专利号:US-11970435-B2 优先权日:2017-05-12 标题:Taste-modified creatine salts, compounds, compositions and uses thereof 发明人:LEBEDYEVA IRYNA; KLUG CHRISTOPHER 权利人:UNIV RES INST INC AUGUSTA 摘要:Provided are embodiments of creatine and creatine ethyl ester (CEE) salts where the anion is an artificial (non-saccharide) taste-modifier. These compounds represent stable white non-hygroscopic solids or semisolids that can readily dissolve in water and buffer solutions. Synthesis of novel creatine salts using environmentally safe solvents such as ethanol resulted in the formation of products in quantitative yields with sodium or potassium chloride as a byproduct. The creatine and creatine alkyl eater derivative salts are stable sweet-tasting compounds that are more palatable to a consumer than creatine or derivatives thereof.