专利号:US-4756739-A 优先权日:1985-12-21 标题 :Pyridine derivatives and the N-oxides thereof, and the use thereof as intermediates for the synthesis of plant protecting agents 发明人:FUSS ANDREAS; KOCH VOLKER 权利人:HOECHST AG 摘要:The compounds of the formula I (I) in which A denotes N or N->O, Z denotes O or NH, R denotes H, (halo)alkyl, (halo)alkenyl, (halo)alkynyl or alkoxycarbonyl, R1 denotes hydrogen, halogen, amino, -NHOH, hydroxyl, (substituted) phenylazo or a radical of the formulae Y=C=N-, Y1Y2C=N-, Y3NH- or K denotes 0 or 1, and m and n, independently of one another, denote a number from 1 to 4, with the proviso that, when Z-R denotes OH or NH2, (R1)n denotes at least one radical of the formula or represents two radicals, in the 5 or 6 position of the heterocyclic ring, which, in the 5 position, denote halogen and, in the 6 position, denote a radical of the group comprising halogen, amino, hydroxyl or phenylazo, which may be substituted as specified above, are valuable intermediates in the synthesis of plant protection agents.
专利号:US-9567307-B2 优先权日:2011-01-07 标题:Amination of aryl alcohol derivatives 发明人:GARG NEIL K; RAMGREN STEPHEN D; SILBERSTEIN AMANDA L; QUASDORF KYLE W 权利人:GARG NEIL K; RAMGREN STEPHEN D; SILBERSTEIN AMANDA L; QUASDORF KYLE W; UNIV CALIFORNIA 摘要:Embodiments of the invention provide methods and materials for chemical cross-coupling reactions that utilize aryl alcohol derivatives as cross-coupling partners. Embodiments of the invention include methods for the amination of aryl sulfamates and carbamates, which are attractive cross-coupling partners, particularly for use in multistep synthesis. Illustrative embodiments include versatile means to use simple derivatives of phenol as precursors to polysubstituted aryl amines, as exemplified by a concise synthesis of the antibacterial drug linezolid.
专利号:US-12435034-B2 优先权日:2020-10-19 标 题 :Process of preparing 3-fluoro-5(((1R,2AR)-3,3,4,4-tetrafluoro-1,2A-dihydroxy-2,2A,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)-oxy)benzonitrile 发明人:FU JIPING; LOU YAN; HE YIGANG; SHI YUETAO; ZHOU PENG; LI XINGXING 权利人:NIKANG THERAPEUTICS INC 摘要:Disclosed herein are processes for preparing certain intermediates useful in the synthesis of 3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a-hydroxy-2,2a,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)oxy)benzonitrile or a pharmaceutically acceptable salt thereof.
专利号:CN-114805660-A 优先权日:2022-05-07 标题 :A kind of synthesis of functionalized trifluorovinyl compound and its resin preparation method
专利号:RU-2602238-C1 优先权日:2015-10-26 标 题:2-bromotetrafluoroethyl chlorine sulfate as semi-finished product for synthesis of bromoethyldifluoroacetate, method of its production and method of producing bromoethyldifluoroacetate
专利号:RU-2505529-C1 优先权日:2012-05-30 标 题 :Synthesis of novel class of fluorine-containing liquid-crystalline compounds with application of chladone 114b2 as initial compound