CAS: 149507-26-6; (3-Fluoro-4-Methoxyphenyl)Boronic Acid

相似化合物

754226-34-1 208641-98-9 897958-93-9

上下游产品

CAS号2357-52-0 4-溴-2-氟苯甲醚 | CAS号5419-55-6 硼酸三异丙酯 | CAS号1098984-27-0 5-(3-fluoro-4-m... | CAS号106291-23-0 2-fluoro-1-meth... | CAS号331-62-4 3-氟-4-甲氧基苯腈 | CAS号716344-20-6 4-(2-Cyano-4-(t... | CAS号99452-78-5 3-chloro-6-(3-f...

4-溴-2-氟苯甲醚 反应生成3-氟-4-甲氧基苯硼酸
参考文献:Substituted Terphenyl Compounds For The Treatment Of Inflammation
标题:Substituted Terphenyl Compounds For The Treatment Of Inflammation
摘要:描述了一类三联苯化合物,用于治疗炎症和与炎症相关的疾病.特别感兴趣的化合物由formula Ii定义:其中r.Sup.2和r.Sup.3中的每一个都独立地选择自氢和卤素;或者其中r.Sup.2和r.Sup.3一起形成--och.Sub.2 O--;其中r.Sup.6到r.Sup.8中的每一个都独立地选择自氢,较低烷基,卤素,较低烷氧基,较低卤代烷基和较低二烷基氨基;或者其中r.Sup.6和r.Sup.7一起形成--och.Sub.2 O;其中r.Sup.12从较低烷基磺酰基和氨基磺酰基中选择;或其药用可接受盐.

专利信息

专利号:US-7557237-B2
优先权日:2003-09-09
标题:Process for the synthesis of 3-(3-fluoro-4-hydroxyphenyl)-7-hydroxynaphthonitrile
发明人：WU YANZHONG; REN JIANXIN; GHOSH MOUSUMI; LEVENT MAHMUT; SUTHERLAND KAREN W; RAVEENDRANATH PANOLIL
权利人:WYETH CORP
摘要:A process for making a compound of formula I n nand intermediate compounds thereof, wherein R 1 is CN, F or Cl; R 2 is H or Br; and R 3 and R 4 are each independently H or F. The compounds of formula I are useful in the treatment of chronic inflammatory diseases, such as rheumatoid arthritis.

专利号:US-2022259212-A1
优先权日:2019-07-11
标题:Inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan 2,3-dioxygenase
发明人：BOSS CHRISTOPH; CREN SYLVAINE; KIMMERLIN THIERRY; LOTZ-JENNE CARINA; POTHIER JULIEN; TIDTEN-LUKSCH NAOMI
权利人:IDORSIA PHARMACEUTICALS LTD
摘要:The present invention relates to compounds of Formula (I) inhibiting indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) enzymes. Further, their synthesis and their use as medicaments in the treatment of inter alia cancer is disclosed.

专利号:US-10253004-B2
优先权日:2017-01-26
标 题:Indanylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
发明人：ECKHARDT MATTHIAS; WAGNER HOLGER; PETERS STEFAN
权利人:BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of formula I, n nwherein the groups R, R 1 , R 2 , R 3 , m and n are defined herein, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

专利号:US-10125101-B2
优先权日:2016-11-28
标题:Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
发明人：ECKHARDT MATTHIAS; WAGNER HOLGER; PETERS STEFAN
权利人:BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of general formula I, n nwherein the groups R, R 1 , R 2 , R 3 , m and n are as defined herein, which compounds have valuable pharmacological properties, in particular their ability to bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular type 2 diabetes. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

专利号:US-2005054870-A1
优先权日:2003-09-09
标题:Process for the synthesis of 3-(3-fluoro-4-hydroxyphenyl)-7-hydroxynaphthonitrile

专利号:WO-2005026105-A2
优先权日:2003-09-09
标题 :Process for the synthesis of 3-(3-fluoro-4-hydroxyphenyl)-7-hydroxynaphthonitrile