2-溴苯酚置于硝酸,铁粉,氯化铵,溶剂黄146体系中,用 乙醇,水 用作溶剂,化学反应 8.08H,反应生成4-氯 3-碘-苯甲酸甲酯 参考文献:Heterocyclic Compounds As Adenosine Antagonists 标题:Heterocyclic Compounds As Adenosine Antagonists 摘要:提供了氨基吡嗪化合物作为腺苷受体的调节剂.这些化合物可能作为治疗经由g蛋白偶联受体信号通路介导的疾病的治疗剂,并且可能在肿瘤学中发挥特定作用.
专利信息
专利号:US-2024294532-A1 优先权日:2021-07-12 标题 :Synthesis of chiral substituted pyrazolopyrimidine compounds 发明人:TOMAS LOÃ?C; HARRIS CRAIG STEVEN 权利人:GALDERMA HOLDING S A 摘要:The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of mechanistic target of rapamycin (mTOR).
专利号:CN-108586375-A 优先权日:2018-06-13 标题:A green method for the synthesis of 2-substituted benzoxazole compounds by biocatalytic oxidative cyclization
专利号:WO-2023057548-A1 优先权日:2021-10-07 标题:Ccr6 receptor modulators 发明人:AISSAOUI HAMED; ALLEMANN OLIVER; CAROFF EVA; MEYER EMMANUEL; RICHARD-BILDSTEIN SYLVIA 权利人:IDORSIA PHARMACEUTICALS LTD 摘要:The present invention relates to compounds of Formula (I), their synthesis and use as CCR6 receptor modulators for the prevention or treatment of e.g. inflammatory/autoimmune diseases/disorders and cancer.
摘要:Zhang, H.; Liu, C.; Lei, A., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 146. 摘要:Yi, C. S., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 1, 242. 摘要:Bellina, F.; Perego, L. A., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 760. 摘要:Nakao, Y., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 1, 302.