CAS: 262587-05-3; 1-Bromo-3-(Difluoromethoxy)Benzene

上下游产品

3-Bromophenol sodium chlorodifluoroacetate 2-(3-bromophenoxy)-2-fluoroacetic acid ethyl (3-bromophenoxy)(fluoro)acetate 2-(3-(difluoromethoxy)phenyl )-4,4,5,5-tetramethyl-1,3,2-dioxaborolane N-(5-(3-(difluoromethoxy)phenyl)-2-morpholinopyridin-4-yl)-5,7-difluoro-3-methyl-2-(pyridin-2-yl)quinolin-4-amine 4-(3-difluoromethoxyphenylthio)-2,5-xylidine N-ethyl-N-methyl-N'-[4-(3-difluoromethoxyphenylthio)-2,5-xylyl]formamidine

间溴苯酚置于二氟代氙,Potassium Carbonate体系中,用 甲醇,氘代氯仿,水,N,N-二甲基甲酰胺 用作溶剂,化学反应 0.33H,反应生成1-溴-3-(二氟甲氧基)苯
参考文献:二氟化氙介导的氟代羧化反应合成二氟和三氟甲氧基芳烃
标题:二氟化氙介导的氟代羧化反应合成二氟和三氟甲氧基芳烃
摘要:在单和二氟芳氧基乙酸衍生物的氟脱羧反应中,Xef 2被证明是比nfsi或selectfluor更有效的氟转移试剂.该方法有效地转化了多种中性和电子贫乏的底物,以非常好至极好的收率提供了所需的二氟和三氟甲基芳基醚.纯化很容易,反应时间少于5分钟,这使得这些氟代脱羧有希望用于未来的pet成像应用.
Doi:10.1021/acs.Orglett.6B02208

专利信息

专利号:WO-2024022910-A1
优先权日:2022-07-26
标题 :1-[1-[2-(pyrimidin-4-yl)-1,2,4-triazol-3-yl]ethyl]-3-[2,4-dichloro-5-phenyl]urea derivatives and similar compounds as pesticides
发明人：WEISS MATTHIAS; JEANGUENAT ANDRE; KILARU JAGADEESH PRATHAP; MUEHLEBACH MICHEL; SCARBOROUGH CHRISTOPHER CHARLES; STOLLER ANDRé; SUESSE LARS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to compounds of formula (I) wherein: X is O or S; Q is Q a or Q b as pesticides and insecticides. Preferred compounds are e.g. 1-[1-[2-(pyrimidin-4-yl)-1,2,4-triazol-3-yl]ethyl]-3-[2,4-dichloro-5-phenyl]urea derivatives and similar compounds. An exemplary compound is e.g. 1-[(1S)-1-[2-(6-cyanopyrimidin-4-yl) -1,2,4-triazol-3-yllethyll-3-[2,4-dichloro-5-(trifluoromethyl)phenyllurea (example E1; compound P1). The present invention discloses the synthesis and characterisation of exemplary compounds as well as biological data thereof.