycated end products (AGEs), S100/calgranulin/EN-RAGE, β-amyloid and amphoterin, and for the management, treatment, control, or as an adjunct treatment for diseases in humans caused by RAGE. Such diseases or disease states include acute and chronic inflammation, the development of diabetic late complications such as increased vascular permeability, nephropathy, atherosclerosis, and retinopathy, the development of Alzheimer's disease, erectile dysfunction, and tumor invasion and metastasis.

    专利号:AU-2005200425-A1
    优先权日:2000-05-30
    标题 :A method for the synthesis of compounds of formula 1 and their uses thereof

    专利号:US-2006189578-A1
    优先权日:2000-05-30
    标题:Method for the synthesis of compounds of formula I and their uses thereof
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    主要参考文献

    [参考文献]: M J Pacheco, Et Al. Electrochemical Degradation Of Aromatic Amines On Bdd Electrodes. J Hazard Mater. 2011 Feb 28;186(2-3):1033-41.

    合成参考文献


    摘要:Schnürch, M.; Hämmerle, J.; Stanetty, P., Science of Synthesis Knowledge Updates, (2010) 1, 159.
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