CAS: 200623-62-7; Fmoc-D-Gln(Trt)-Oh

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102747-84-2 112898-00-7 132327-80-1

上下游产品

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 5-trityl-L-glutamine triphenylmethyl alcohol L-glutamineFm°C-Gln(Trt)-OPfp Fm°C-Gln(trityl) 2,4,5-trichlorophenyl ester

专利信息

专利号:US-2025011366-A1
优先权日:2021-09-08
标 题:Prodrugs of Antibiotic Teixobactin
发明人：JONES CHELSEA R; NOWICK JAMES S
权利人:UNIV CALIFORNIA
摘要:Prodrugs of antibiotic teixobactin, methods of their synthesis, and methods of their use as antimicrobial treatments are described. The teixobactin prodrugs incorporate one or more O-acyl linkages. The O-acyl linkages can be utilized in substitution of amide peptide bonds between an amino acid containing an alcohol side chain and the immediately preceding amino acid.

专利号:US-6660832-B1
优先权日:1999-08-20
标题:Macrocyclic compounds and preparation methods thereof
发明人：JEFFERSON ELIZABETH; SWAYZE ERIC EDWARD
权利人:ISIS PHARMACEUTICALS INC
摘要:The present invention is directed to macrocyclic compounds of the formula (I)wherein Q, X, R1 and R5 are as defined herein. Compounds of the invention are useful for therapeutic and prophylactic treatment of bacterial infection in mammals. Solid phase synthetic procedures are provided effecting synthesis of the macrocyclic rings attached to a solid support.

专利号:US-11897970-B2
优先权日:2017-03-09
标 题 :Antibacterial products
发明人：SINGH ISHWAR; TAYLOR EDWARD
权利人:UNIV LIVERPOOL
摘要:The invention provides novel antibacterial compounds of formulae IA, IB and IC as defined herein. Optionally, the antibacterial compounds can be bonded to a delivery agent that is capable of bonding to one or more structures on a bacterial cell membrane. The invention also provides the use of such compounds in treating or preventing bacterial infections, and processes for their synthesis.