CAS: 872041-86-6; (5-Fluoropyridin-3-yl)Boronic Acid

相似化合物

719268-92-5 1366482-40-7 1072946-66-7

上下游产品

CAS号407-20-5 3-溴-5-氟吡啶

5-溴-3-氟吡啶置于正丁基锂,硼酸三异丙酯,盐酸,水,Sodium Hydroxide体系中,用 四氢呋喃,水 作为反应溶剂,化学反应 2.5H,以87.4%的收率获得产物5-氟-3-吡啶硼酸
参考文献: Processes And Intermediates For Producing Aminobenzimidazole Ureas[fr] Procédés Et Produits Intermédiaires Pour Produire Des Urées D'Aminobenzimidazole
标题: Processes And Intermediates For Producing Aminobenzimidazole Ureas[fr] Procédés Et Produits Intermédiaires Pour Produire Des Urées D'Aminobenzimidazole

专利信息

专利号:US-12150934-B2
优先权日:2016-11-30
标 题 :Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases
发明人：SIDDIQUI ARSHAD M; CIBLAT STEPHANE; CONSTANTINEAU-FORGET LEA; GRAND-MAITRE CHANTAL; GUO XIANGYU; SRIVASTAVA SANJAY; SHIPPS GERALD W; COOPER ALAN B; OZA VIBHA; KOSTURA MATTHEW W; LUTHER MICHAEL; LEVINE JEDD
权利人:BANTAM PHARMACEUTICAL LLC
摘要:Disclosed are methods of treating hyperproliferative disorders such as cancer, methods of arresting the cell cycle in cancer cells, methods of inhibiting glutathione synthesis in cancer cells, and associated compounds for use and uses in medicaments. In certain embodiments, the methods, uses and compounds are provided with reference to compounds of the structural formula (I), in which X1, X2, Z1, Z2, the ring system denoted by “aâ€?, R1, L1, L2, Q, L3, R3, L4, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein are especially active against cancers having a mutant KRAS gene.

专利号:WO-2024008625-A1
优先权日:2022-07-04
标 题:Procedure for the synthesis of tirbanibulin

专利号:EP-4302831-B1
优先权日:2022-07-04
标 题 :Process for synthesis of tirbanibulin
发明人：COLOMBO CARLO MARINO; BOTTA DANIELA; CRIPPA LORENZO
权利人:TRIFARMA S P A

专利号:EP-4302831-A1
优先权日:2022-07-04
标题 :Process for synthesis of tirbanibulin