CAS: 54314-84-0; ((3-Bromopropoxy)Methyl)Benzene

上下游产品

CAS号4799-68-2 3-苄氧基-1-丙醇 | CAS号108-86-1 溴苯 | CAS号14593-43-2 烯丙基苄基醚 | CAS号100-39-0 溴化苄 | CAS号627-18-9 3-溴-1-丙醇 | CAS号100-44-7 氯化苄 | CAS号98518-10-6 methanesulfonic... | CAS号772-01-0 1,3-Dioxane, 2-... | CAS号100-52-7 苯甲醛 | CAS号54314-85-1 (3-苄氧基丙基)三苯基溴化鏻 | CAS号146450-45-5 ethyl 3-oxo-7-p... | CAS号1210-34-0 5-羟基-10,11-二氢-5... | CAS号937-61-1 (propoxymethyl)... | CAS号95532-05-1 2-methyl-5-phen...

3-苄氧基-1-丙醇置于lithium Bromide体系中,用 三乙胺,丙酮 作为反应溶剂,化学反应 0.25H,反应生成 3-苄氧基溴丙烷
参考文献:通过分子内酯烯醇化物烷基化反应在环己烷环形成中的折叠应变立体控制
标题:通过分子内酯烯醇化物烷基化反应在环己烷环形成中的折叠应变立体控制
摘要:通过 Lda 处理,研究了 7-溴-2-甲基庚酸乙酯与链中不同位置的附加取代基环化的非对映选择性.
DOI:10.1139/v96-279

专利信息

专利号:US-6268499-B1
优先权日:1998-08-10
标 题 :Process and intermediates for preparation of substituted piperidine-epoxides
发明人：GUELLER ROLF; LOHRI BRUNO; SCHMID RUDOLF
权利人:HOFFMANN LA ROCHE
摘要:The present invention concerns intermediates useful in and a process for the preparation of a compound of formula 1 or a salt thereof n comprisingepoxidation of a compound of formula 2 or a salt thereof n wherein A, R 1 and R 2 are as herein defined. These compounds are useful in the synthesis of renin inhibitors.

专利号:US-8067460-B2
优先权日:2004-10-04
标 题 :5-phenoxyalkoxypsoralens and methods for selective inhibition of the voltage gated Kv1.3 potassium channel
发明人：WULFF HEIKE; SANKARANARAYANAN ANANTHAKRISHNAN; HAENSEL WOLFRAM; SCHMITZ ALEXANDER; SCHMIDT-LASSEN KRISTINA
权利人:WULFF HEIKE; SANKARANARAYANAN ANANTHAKRISHNAN; HAENSEL WOLFRAM; SCHMITZ ALEXANDER; SCHMIDT-LASSEN KRISTINA; UNIV CALIFONIA
摘要:Compositions of matter comprising 5-phenoxyalkoxypsoralen compounds and their method of synthesis and use. The compounds are useable to treat diseases or disorders in human or animal subjects, including autoimmune diseases. The compounds inhibit potassium channels, including the Kv1.3 channel and at least some of the therapeutic effects of such compounds may be due at least in part to potassium channel inhibition. In some embodiments, the compounds are more selective for certain potassium channels (e.g., Kv1.3 channels) than other potassium channels (e.g., Kv1.5 channels).

专利号:EP-1399406-B1
优先权日:2001-01-04
标题:Novel estrogen receptor ligands and methods i
发明人：KOEHLER KONRAD; HENSSEN CECILIA; NILSSON MARITA; GILLNER MIKAEL; LIU YE; SANIN ANDREI; WILKENING ROBERT R; RATCLIFFE RONALD W; WENSBO DAVID
权利人:KAROBIO AB; MERCK & CO INC
摘要:The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant inventive are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restinosis, gynecomastia, autoimmune disease, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer of the lung, colon, breast, uterus, and prrostate.

专利号:US-9133224-B2
优先权日:2010-11-29
标 题:Macrocyclic kinase inhibitors
发明人：CREW ANDREW P; DONG HANQING; FERRARO CATERINA; SHERMAN DAN; SIU KAM W
权利人:CREW ANDREW P; DONG HANQING; FERRARO CATERINA; SHERMAN DAN; SIU KAM W; OSI PHARMACEUTICALS LLC
摘要:Compounds of Formula (I): wherein variables are defined herein, and pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancers for which FAK inhibition is beneficial.