CAS: 34256-82-1; Acetochlor

该化合物是一种选择性除草剂,主要用于控制各种作物,特别是玉米和大豆的年草和某些大叶杂草,属于氯乙酸类除草剂,其作用是抑制脂肪酸合成,干扰目标植物生长;甲草胺的特征是其相对低的挥发性和高脂性,允许其在土壤中长期持续并有效控制杂草;通常在出现前或早期出现后应用该物质,以尽量提高其效力;该物质对浅色黄色的,有温味的液体是无色的,在水中具有中度溶性,因此必须考虑其环境影响,特别是在地下水污染方面;在处理甲草胺时,安全措施至关重要,因为如果不按照准则使用,它可能会对人类健康和非目标生物构成危险;监管评估确定了可接受的接触水平,以确保安全农业做法.

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CAS号56917-59-0 N-(2-methyl-6-e... | CAS号79-11-8 氯乙酸 | CAS号32428-71-0 2-乙基-6-甲基-N-氯乙酰基苯胺 | CAS号3188-13-4 氯甲基乙醚 | CAS号161499-20-3 2-chloro-N-(eth...

合成工艺路线路线简述

    2-Chloro-N-(Ethoxymethyl)-N-(2-Ethyl-4-Iodo-6-Methylphenyl)Acetamide置于palladium On Activated Charcoal 氢气,三乙胺体系中,用 乙醇 作为反应溶剂,化学反应 3.0H,以14 Mg的收率获得产物乙草胺
    参考文献:Radiosynthesis Of A Chloroacetanilide Herbicide ([phenyl-4-3H] Acetochlor) And A Dichloroacetamide Safener For Herbicides ([2,2-Dimethyl-3H]R-29148)
    标题:Radiosynthesis Of A Chloroacetanilide Herbicide ([phenyl-4-3H] Acetochlor) And A Dichloroacetamide Safener For Herbicides ([2,2-Dimethyl-3H]R-29148)
    摘要:2-氯-N-(乙氧基甲基)-N-(2-乙基-6-甲基苯基)乙酰胺(氯乙酰苯胺除草剂乙草胺)和3-(二氯乙酰基)-2,2,5-三甲基-1,3-恶唑烷(二氯乙酰胺安全剂r-29148)需要高比活度,用于研究其代谢和作用方式.在碳钯和三乙胺的作用下,碘乙草胺在乙醇中与氚气发生还原脱卤反应,得到[苯基-4-3H]乙草胺,产率为71%,浓度为22 Ci/mmol.在五烷中,用等量的naoh处理丙酮和1-氨基-2-丙醇,得到[2,2-二甲基-3H]R-29148,浓度为15 Ci/mmol,然后在二氯乙酰氯的作用下,得到[2,2-二甲基-3H]R-29148.
    DOI:10.1002/jlcr.2580360207

    海关参考信息

    专利信息


    专利号:WO-2024256370-A1
    优先权日:2023-06-13
    标 题 :Synthesis of glufosinate using an amidase-based process
    发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

    专利号:US-2025120400-A1
    优先权日:2021-12-10
    标题:Synthesis of glufosinate using a hydantoinase-based process
    发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

    专利号:US-11078093-B2
    优先权日:2017-06-30
    标 题 :Surfactant-assisted synthesis of surface-functionalized nanoparticle-polymer electrospun composites
    发明人:CWIERTNY DAVID; MYUNG NOSANG; PETER KATHERINE T; PARKIN GENE FRANCIS
    权利人:UNIV CALIFORNIA; UNIV IOWA RES FOUND
    摘要:A method is disclosed for synthesizing nanofilters for water treatment. The method includes: dispersing an active binding agent in an organic solvent solution to create a suspension of the active binding agent and the solution of the solvent; dissolving an organic polymer resin and an anionic surfactant in the suspension of the active binding agent and the solvent solution to create a sol gel; and electrospinning the sol gel to form electrospun nanofiber composites with embedded, surface-active nanoparticles.

    专利号:US-11919928-B2
    优先权日:2016-03-16
    标题 :Method for producing dihydrotentoxin
    发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
    权利人:KUMIAI CHEMICAL INDUSTRY CO
    摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

    专利号:US-2021386068-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

    专利号:US-2021352899-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.
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    主要参考文献


    1: Qin X, Jiang Y, Wang Z, Man C, Fu S, Chen S, Yang X, Yang T, Zhang D, Li L, Fox EM, Zhang W. The migration of acetochlor from feed to milk. RSC Adv. 2020 Dec 15;10(72):44344-44351. doi: 10.1039/d0ra06895k.
    2: Zhang Y, Xue W, Long R, Yang H, Wei W. Acetochlor affects zebrafish ovarian development by producing estrogen effects and inducing oxidative stress. Environ Sci Pollut Res Int. 2020 Aug;27(22):27688-27696. doi: 10.1007/s11356-020-09050-2. Epub 2020 May 11.
    833:155239. doi: 10.1016/j.scitotenv.2022.155239. Epub 2022 Apr 11.

    合成参考文献


    参考文献:10.1007/s00216-005-0167-6
    摘要:Ibáñez M, Sancho JV, Pozo ÓJ, Hernández F. Use of liquid chromatography quadrupole time-of-flight mass spectrometry in the elucidation of transformation products and metabolites of pesticides. Diazinon as a case study. Analytical and Bioanalytical Chemistry. 2005 Dec 01;384(2):448–57. doi: 10.1007/s00216-005-0167-6.
    参考文献:10.3390/ijerph8062265
    摘要:Mnif W, Hassine AI, Bouaziz A, Bartegi A, Thomas O, Roig B. Effect of endocrine disruptor pesticides: a review. Int J Environ Res Public Health. 2011 Jun;8(6):2265–303.
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