专利号:US-7479575-B2 优先权日:2003-10-13 标 题:Method for preparing para-phenyl alkynyl benzaldehydes 发明人:SWINNEN DOMINIQUE; POHIN DANIG 权利人:SERONO LAB 摘要:The present invention is related to a new synthesis for preparing para-phenyl alkynyl benzaldehyde of general formula (I). The compounds of formula (I) are useful building blocks, in particular in the synthesis of electrically conducting polymers. R is selected from the group consisting of C 1 -C 12 -alkyl, C 1 -C 12 -alkyl aryl, C 1 -C 12 -alkyl heteroaryl, C 2 -C 12 -alkenyl, C 2 C 12 -alkenyl aryl, C 2 -C 12 -alkenyl heteroaryl, C 2 -C 12 -alkynyl, C 2 -C 12 -alkynyl aryl, C 2 -C 12 -alkynyl heteroaryl, C 3 -C 8 -cycloalkylC 1 -C 12 -alkyl-C 3 -C 8 -cycloalkyl, C 1 -C 12 -alkoxy, aryl, heteroaryl, halides.
专利号:US-8592458-B2 优先权日:2005-06-07 标 题 :Alpha7 nicotinic receptor selective ligands 发明人:KEM WILLIAM READE; SOTI FERENC 权利人:KEM WILLIAM READE; SOTI FERENC; UNIV FLORIDA 摘要:The invention relates to the design and synthesis of 3-arylidene-anabaseine compounds that exhibit enhanced selectivity toward alpha7 nicotinic receptors. The compounds are expected to be useful in treating a wide variety of conditions, including neurodegenerative conditions such as Alzheimer's Disease, neurodevelopmental diseases such as schizophrenia, and certain peripherally located inflammations mediated by macrophage infiltration.
专利号:US-5523410-A 优先权日:1992-07-02 标 题 :Intermediate for synthesis and production of amino acid derivative 发明人:KAGARA KOOJI; KAWAI NOBUTAKA; MACHIYA KOJI; FURUTERA TETSUO; NAKAMURA TAKASHI; OMORI HIROKI 权利人:FUJISAWA PHARMACEUTICAL CO 摘要:The present invention relates to synthetic intermediates useful for preparing amino acid derivatives possessing renin-inhibitory activity, and to processes for preparing the amino acid derivatives using the synthetic intermediates.
专利号:EP-0648747-A1 优先权日:1992-07-02 标题:Novel intermediate for synthesis and production of amino acid derivative
专利号:CN-116143689-B 优先权日:2023-02-06 标题 :Synthesis method of 2,3,5, 6-tetra-substituted pyridine compound
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