CAS: 2386-60-9; 1-Butanesulfonylchloride

相似化合物

10147-36-1 22795-37-5 1633-84-7

上下游产品

CAS号109-79-5 正丁硫醇 | CAS号629-45-8 二丁基二硫醚 | CAS号2386-54-1 丁烷磺酸钠 | CAS号2386-47-2 1-丁磺酸 | CAS号55716-09-1 S,S'-di-n-butyl... | CAS号693-04-9 正丁基氯化镁 | CAS号18939-69-0 2-butylisothiou... | CAS号5184-47-4 butylsulfanylme... | CAS号628-83-1 硫氰酸丁酯 | CAS号544-40-1 二丁基硫醚 | CAS号375-72-4 全氟丁基磺酰氟 | CAS号14673-97-3 1-Butanesulfona... | CAS号14673-98-4 N,N-dibutylbuta... | CAS号204992-21-2 (2,5-dioxopyrro... | CAS号629-45-8 二丁基二硫醚 | CAS号78-40-0 磷酸三乙酯 | CAS号20195-07-7 o,o-Diethyl S-b... | CAS号75-00-3 氯乙烷 | CAS号109-79-5 正丁硫醇 | CAS号2374-59-6 1-Butanesulfona...

丁硫醇置于1,3-二氯-5,5-二甲基海因,水,苄基三甲基氯化铵体系中,用 乙腈 用作溶剂,化学反应 0.5H,反应生成1-丁基磺酰氯
参考文献:使用 1,3-二氯-5,5-二甲基乙内酰脲 (Dch) 从硫醇和二硫化物方便地一锅法合成磺胺
标题:使用 1,3-二氯-5,5-二甲基乙内酰脲 (Dch) 从硫醇和二硫化物方便地一锅法合成磺胺
摘要:描述了从硫醇和二硫化物方便合成磺胺类药物.从硫醇原位制备磺酰氯是通过在 N苄基-三甲基氯化铵和水下用 1,3-二氯-5,5-二甲基乙内酰脲 (Dch) 氧化来完成的.然后进一步使磺酰氯在同一反应容器中与过量胺反应.
Doi:10.5012/bkcs.2012.33.2.383

专利信息

专利号:US-5512701-A
优先权日:1995-06-07
标题:Process for the synthesis of vinyl sulfenic acid derivatives
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfenic acid derivatives. These compounds are useful for the synthesis of benzo[b]thiophenes, in particular 2-aryl-benzo[b]thiophenes.

专利号:US-6639059-B1
优先权日:1999-03-24
标 题 :Synthesis of [2.2.1]bicyclo nucleosides
发明人：KOCHKINE ALEXEI; FENSHOLDT JEF; PFUNDHELLER HENRIK M
权利人:EXIQON AS
摘要:A synthesis of [2.2.1]bicyclo nucleosides which is shorter and provides higher overall yields proceeds via the key intermediate of the general formula III, wherein R4 and R5 are, for instance, sulfonates and R7 is, for instance, a halogen or an acetate. From compounds of the general formula II, such as 3-O-aryl-4-C-hydroxymethyl-1,2-O-isopropylidene-alpha-D-ribofuranose, intermediates of the general formula III are suitable for coupling with silylated nucleobases. Upon one-pot base-induced ring-closure and desulfonation of the formed [2.2.1]bicyclo nucleoside, a short route to each the LNA (Locked Nucleic Acid) derivatives of adenosine, cytosine, uridine, thymidine and guanidine is demonstrated. The use of the 5'-sulfonated ring-closed intermediate also allows for synthesis of 5'-amino- and thio-LNAs.

专利号:US-6734291-B2
优先权日:1999-03-24
标题:Synthesis of [2.2.1]bicyclo nucleosides
发明人：KOCHKINE ALEXEI; FENSHOLDT JEF; PFUNDHELLER HENRIK M
权利人:EXIQON AS
摘要:A synthesis of [2.2.1]bicyclo nucleosides which is shorter and provides higher overall yields proceeds via the key intermediate of the general formula III, wherein R4 and R5 are, for instance, sulfonates and R7 is, for instance, a halogen or an acetate. From compounds of the general formula II, such as 3-O-aryl-4-C-hydroxymethyl-1,2-O-isopropylidene-alpha-D-ribofuranose, intermediates of the general formula III are suitable for coupling with silylated nucleobases. Upon one-pot base-induced ring-closure and desulfonation of the formed [2.2.1]bicyclo nucleoside, a short route to each the LNA (Locked Nucleic Acid) derivatives of adenosine, cytosine, uridine, thymidine and guanidine is demonstrated. The use of the 5'-sulfonated ring-closed intermediate also allows for synthesis of 5'-amino- and thio-LNAs

专利号:US-6372945-B1
优先权日:1995-06-07
标 题 :Process for the synthesis of vinyl sulfoxides
发明人：AIKINS JAMES A; MILLER RANDAL SCOT; ZHANG TONY Y
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfoxides, in particular diarylvinyl sulfoxides

专利号:US-5606076-A
优先权日:1995-06-07
标 题 :Process for the synthesis of benzo[b]thiophenes
发明人：AIKINS JAMES A; ZHANG TONY Y
权利人:LILLY CO ELI
摘要:The present invention is directed to a process for the synthesis of 2-arylbenzo[b]thiophenes.

专利号:US-5569772-A
优先权日:1995-06-07
标 题:Process for the synthesis of benzo[b]thiophenes
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of 2-aryl benzo[b]thiophenes, and to novel intermediates therefor.