CAS: 4559-70-0; Diphenylphosphine Oxide

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CAS号791-28-6 三苯基氧化膦 | CAS号34117-90-3 2-氨基-3-氯喹喔啉 | CAS号829-85-6 二苯基膦 | CAS号1079-66-9 氯代二苯基膦 | CAS号172487-18-2 phenylphosphini... | CAS号591-51-5 苯基锂 | CAS号100-58-3 苯基溴化镁 | CAS号2213-63-0 2,3-二氯喹喔啉 | CAS号53772-44-4 diphenyl-phenyl... | CAS号10557-66-1 dibutylphosphor... | CAS号4233-13-0 [butyl(phenyl)p... | CAS号43077-30-1 DPO-1,KV1.5和IKu... | CAS号5931-53-3 二苯基(o-甲苯基)膦 | CAS号4141-48-4 烯丙基联苯氧化膦 | CAS号402822-70-2 2-二苯基膦-2'-甲氧基联苯 | CAS号41593-58-2 硼烷二苯基膦络合物 | CAS号402822-72-4 2-二苯基磷-2'-甲基联苯 | CAS号4455-77-0 甲氧甲基(二苯基)氧化膦 | CAS号23040-22-4 (DIPHENYLPHOSPH...

专利信息

专利号:US-7301006-B2
优先权日:2002-07-16
标 题 :Methods and materials for the synthesis of modified peptides
发明人：YOUNG TRAVIS G; KIESSLING LAURA L
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Methods and protected amino acids useful as building blocks (protected monomers) for the synthesis of peptides and proteins that are selectively modified at one or more side-chain hydroxyl groups. Azide-bearing protecting groups allow the selective deprotection of side-chain hydroxyl groups of amino acids after synthesis of a peptide. Reaction conditions for removal of the azide-bearing protecting group can be selected which are substantially orthogonal to those that will remove α-amino protecting groups typically employed in peptide synthesis, such that hydroxyl groups protected with the azide-bearing protecting group remain protected during synthesis of the peptide chain. Various protecting groups which are readily available can be used for protecting potentially reactive side chain groups of amino acids in the peptide or protein to be modified. Preferred side-chain protecting groups are chemically distinguishable from the azide-bearing protecting group and substantially orthogonal reaction conditions can be selected such that side-chain protection of other amino acids is maintained when the azide-bearing protecting group is removed. The use of the azide-bearing protecting group of this invention for one or more hydroxy amino acids during peptide synthesis allows the selective unmasking of those azide-protected side-chain hydroxyl groups and selective modification of the hydroxyl groups that are selectively unmasked. The methods and materials herein are particularly used in synthesis of sulfated, phosphorylated and glycosylated peptides and proteins. Kits and methods of synthesizing a modified peptide or protein using the kits are also provided.

专利号:US-7230101-B1
优先权日:2002-08-28
标 题:Synthesis of methotrexate-containing heterodimeric molecules
发明人：MURTHI KRISHNA K; SMITH CHASE C
权利人:GPC BIOTECH INC
摘要:The present invention relates to novel compositions of methotrexate-containing heterodimeric probe molecules, also known as chemical inducers of dimerization (CID), useful in three-hybrid assays. The invention further relates to synthesis of said compositions and their intermediates. Another aspect of the invention is a method for using the heterodimeric probe molecules described herein in drug screens to identify potential protein targets to a given ligand, optimize protein-ligand interactions, or identify potential ligands for a given protein target. In certain embodiments, the invention contemplates the synthesis of the following methotrexate-containing heterodimeric probe:

专利号:US-2025026768-A1
优先权日:2023-06-30
标题:Method for the synthesis of axially chiral organoboron compounds
发明人：PING YIFAN; CHE CHI-MING
权利人:LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LTD
摘要:A highly efficient and atroposelective Rh-catalyzed [2+2+2] cycloaddition for the synthesis of axially chiral aryboron compounds is developed. The reactions of diynes and alkynylborons smoothly occur in an atom-economical manner, affording a variety of C—B atropisomers in excellent yields and enantioselectivities. The protocol features mild conditions, broad substrate scope, and good functional tolerance. The obtained C—B atropisomers show powerful synthetic applications in terms of producing novel chiral phosphine ligands.

专利号:US-8450365-B2
优先权日:2009-05-12
标 题 :Efficient synthesis of galanthamine
发明人：MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ
权利人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ; UNIV TEXAS
摘要:The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine related derivatives and intermediates thereof. In further embodiments, the invention relates to methods for improving the efficiency and overall yield of galanthamine and intermediates thereof.

专利号:US-11370736-B2
优先权日:2019-04-01
标 题:Synthesis of fluoro hemiacetals via transition metal-catalyzed fluoro ester and carboxamide hydrogenation
发明人：DUB PAVEL A; BATRICE RAMI J; GORDON JOHN C
权利人:TRIAD NAT SECURITY LLC
摘要:This application is directed to use of transition metal-ligand complexes to hydrogenate fluorinated esters and carboxamides into fluorinated hemiacetals. Methods for synthesis of certain ligands are also provided.

专利号:EP-3560936-A1
优先权日:2018-04-24
标题:Method for the synthesis of alkenyl-phosphorous compounds
发明人：SCHÄFER SASCHA WILHELM; ZHAO LIGANG; STUDER AMIDO
权利人:HENKEL AG & CO KGAA
摘要:The invention pertains to a method for the synthesis of specific alkenyl-phosphorous compounds according to formula (I)whereinR¹and R²are independently selected from hydrogen or a substituted or unsubstituted C_1-40hydrocarbon group, whereby the group optionally contains at least one heteroatom, preferably O, N or S;X is independently O or S;R³and R⁴are independently selected from a substituted or unsubstituted C_1-40hydrocarbon group, whereby the group optionally contains at least one heteroatom, preferably O, N or S;m is independently 0 or 1; andn is an integer from 1 to 4. Furthermore, the invention relates to compounds obtained by this method, and compositions comprising the compounds of the present invention, wherein the compositions are compositions for lighting applications, optical applications, microelectronic compounds, optical brighteners or are detergent compositions. Finally, the invention relates to the use of the compounds of the present invention in lighting lighting applications, optical applications microelectronic compounds, optical brighteners or detergent compositions.