专利号:WO-2025101716-A1 优先权日:2023-11-07 标题:Processes for synthesis of trifunctionalized sulfur(vi) compounds 发明人:LOPCHUK JUSTIN; SHULTZ ZACHARY; ATHAWALE PARESH 权利人:H LEE MOFFITT CANCER CT & RES 摘要:This disclosure describes processes for the asymmetric synthesis of trifunctionalized sulfur(VI) containing organic compounds of Formula I and Formula VI, as well as compounds of Formula I and Formula VI prepared by the processes described.
专利号:US-2005239767-A1 优先权日:2003-10-28 标题 :Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands 发明人:CHAN MICHAEL K; FEKNER TOMASZ 权利人:CHAN MICHAEL K; FEKNER TOMASZ 摘要:A new class of tetracylic benzimidazole compounds and derivatives thereof. Additionally provided is a synthetic route for the generation of these and related compounds via Intramolecular Aromatic Nucleophilic Substitution (S N Ar) of the Benzimidazole-Activated Nitro Groups. Additionally, a facile route for the generation of novel phenol species as thermal decomposition of compounds the S N Ar product, which occurs at high temperature resulting in cleavage of the ether linkage and formation of a vinyl group and phenol is provided. Also provided are methods of using the compounds described herein in the treatment HIV.
专利号:US-6175024-B1 优先权日:1999-03-03 标题 :Synthesis of functionalized esters 发明人:BOYLE JR WILLIAM J; REDDY INDIRA; QIAN ZHENRONG; SU HENG ERIC; RYCKMAN DAVID 权利人:ALLIED SIGNAL INC 摘要:A method of preparing an ester of a carboxylic acid functionalized with a moiety selected from the group consisting of halides, sulfonates, ethers, hydroxyl, amines, and aldehydes, said method comprising: (a) providing either a carboxylic acid having a vinyl group or an ester thereof; (b) functionalizing the vinyl carbon closest to the carboxyl group with said moiety, wherein said functionalizing comprises cleaving said vinyl group.
专利号:US-9175026-B2 优先权日:2011-03-23 标题:Synthesis of thioether containing trialkoxysilanes 发明人:GARRELL ROBIN L; TUCKER-SCHWARTZ ALEXANDER K 权利人:GARRELL ROBIN L; TUCKER-SCHWARTZ ALEXANDER K; UNIV CALIFORNIA 摘要:The invention relates to a radical-initiated thiol-ene or thiol-yne “clickâ€? reaction that provides a simple and efficient route to diverse trialkoxysilanes. Trialkoxysilanes made in this way are obtained in quantitative to near-quantitative yields with high purity without any or minimal purification. A wide range of functional groups is tolerated in this approach, and even complex alkenes click with the silane precursors. The modular nature of these radical-based thiol-ene or thiol-yne “clickâ€? reactions allows a wide variety of pendant groups to be coupled to silane compounds that can then be coupled to a wide variety surfaces in order to modify their material properties. Consequently, such radical initiated thiol-ene and thiol-yne reactions provide facile and efficient methods for preparing an enormous number of surface-active functional trialkoxysilanes.
专利号:US-9782748-B2 优先权日:2008-08-08 标题:Synthesis of polymeric ionic liquids using a photochemical polymerization process 发明人:ANDERSON JARED L 权利人:UNIV TOLEDO 摘要:Photo-initiated polymeric ionic liquids, methods of making and methods of using the same are disclosed. A preferred embodiment for making a photo-initiated polymeric ionic liquid (P-PIL) coated support, comprises: mixing at least one ionic liquid (IL) monomer with at least one photo-initiator; at least partially coating a support with the mixture; and exposing the coated support to UV light to form a photo-initiated polymeric ionic liquid (P-PIL) coated support.
专利号:US-7038072-B2 优先权日:2002-07-24 标 题 :Process for monoalkylation of C-H acidic methylene groups 发明人:BODMANN KERSTIN; MEYER OLIVER; KAUFHOLD MANFRED; FIEKER JUERGEN; PAULCZYNSKI RENATE 权利人:DEGUSSA 摘要:The present invention is directed to a process for the synthesis of monoalkylated C—H acidic methylene group-containing compounds, such as malonic esters, and malonic ester nitriles.
摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1272. 摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1282. 摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 302. 摘要:Ruskin, J.; Lectka, T., Science of Synthesis: Modern Strategies in Organofluorine Chemistry, (2025) 2. 参考文献:10.1007/s00775-004-0550-3 摘要:Lainé M, Richard F, Tarnaud E, Bied-Charreton C, Verchère-Béaur C. Synthesis of novel types of copper-bipyridyl porphyrins and characterization of their interactions and reactivity with DNA. JBIC Journal of Biological Inorganic Chemistry. 2004 May 20;9(5):550–62. doi: 10.1007/s00775-004-0550-3.