CAS: 9034-50-8; N-(1-((2-Amino-2-Oxoethyl)Amino)-5-((Diaminomethylene)Amino)-1-Oxopentan-2-yl)-1-(19-Amino-7-(2-Amino-2-Oxoethyl)-10-(3-Amino-3-Oxopropyl)-13-(Sec-Butyl)-16-(4-Hydroxybenzyl)-6,9,12,15,18-Pentaoxo-1,2-Dithia-5,8,11,14,17-Pentaazacycloicosane-4-Carbonyl)Pyrrolidine-2-Carboxamide

专利信息

专利号:US-6420110-B1
优先权日:1998-10-19
标 题 :Methods and reagents for isolating biologically active peptides
发明人：GYURIS JENO; MORRIS AARON J
权利人:GPC BIOTECH INC
摘要:One aspect of the present invention is the synthesis of a binary method that combines variegated peptide display libraries, e.g., in a “display modeâ€?, with soluble secreted peptide libraries, e.g., in a “secretion modeâ€?, to yield a method for the efficient isolation of peptides having a desired biological activity.

专利号:US-2002025536-A1
优先权日:2000-06-26
标 题:Methods and reagents for isolating biologically active antibodies
发明人：GYURIS JENO; EWERT SEBASTIAN-MEIER; NAGY ZOLTON; MORRIS AARON
摘要:One aspect of the present invention is the synthesis of a binary method that combines variegated antibody display libraries, e.g., in a “display modeâ€?, with soluble secreted antibody libraries, e.g., in a “secretion modeâ€?, to yield a method for the efficient isolation of antibodies having a desired biological activity.

专利号:US-7052692-B1
优先权日:1997-09-02
标题:Role of tyrosine phosphorylation of a cellular protein in adeno-associated virus 2-mediated transgene expression
发明人：SRIVASTAVA ARUN; QING KEYUN; WANG XU-SHAN; PONNAZHAGAN SELVARANGAN; BAJPAI ANIL
权利人:ADVANCED RES & TECH INST
摘要:The present invention identifies a protein, designated the D-sequence-binding protein (D-BP), is phosphorylated at tyrosine residues and blocks AAV-mediated transgene expression in infected cells by inhibiting the leading strand viral DNA synthesis. More particularly, the present invention demonstrates that D-BP is phosphorylated by EGF-R protein tyrosine kinase. Methods of increasing transcription and promoting replication of transgenes exploiting this information are disclosed herein.

专利号:US-7045503-B1
优先权日:1996-07-12
标 题 :Radiometal-binding peptide analogues
发明人：MCBRIDE WILLIAM J; GRIFFITHS GARY L
权利人:IMMUNOMEDICS INC
摘要:Novel metal binding ligands are disclosed that may be coupled to peptides for use in methods of diagnosis and therapy. Peptides containing the ligands are produced using a method wherein ligand introduction or cyclization can be conducted at any point during the synthesis of the peptide. Such peptide derivatives are readily labeled with radiometals, such as isotopes of rhenium or technetium, while retaining their ability to tightly bind specific peptide receptors.

专利号:CN-103374054-A
优先权日:2012-04-28
标 题:Method for one-step solid-phase synthesis of polypeptide

专利号:PT-710243-E
优先权日:1993-06-29
标题:IMPROVED SYNTHESIS OF CYCLIC PEPTIDOS.